EP400 Produits
(E1A Binding Protein P400 (EP400))
Catégories
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. May be required for transcriptional activation of E2F1 and MYC target genes during cellular proliferation. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400 (By similarity). Regulates transcriptional activity of ZNF42.
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Catégories EP400 en vedette
EP400 Anticorps
High quality antibodies with extensive validation data.
EP400 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
- (2)
N° du produit
ABIN528254
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF
Validations
- (2)
N° du produit
ABIN528253
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB
Validations
- (1)
N° du produit
ABIN6140195
Quantité
100 μL
Fiche technique
Fiche technique
EP400 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1352867
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits EP400
: "ANP32E is a histone chaperone that removes H2A.Z from chromatin." dans: Nature, Vol. 505, Issue 7485, pp. 648-53, (2014) (PubMed).: "Basal activity of a PARP1-NuA4 complex varies dramatically across cancer cell lines." dans: Cell reports, Vol. 8, Issue 6, pp. 1808-18, (2014) (PubMed).
: "PRC1 and PRC2 are not required for targeting of H2A.Z to developmental genes in embryonic stem cells." dans: PLoS ONE, Vol. 7, Issue 4, pp. e34848, (2012) (PubMed).
: "Hepatitis C virus NS3 protein can activate the Notch-signaling pathway through binding to a transcription factor, SRCAP." dans: PLoS ONE, Vol. 6, Issue 6, pp. e20718, (2011) (PubMed).
: "Genome-wide siRNA screen identifies SMCX, EP400, and Brd4 as E2-dependent regulators of human papillomavirus oncogene expression." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 8, pp. 3752-7, (2010) (PubMed).
: "NCoR1 mediates papillomavirus E8;E2C transcriptional repression." dans: Journal of virology, Vol. 84, Issue 9, pp. 4451-60, (2010) (PubMed).
: "The p400 ATPase regulates nucleosome stability and chromatin ubiquitination during DNA repair." dans: The Journal of cell biology, Vol. 191, Issue 1, pp. 31-43, (2010) (PubMed).
: "VHL loss actuates a HIF-independent senescence programme mediated by Rb and p400." dans: Nature cell biology, Vol. 10, Issue 3, pp. 361-9, (2008) (PubMed).
Synonymes et noms alternatifs relatifs à EP400
E1A binding protein p400 (EP400), E1A binding protein p400 (Ep400), EP400 N-terminal-like protein (LOC738562), helicase domino (LOC5570719), E1a binding protein P400 (CpipJ_CPIJ007689), E1a binding protein P400 (CpipJ_CPIJ007688), E1a binding protein P400 (CpipJ_CPIJ007686), E1a binding protein P400 (CpipJ_CPIJ008061), 1700020J09Rik, AU023439, CAGH32, mDomino, mKIAA1498, P400, p400, TNRC12Protein level used designations for EP400
- CAG repeat protein 32
- E1A-binding protein p400
- domino homolog
- hDomino
- p400 SWI2/SNF2-related protein
- p400 kDa SWI2/SNF2-related protein
- trinucleotide repeat containing 12
- trinucleotide repeat-containing gene 12 protein
- E1A binding protein p400
- E1a binding protein P400
- e1A-binding protein p400-like
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