Dystroglycan Produits
(Dystroglycan 1 (DAG1))
Catégories
Dystroglycan is a laminin binding component of the dystrophin-glycoprotein complex which provides a linkage between the subsarcolemmal cytoskeleton and the extracellular matrix. Dystroglycan 1 is a candidate gene for the site of the mutation in autosomal recessive muscular dystrophies. The dramatic reduction of dystroglycan 1 in Duchenne muscular dystrophy leads to a loss of linkage between the sarcolemma and extracellular matrix, rendering muscle fibers more susceptible to necrosis. Dystroglycan also functions as dual receptor for agrin and laminin-2 in the Schwann cell membrane. The muscle and nonmuscle isoforms of dystroglycan differ by carbohydrate moieties but not protein sequence. Alternative splicing results in multiple transcript variants all encoding the same protein.[provided by RefSeq, Apr 2010].
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Catégories Dystroglycan en vedette
Dystroglycan Anticorps
High quality antibodies with extensive validation data.
Dystroglycan Kits ELISA
Reliable ELISA kits for a wide range of species.
Dystroglycan Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
Dystroglycan recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse
Application
WB, IHC (p)
Validations
- (5)
N° du produit
ABIN658022
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ICC, IHC (p), IF
Validations
- (1)
- (4)
N° du produit
ABIN2856020
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (3)
N° du produit
ABIN7434920
Quantité
100 μL
Fiche technique
Fiche technique
Dystroglycan recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Various Species
Analytical Method
Quantitative Competition ELISA
Validations
- (4)
- (1)
N° du produit
ABIN6955481
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6955482
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6955483
Quantité
96 tests
Fiche technique
Fiche technique
Dystroglycan recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (2)
- (1)
N° du produit
ABIN1351078
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7122728
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7396379
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits Dystroglycan
: "Bouchardatine analogue alleviates non-alcoholic hepatic fatty liver disease/non-alcoholic steatohepatitis in high-fat fed mice by inhibiting ATP synthase activity." dans: British journal of pharmacology, Vol. 176, Issue 16, pp. 2877-2893, (2020) (PubMed).: "The Ying and Yang of Adenosine A1 and A2A Receptors on ERK1/2 Activation in a Rat Model of Global Cerebral Ischemia Reperfusion Injury." dans: Molecular neurobiology, Vol. 55, Issue 2, pp. 1284-1298, (2019) (PubMed).
: "Low wnt/β-catenin signaling determines leaky vessels in the subfornical organ and affects water homeostasis in mice." dans: eLife, Vol. 8, (2019) (PubMed).
: "Detection of variants in dystroglycanopathy-associated genes through the application of targeted whole-exome sequencing analysis to a large cohort of patients with unexplained limb-girdle muscle ..." dans: Skeletal muscle, Vol. 8, Issue 1, pp. 23, (2018) (PubMed).
: "PEDF protects cardiomyocytes by promoting FUNDC1‑mediated mitophagy via PEDF-R under hypoxic condition." dans: International journal of molecular medicine, Vol. 41, Issue 6, pp. 3394-3404, (2018) (PubMed).
: "Friedreich Ataxia: Developmental Failure of the Dorsal Root Entry Zone." dans: Journal of neuropathology and experimental neurology, Vol. 76, Issue 11, pp. 969-977, (2017) (PubMed).
: "Isolation and characterization of neural stem cells from dystrophic mdx mouse." dans: Experimental cell research, Vol. 343, Issue 2, pp. 190-207, (2016) (PubMed).
: "Pigment Epithelium-Derived Factor (PEDF) Improves Ischemic Cardiac Functional Reserve Through Decreasing Hypoxic Cardiomyocyte Contractility Through PEDF Receptor (PEDF-R)." dans: Journal of the American Heart Association, Vol. 5, Issue 7, (2016) (PubMed).
: "A High-Throughput Assay for the Detection of α-Dystroglycan N-Terminus in Human Uterine Fluid to Determine Uterine Receptivity." dans: Journal of biomolecular screening, Vol. 21, Issue 4, pp. 408-13, (2016) (PubMed).
: "Aryl Hydrocarbon Receptor Plays Protective Roles against High Fat Diet (HFD)-induced Hepatic Steatosis and the Subsequent Lipotoxicity via Direct Transcriptional Regulation of Socs3 Gene Expression." dans: The Journal of biological chemistry, Vol. 291, Issue 13, pp. 7004-16, (2016) (PubMed).
Synonymes et noms alternatifs relatifs à Dystroglycan
DystroGlycaN (dgn-1), dystroglycan 1 L homeolog (dag1.L), DystroGlycaN (dgn-2), DystroGlycaN (dgn-3), dystroglycan 1 (DAG1), dystroglycan 1 S homeolog (dag1.S), dystroglycan 1 (Dag1), dystroglycan 1 (dag1), Dystroglycan (Dg), dystroglycan (LOC408826), clusterin (Clu), lymphocyte antigen 6 complex (Ly6), 156DAG, 156dag, A3a, a3a, AGRNR, agrnr, Ala-1, APOJ, atu, CG18250, CLI, CT41273, D9Wsu13e, DAG, dag, dag1, DAG1, dg, DG, dgn, DmDG, Dmel\\CG18250, Dp71, Dp427, dys, GB14967, H9/25, LOC398500, Ly-6, Ly-27, Ly27, MDDGC7, MDDGC9, MGC53537, RAB7, RATTRPM2B, SGP-2, SGP2, SP-40, SP40, TRPM-2, Trpm2, TRPM2B, Trpmb, wu:fb83d06, wu:fi25f06, wu:fi37b08, zgc:109786Protein level used designations for Dystroglycan
- DystroGlycaN family member (dgn-1)
- dystroglycan
- DystroGlycaN family member (dgn-2)
- DystroGlycaN family member (dgn-3)
- dystrophin-associated glycoprotein 1
- dystroglycan 1
- dystroglycan 1 (dystrophin-associated glycoprotein 1)
- RAB7, member RAS oncogene family
- glycine cleavage system T-protein
- alpha-dystroglycan
- beta-dystroglycan
- dystrophin associated glycoprotein 1
- CG18250-PA
- CG18250-PB
- CG18250-PC
- CG18250-PD
- Dg-PA
- Dg-PB
- Dg-PC
- Dg-PD
- atsugari
- dystroglycan-like
- dimeric acid glycoprotein
- sulfated glycoprotein 2
- testosterone repressed prostate message 2
- testosterone-repressed prostate message
- testostrone-repressed prostate message 2
- dystrophin-associated glycoprote
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