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eIF4EBP1 Produits

(Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))
This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq, Jul 2008].

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Catégories eIF4EBP1 en vedette

eIF4EBP1 Anticorps

High quality antibodies with extensive validation data.

eIF4EBP1 Kits ELISA

Reliable ELISA kits for a wide range of species.

eIF4EBP1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

eIF4EBP1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse
Application WB, ELISA, IHC (p), IF (cc), IF (p), FACS, IHC (fro)
Validations
  • (5)
N° du produit ABIN682978
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application IHC, ELISA, FACS, ICC
Validations
  • (5)
N° du produit ABIN5611114
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IF
Validations
  • (3)
  • (4)
N° du produit ABIN3021844
Quantité 100 μL
Fiche technique Fiche technique

eIF4EBP1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN1380515
Quantité 2 x 96 tests
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN1380514
Quantité 2 x 96 tests
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN1380149
Quantité 2 x 96 tests
Fiche technique Fiche technique

eIF4EBP1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7122851
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1352602
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN2129067
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits eIF4EBP1

Teng, Zhao, Gao, He, Li, Chen, Feng, Yi: "20(s)-Protopanaxadiol (PPD) increases the radiotherapy sensitivity of laryngeal carcinoma." dans: Food & function, Vol. 8, Issue 12, pp. 4469-4477, (2018) (PubMed).

Li, Chan, Yu, Bei, Chen, Zhou, Cheng, Chen, Ziegler, Rowe, Das, Xiao: "miR-29b contributes to multiple types of muscle atrophy." dans: Nature communications, Vol. 8, pp. 15201, (2018) (PubMed).

Li, Liu, Chang, Zou, Xing: "Downregulation of MCL-1 and upregulation of PUMA using mTOR inhibitors enhance antitumor efficacy of BH3 mimetics in triple-negative breast cancer." dans: Cell death & disease, Vol. 9, Issue 2, pp. 137, (2018) (PubMed).

Zhou, Liu, Xue, Zheng, Liu, Ma, Li, Liu et al.: "Combination of Endothelial-Monocyte-Activating Polypeptide-II with Temozolomide Suppress Malignant Biological Behaviors of Human Glioblastoma Stem Cells via miR-590-3p/MACC1 Inhibiting PI3K/AKT/mTOR ..." dans: Frontiers in molecular neuroscience, Vol. 10, pp. 68, (2017) (PubMed).

Guo, Hu, Chen, Li, Ye, Cheng, Zhang, He: "iTRAQ-based comparative proteomic analysis of Vero cells infected with virulent and CV777 vaccine strain-like strains of porcine epidemic diarrhea virus." dans: Journal of proteomics, Vol. 130, pp. 65-75, (2016) (PubMed).

Romasko, Amarnath, Midic, Latham: "Association of maternal mRNA and phosphorylated EIF4EBP1 variants with the spindle in mouse oocytes: localized translational control supporting female meiosis in mammals." dans: Genetics, Vol. 195, Issue 2, pp. 349-58, (2014) (PubMed).

Fei, Zhang, Dong, Cheng, Zhang, Huang, Zhou, Xie, Chen, Wu: "Targeting mTOR to overcome epidermal growth factor receptor tyrosine kinase inhibitor resistance in non-small cell lung cancer cells." dans: PLoS ONE, Vol. 8, Issue 7, pp. e69104, (2013) (PubMed).

Chauhan, Singh, Rai, Rai, Rai: "Distinct autoantibody profiles in systemic lupus erythematosus patients are selectively associated with TLR7 and TLR9 upregulation." dans: Journal of clinical immunology, Vol. 33, Issue 5, pp. 954-64, (2013) (PubMed).

Saha, Jiang, Yang, Zhu, Wang, Schimmer, Qiu, Chang: "Targeting p53 via JNK pathway: a novel role of RITA for apoptotic signaling in multiple myeloma." dans: PLoS ONE, Vol. 7, Issue 1, pp. e30215, (2012) (PubMed).

Lang, Kazi, Hong-Brown, Lang: "Delayed recovery of skeletal muscle mass following hindlimb immobilization in mTOR heterozygous mice." dans: PLoS ONE, Vol. 7, Issue 6, pp. e38910, (2012) (PubMed).

Synonymes et noms alternatifs relatifs à eIF4EBP1

eukaryotic translation initiation factor 4E binding protein 1 (EIF4EBP1), eukaryotic translation initiation factor 4E binding protein 1 (Eif4ebp1), CG8846 gene product from transcript CG8846-RA (Thor), eukaryotic translation initiation factor 4E binding protein 1 (eif4ebp1), 4E-BP, 4e-bp, 4E-BP1, 4e-bp1, 4EBP, 4eBP, 4ebp, 4EBP1, 43-BP, 153432_at, AA959816, anon-WO0172774.158, BcDNA.HL08053, BcDNA:HL08053, BP-1, CG8846, CT8705, d4E-BP, d4e-bp, d4E-BP1, d4EBP, d4eBP, Dm 4E-BP, Dmel\\CG8846, dthor, eIF4E-BP, EIF4EBP1, fc04h09, l(2)06270, l(2)k07736, l(2)k13517, PHAS-I, Phas1, pp20, thor, Thor/EIF4EBP, wu:fc04h09, zgc:64137

Protein level used designations for eIF4EBP1

  • eIF4E-binding protein 1
  • eukaryotic translation initiation factor 4E-binding protein 1
  • phosphorylated heat- and acid-stable protein regulated by insulin 1
  • 4E-BP1
  • CG8846-PA
  • Eif4e-binding protein
  • Thor-PA
  • eIF-4E-binding protein
  • eif4e-binding protein 4EBP
  • eukaryotic initiation factor 4E binding protein
  • eukaryotic initiation factor 4E-binding protein
  • eukaryotic translation initiation factor 4E binding protein
  • eukaryotic translation initiation factor 4E-binding protein
  • insulin-stimulated eIF-4E binding protein
  • lethal (2) 06270
  • thor
  • eukaryotic translation initiation factor 4E binding protein 1
  • translation initiation factor 4E binding protein 1
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