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EIF3A Produits

(Eukaryotic Translation Initiation Factor 3 Subunit A (EIF3A))
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.

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Catégories EIF3A en vedette

EIF3A Anticorps

High quality antibodies with extensive validation data.

EIF3A Kits ELISA

Reliable ELISA kits for a wide range of species.

EIF3A Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

EIF3A recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse
Application WB, IHC, IF
Validations
  • (3)
N° du produit ABIN7254935
Quantité 200 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IF
Validations
  • (1)
  • (2)
N° du produit ABIN1679692
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IF
Validations
  • (2)
N° du produit ABIN7152145
Quantité 100 μg
Fiche technique Fiche technique

EIF3A recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6966611
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method
Validations
N° du produit ABIN1132475
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method
Validations
N° du produit ABIN1132476
Quantité 96 tests
Fiche technique Fiche technique

EIF3A recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1352552
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits EIF3A

Jeong, Park, Nguyen, Hwang, Lee, Giong, Lee, Yoon, Lee, Kim, Kim, Kim, Yang, Kim, Lee, Yu, Sonenberg, Kim, Kim: "A threonyl-tRNA synthetase-mediated translation initiation machinery." dans: Nature communications, Vol. 10, Issue 1, pp. 1357, (2019) (PubMed).

Yang, Hu, Fan, Zhang, Zhong, Guo, Qin, Chen: "Picornavirus 2A protease regulates stress granule formation to facilitate viral translation." dans: PLoS pathogens, Vol. 14, Issue 2, pp. e1006901, (2018) (PubMed).

Toompuu, Kärblane, Pata, Truve, Sarmiento: "ABCE1 is essential for S phase progression in human cells." dans: Cell cycle (Georgetown, Tex.), Vol. 15, Issue 9, pp. 1234-47, (2016) (PubMed).

Lee, Kranzusch, Cate: "eIF3 targets cell-proliferation messenger RNAs for translational activation or repression." dans: Nature, Vol. 522, Issue 7554, pp. 111-4, (2015) (PubMed).

Chazal, Daguenet, Wendling, Ulryck, Tomasetto, Sargueil, Le Hir: "EJC core component MLN51 interacts with eIF3 and activates translation." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 15, pp. 5903-8, (2013) (PubMed).

Kroczynska, Kaur, Katsoulidis, Majchrzak-Kita, Sassano, Kozma, Fish, Platanias: "Interferon-dependent engagement of eukaryotic initiation factor 4B via S6 kinase (S6K)- and ribosomal protein S6K-mediated signals." dans: Molecular and cellular biology, Vol. 29, Issue 10, pp. 2865-75, (2009) (PubMed).

Synonymes et noms alternatifs relatifs à EIF3A

eukaryotic translation initiation factor 3 subunit A (EIF3A), eukaryotic translation initiation factor 3, subunit A (Eif3a), eukaryotic translation initiation factor 3 subunit A S homeolog (eif3a.S), translation initiation factor eIF3a (tif32), eukaryotic translation initiation factor 3 subunit A (Eif3a), A830012B05Rik, Csma, EIF3, Eif3, eIF3 p110, eIF3-p170, eIF3-theta, eIF3a, EIF3S10, Eif3s10, eif3s10, EIF6, mKIAA0139, P167, p180, p185, TIF32, ZH12

Protein level used designations for EIF3A

  • EIF3, p180 subunit
  • centrosomin homolog
  • cytoplasmic protein p167
  • eIF-3-theta
  • eIF3 p167
  • eIF3 p180
  • eIF3 p185
  • eukaryotic translation initiation factor 3 subunit 10
  • eukaryotic translation initiation factor 3 subunit A
  • eukaryotic translation initiation factor 3, subunit 10 (theta, 150/170kD)
  • eukaryotic translation initiation factor 3, subunit 10 (theta, 170kD)
  • eukaryotic translation initiation factor 3, subunit 10 theta, 150/170kDa
  • eukaryotic translation initiation factor 3, subunit 10, 170kD
  • eukaryotic translation initiation factor 6
  • EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 10 (EIF-3 THETA) (EIF3 P167) (EIF3 P180) (EIF3 P185) (P162 PROTEIN) (CENTROSOMIN)
  • centrosomin
  • eukaryotic translation initiation factor 3, subunit 10 (theta)
  • p162
  • Eukaryotic translation initiation factor 3 subunit 10
  • Eukaryotic translation initiation factor 3 110 kDa subunit
  • Translation initiation factor eIF3, p110 subunit
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