E2F2 Produits
(E2F Transcription Factor 2 (E2F2))
Catégories
The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F3, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner, and it exhibits overall 46% amino acid identity to E2F1. [provided by RefSeq, Jul 2008].
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Catégories E2F2 en vedette
E2F2 Anticorps
High quality antibodies with extensive validation data.
E2F2 Kits ELISA
Reliable ELISA kits for a wide range of species.
E2F2 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
E2F2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (4)
N° du produit
ABIN7172517
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, PLA
Validations
- (3)
N° du produit
ABIN515125
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB
Validations
- (2)
N° du produit
ABIN654438
Quantité
400 μL
Fiche technique
Fiche technique
E2F2 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6955490
Quantité
96 tests
Fiche technique
Fiche technique
E2F2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1352231
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1352233
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7505314
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits E2F2
: "GCN5 Potentiates Glioma Proliferation and Invasion via STAT3 and AKT Signaling Pathways." dans: International journal of molecular sciences, Vol. 16, Issue 9, pp. 21897-910, (2016) (PubMed).: "RAE-1 ligands for the NKG2D receptor are regulated by E2F transcription factors, which control cell cycle entry." dans: The Journal of experimental medicine, Vol. 209, Issue 13, pp. 2409-22, (2012) (PubMed).
: "Alpha-synuclein degradation by serine protease neurosin: implication for pathogenesis of synucleinopathies." dans: Human molecular genetics, Vol. 12, Issue 20, pp. 2625-35, (2003) (PubMed).
: "E2F-6, a member of the E2F family that can behave as a transcriptional repressor." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 6, pp. 2850-5, (1998) (PubMed).
: "Nuclear localization of DP and E2F transcription factors by heterodimeric partners and retinoblastoma protein family members." dans: Journal of cell science, Vol. 109 ( Pt 7), Issue 25, pp. 1717-26, (1997) (PubMed).
: "E2F transcription factor action, regulation and possible role in human cancer." dans: Cell proliferation, Vol. 30, Issue 3-4, pp. 97-105, (1997) (PubMed).
: "Deregulated expression of E2F family members induces S-phase entry and overcomes p16INK4A-mediated growth suppression." dans: Molecular and cellular biology, Vol. 16, Issue 3, pp. 1047-57, (1996) (PubMed).
: "E2F: a link between the Rb tumor suppressor protein and viral oncoproteins." dans: Science (New York, N.Y.), Vol. 258, Issue 5081, pp. 424-9, (1992) (PubMed).
Synonymes et noms alternatifs relatifs à E2F2
E2F transcription factor 2 (E2F2), E2F transcription factor 2 (E2f2), si:ch211-160f23.5 (si:ch211-160f23.5), 9230110J10, CG1071, dE2F-2, dE2F2, dE2f2, de2f2, Dmel\\CG1071, E2F, E2F-2, E2F2, e2f2, E130207A07, fb40b03, wu:fb40b03Protein level used designations for E2F2
- transcription factor E2F2
- CG1071-PA
- E2f2-PA
- E2F-2
- LOW QUALITY PROTEIN: transcription factor E2F2
- E2F transcription factor 2
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