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ENPP2 Produits

(Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2))
The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2008].

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Catégories ENPP2 en vedette

ENPP2 Anticorps

High quality antibodies with extensive validation data.

ENPP2 Kits ELISA

Reliable ELISA kits for a wide range of species.

ENPP2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

ENPP2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, FACS, ICC, IF
Validations
  • (1)
  • (6)
N° du produit ABIN2856278
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, FACS
Validations
  • (5)
N° du produit ABIN650746
Quantité 200 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (4)
N° du produit ABIN7427858
Quantité 100 μL
Fiche technique Fiche technique

ENPP2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6955502
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6955503
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6955504
Quantité 96 tests
Fiche technique Fiche technique

ENPP2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
N° du produit ABIN7274534
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
N° du produit ABIN7274543
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7122741
Quantité 50 μg
Fiche technique Fiche technique

Dernières publications sur nos produits ENPP2

Tsukahara, Haniu, Uemura, Matsuda: "Porcine liver decomposition product-derived lysophospholipids promote microglial activation in vitro." dans: Scientific reports, Vol. 10, Issue 1, pp. 3748, (2020) (PubMed).

Miao, Zhao, Han, Ma, Deng, Yang, Lü, Shao, Kong, Wang, Xu, Wang, Feng: "NSun2 regulates aneurysm formation by promoting autotaxin expression and T cell recruitment." dans: Cellular and molecular life sciences : CMLS, (2020) (PubMed).

Lee, Fiene, Li, Hanck, Brylev, Fedorov, Lecka, Haider, Pietzsch, Zimmermann, Sévigny, Kortz, Stephan, Müller: "Polyoxometalates--potent and selective ecto-nucleotidase inhibitors." dans: Biochemical pharmacology, Vol. 93, Issue 2, pp. 171-81, (2015) (PubMed).

Koike, Keino-Masu, Ohto, Masu: "The N-terminal hydrophobic sequence of autotaxin (ENPP2) functions as a signal peptide." dans: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 11, Issue 2, pp. 133-42, (2006) (PubMed).

Stefan, Jansen, Bollen: "NPP-type ectophosphodiesterases: unity in diversity." dans: Trends in biochemical sciences, Vol. 30, Issue 10, pp. 542-50, (2005) (PubMed).

Sato, Malchinkhuu, Muraki, Ishikawa, Hayashi, Tosaka, Mochiduki, Inoue, Tomura, Mogi, Nochi, Tamoto, Okajima: "Identification of autotaxin as a neurite retraction-inducing factor of PC12 cells in cerebrospinal fluid and its possible sources." dans: Journal of neurochemistry, Vol. 92, Issue 4, pp. 904-14, (2005) (PubMed).

Tanaka, Kishi, Takanezawa, Kakehi, Aoki, Arai: "Prostatic acid phosphatase degrades lysophosphatidic acid in seminal plasma." dans: FEBS letters, Vol. 571, Issue 1-3, pp. 197-204, (2004) (PubMed).

Strausberg, Feingold, Grouse, Derge, Klausner, Collins, Wagner, Shenmen, Schuler, Altschul, Zeeberg, Buetow, Schaefer, Bhat, Hopkins, Jordan, Moore, Max, Wang, Hsieh, Diatchenko, Marusina, Farmer et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, (2002) (PubMed).

Synonymes et noms alternatifs relatifs à ENPP2

ectonucleotide pyrophosphatase/phosphodiesterase 2 (ENPP2), ectonucleotide pyrophosphatase/phosphodiesterase 2 (Enpp2), ectonucleotide pyrophosphatase/phosphodiesterase 2 (enpp2), ectonucleotide pyrophosphatase/phosphodiesterase 2 L homeolog (enpp2.L), ectonucleotide pyrophosphatase/phosphodiesterase 2 S homeolog (enpp2.S), ATX, atx, ATX-X, AUTOTAXIN, autotaxin, enpp2, enpp2a, enpp2b, LysoPLD, MGC132047, NPP2, Npps2, PD-IALPHA, PD-Ialpha, PDNP2, Pdnp2, zgc:63550

Protein level used designations for ENPP2

  • E-NPP 2
  • autotaxin-t
  • ectonucleotide pyrophosphatase/phosphodiesterase family member 2
  • extracellular lysophospholipase D
  • phosphodiesterase I/nucleotide pyrophosphatase 2
  • plasma lysophospholipase D
  • autotaxin
  • lysoPLD
  • phosphodiesterase I/nucleotide pyrophosphatase 2 (autotaxin)
  • ectonucleotide pyrophosphatase/phosphodiesterase 2 (autotaxin)
  • ectonucleotide pyrophosphatase/phosphodiesterase 2
  • ectonucleotide pyrophosphatase/phosphodiesterase family member 2 isoform 2 preproprotein
  • ectonucleotide pyrophosphatase/phosphodiesterase 2 S homeolog
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