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E2F6 Produits

(E2F Transcription Factor 6 (E2F6))

Catégories

This gene encodes a member of the E2F transcription factor protein family. E2F family members play a crucial role in control of the cell cycle and of the action of tumor suppressor proteins. They are also a target of the transforming proteins of small DNA tumor viruses. Many E2F proteins contain several evolutionarily conserved domains: a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. The encoded protein of this gene is atypical because it lacks the transactivation and tumor suppressor protein association domains. It contains a modular suppression domain and is an inhibitor of E2F-dependent transcription. The protein is part of a multimeric protein complex that contains a histone methyltransferase and the transcription factors Mga and Max. Multiple transcript variants have been reported for this gene, but it has not been clearly demonstrated that they encode valid isoforms. [provided by RefSeq, Jul 2008].

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Catégories E2F6 en vedette

E2F6 Anticorps

High quality antibodies with extensive validation data.

E2F6 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

E2F6 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, IF, ICC
Validations
  • (1)
  • (4)
N° du produit ABIN6261413
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IF, IP, ChIP
Validations
  • (4)
N° du produit ABIN1679632
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, IHC, ELISA
Validations
  • (3)
N° du produit ABIN7234987
Quantité 200 μL
Fiche technique Fiche technique

E2F6 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1352242
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3079106
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3131804
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits E2F6

Ai, Zhang, Gao, Qin, Zhong, Gu, Li, Qiao, Tian, Cui, Yang, Bi, Xiao, Chen, Liu, Zhou, Sun, Yang: "Sesquiterpene binding Gly-Leu-Ser/Lys-"co-adaptation pocket" to inhibit lung cancer cell epithelial-mesenchymal transition." dans: Oncotarget, Vol. 8, Issue 41, pp. 70192-70203, (2018) (PubMed).

McLaughlin-Drubin, Huh, Münger: "Human papillomavirus type 16 E7 oncoprotein associates with E2F6." dans: Journal of virology, Vol. 82, Issue 17, pp. 8695-705, (2008) (PubMed).

Xu, Bieda, Jin, Rabinovich, Oberley, Green, Farnham: "A comprehensive ChIP-chip analysis of E2F1, E2F4, and E2F6 in normal and tumor cells reveals interchangeable roles of E2F family members." dans: Genome research, Vol. 17, Issue 11, pp. 1550-61, (2007) (PubMed).

Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." dans: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

Synonymes et noms alternatifs relatifs à E2F6

E2F transcription factor 6 (E2F6), E2F transcription factor 6 (E2f6), AI462434, E2F-6, E2F6b, EMA

Protein level used designations for E2F6

  • E2F transcription factor 6
  • transcription factor E2F6
  • E2F-6
  • E2F-binding site-modulating activity protein
  • transcriptional repressor E2F6
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