E2F5 Produits
(E2F5)
Catégories
The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionarily conserved domains that are present in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein is differentially phosphorylated and is expressed in a wide variety of human tissues. It has higher identity to E2F4 than to other family members. Both this protein and E2F4 interact with tumor suppressor proteins p130 and p107, but not with pRB. Alternative splicing results in multiple variants encoding different isoforms. [provided by RefSeq, Jul 2008].
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Catégories E2F5 en vedette
E2F5 Anticorps
High quality antibodies with extensive validation data.
E2F5 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
E2F5 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, FACS, IHC (p)
Validations
- (1)
- (3)
N° du produit
ABIN652951
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human, Rat
Application
WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
- (1)
- (2)
N° du produit
ABIN733673
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC
Validations
- (2)
N° du produit
ABIN7006970
Quantité
20 μL
Fiche technique
Fiche technique
E2F5 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative DNA-Binding ELISA
Validations
N° du produit
ABIN5648569
Quantité
96 tests
Fiche technique
Fiche technique
E2F5 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3079243
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3122979
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN2719897
Quantité
50 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits E2F5
: "The Effects of miR-20a on p21: Two Mechanisms Blocking Growth Arrest in TGF-β-Responsive Colon Carcinoma." dans: Journal of cellular physiology, Vol. 230, Issue 12, pp. 3105-14, (2015) (PubMed).: "NFkB is activated by multiple mechanisms in hairy cell leukemia." dans: Genes, chromosomes & cancer, Vol. 54, Issue 7, pp. 418-32, (2015) (PubMed).
: "Sj7170, a unique dual-function peptide with a specific ?-chymotrypsin inhibitory activity and a potent tumor-activating effect from scorpion venom." dans: The Journal of biological chemistry, Vol. 289, Issue 17, pp. 11667-80, (2014) (PubMed).
: "Analysis of genetic aberrations on chromosomal region 8q21-24 identifies E2F5 as an oncogene with copy number gain in prostate cancer." dans: Medical oncology (Northwood, London, England), Vol. 30, Issue 1, pp. 465, (2013) (PubMed).
Synonymes et noms alternatifs relatifs à E2F5
E2F transcription factor 5 (E2f5), E2F transcription factor 5 (e2f5), E2F transcription factor 5 (E2F5), AU024671, cb735, E2F-5, E2f-5, E2F4, zgc:111879Protein level used designations for E2F5
- transcription factor E2F5
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