Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

E2F5 Produits

(E2F5)

Catégories

The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionarily conserved domains that are present in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein is differentially phosphorylated and is expressed in a wide variety of human tissues. It has higher identity to E2F4 than to other family members. Both this protein and E2F4 interact with tumor suppressor proteins p130 and p107, but not with pRB. Alternative splicing results in multiple variants encoding different isoforms. [provided by RefSeq, Jul 2008].

antibodies-online.com est synonyme de produits de recherche de haute qualité. Cherchez, trouvez et commandez des outils avec des données de validation étendues, des images, des références. Notre service clientèle scientifique est toujours à votre disposition si vous avez des questions sur la sélection ou l'application de nos produits.

Catégories E2F5 en vedette

E2F5 Anticorps

High quality antibodies with extensive validation data.

E2F5 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

E2F5 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, FACS, IHC (p)
Validations
  • (1)
  • (3)
N° du produit ABIN652951
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human, Rat
Application WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (1)
  • (2)
N° du produit ABIN733673
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (2)
N° du produit ABIN7006970
Quantité 20 μL
Fiche technique Fiche technique

E2F5 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Analytical Method Qualitative DNA-Binding ELISA
Validations
N° du produit ABIN5648569
Quantité 96 tests
Fiche technique Fiche technique

E2F5 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3079243
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3122979
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN2719897
Quantité 50 μg
Fiche technique Fiche technique

Dernières publications sur nos produits E2F5

Sokolova, Fiorino, Zoni, Crippa, Reid, Gariboldi, Pierotti: "The Effects of miR-20a on p21: Two Mechanisms Blocking Growth Arrest in TGF-β-Responsive Colon Carcinoma." dans: Journal of cellular physiology, Vol. 230, Issue 12, pp. 3105-14, (2015) (PubMed).

Nagel, Ehrentraut, Meyer, Kaufmann, Drexler, MacLeod: "NFkB is activated by multiple mechanisms in hairy cell leukemia." dans: Genes, chromosomes & cancer, Vol. 54, Issue 7, pp. 418-32, (2015) (PubMed).

Song, Gong, Yan, Hong, Wang, Wu, Li, Li, Cao: "Sj7170, a unique dual-function peptide with a specific ?-chymotrypsin inhibitory activity and a potent tumor-activating effect from scorpion venom." dans: The Journal of biological chemistry, Vol. 289, Issue 17, pp. 11667-80, (2014) (PubMed).

Zhao, Wu, Ling, Lin, Fu, Deng, He, Zhong: "Analysis of genetic aberrations on chromosomal region 8q21-24 identifies E2F5 as an oncogene with copy number gain in prostate cancer." dans: Medical oncology (Northwood, London, England), Vol. 30, Issue 1, pp. 465, (2013) (PubMed).

Synonymes et noms alternatifs relatifs à E2F5

E2F transcription factor 5 (E2f5), E2F transcription factor 5 (e2f5), E2F transcription factor 5 (E2F5), AU024671, cb735, E2F-5, E2f-5, E2F4, zgc:111879

Protein level used designations for E2F5

  • transcription factor E2F5
Vous êtes ici:
Support technique