E2F6 Produits
(E2F Transcription Factor 6 (E2F6))
Catégories
This gene encodes a member of the E2F transcription factor protein family. E2F family members play a crucial role in control of the cell cycle and of the action of tumor suppressor proteins. They are also a target of the transforming proteins of small DNA tumor viruses. Many E2F proteins contain several evolutionarily conserved domains: a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. The encoded protein of this gene is atypical because it lacks the transactivation and tumor suppressor protein association domains. It contains a modular suppression domain and is an inhibitor of E2F-dependent transcription. The protein is part of a multimeric protein complex that contains a histone methyltransferase and the transcription factors Mga and Max. Multiple transcript variants have been reported for this gene, but it has not been clearly demonstrated that they encode valid isoforms. [provided by RefSeq, Jul 2008].
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Catégories E2F6 en vedette
E2F6 Anticorps
High quality antibodies with extensive validation data.
E2F6 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
E2F6 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA, IF, ICC
Validations
- (1)
- (4)
N° du produit
ABIN6261413
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF, IP, ChIP
Validations
- (4)
N° du produit
ABIN1679632
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, IHC, ELISA
Validations
- (3)
N° du produit
ABIN7234987
Quantité
200 μL
Fiche technique
Fiche technique
E2F6 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1352242
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
N° du produit
ABIN7547202
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
HEK-293 Cells
Validations
N° du produit
ABIN7562444
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits E2F6
: "Sesquiterpene binding Gly-Leu-Ser/Lys-"co-adaptation pocket" to inhibit lung cancer cell epithelial-mesenchymal transition." dans: Oncotarget, Vol. 8, Issue 41, pp. 70192-70203, (2018) (PubMed).: "Human papillomavirus type 16 E7 oncoprotein associates with E2F6." dans: Journal of virology, Vol. 82, Issue 17, pp. 8695-705, (2008) (PubMed).
: "A comprehensive ChIP-chip analysis of E2F1, E2F4, and E2F6 in normal and tumor cells reveals interchangeable roles of E2F family members." dans: Genome research, Vol. 17, Issue 11, pp. 1550-61, (2007) (PubMed).
: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." dans: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).
Synonymes et noms alternatifs relatifs à E2F6
E2F transcription factor 6 (E2F6), E2F transcription factor 6 (E2f6), AI462434, E2F-6, E2F6b, EMAProtein level used designations for E2F6
- E2F transcription factor 6
- transcription factor E2F6
- E2F-6
- E2F-binding site-modulating activity protein
- transcriptional repressor E2F6
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