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EPS15 Produits

(Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15))
This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2009].

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Catégories EPS15 en vedette

EPS15 Anticorps

High quality antibodies with extensive validation data.

EPS15 Kits ELISA

Reliable ELISA kits for a wide range of species.

EPS15 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

EPS15 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB
Validations
  • (4)
N° du produit ABIN6140236
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application ELISA, IHC
Validations
  • (2)
N° du produit ABIN7244873
Quantité 200 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (2)
N° du produit ABIN6256811
Quantité 100 μL
Fiche technique Fiche technique

EPS15 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method
Validations
N° du produit ABIN1132100
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method
Validations
N° du produit ABIN1132101
Quantité 96 tests
Fiche technique Fiche technique

EPS15 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
N° du produit ABIN2714444
Quantité 20 μg
Fiche technique Fiche technique

Dernières publications sur nos produits EPS15

Engqvist-Goldstein, Warren, Kessels, Keen, Heuser, Drubin: "The actin-binding protein Hip1R associates with clathrin during early stages of endocytosis and promotes clathrin assembly in vitro." dans: The Journal of cell biology, Vol. 154, Issue 6, pp. 1209-23, (2001) (PubMed).

Kariya, Koyama, Nakashima, Oshiro, Morinaka, Kikuchi: "Regulation of complex formation of POB1/epsin/adaptor protein complex 2 by mitotic phosphorylation." dans: The Journal of biological chemistry, Vol. 275, Issue 24, pp. 18399-406, (2000) (PubMed).

Enmon, de Beer, Overduin: "Solution structure of Eps15's third EH domain reveals coincident Phe-Trp and Asn-Pro-Phe binding sites." dans: Biochemistry, Vol. 39, Issue 15, pp. 4309-19, (2000) (PubMed).

de Beer, Hoofnagle, Enmon, Bowers, Yamabhai, Kay, Overduin: "Molecular mechanism of NPF recognition by EH domains." dans: Nature structural biology, Vol. 7, Issue 11, pp. 1018-22, (2000) (PubMed).

Traub, Downs, Westrich, Fremont: "Crystal structure of the alpha appendage of AP-2 reveals a recruitment platform for clathrin-coat assembly." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 16, pp. 8907-12, (1999) (PubMed).

Iannolo, Salcini, Gaidarov, Goodman, Baulida, Carpenter, Pelicci, Di Fiore, Keen: "Mapping of the molecular determinants involved in the interaction between eps15 and AP-2." dans: Cancer research, Vol. 57, Issue 2, pp. 240-5, (1997) (PubMed).

Alvarez, Shon, Miloso, Beguinot: "Structural requirements of the epidermal growth factor receptor for tyrosine phosphorylation of eps8 and eps15, substrates lacking Src SH2 homology domains." dans: The Journal of biological chemistry, Vol. 270, Issue 27, pp. 16271-6, (1995) (PubMed).

Synonymes et noms alternatifs relatifs à EPS15

epidermal growth factor receptor pathway substrate 15 (EPS15), Epidermal growth factor receptor pathway substrate clone 15 (Eps-15), epidermal growth factor receptor pathway substrate 15 (eps15), epidermal growth factor receptor pathway substrate 15 (Eps15), hypothetical protein (PGTG_06574), 2410112D09Rik, AF-1P, AF1P, anon-WO0118547.85, CG16932, Dmel\\CG16932, EH1, EPS-15, eps-15, Eps15, eps15, i31, MLLT5, RGD1307641

Protein level used designations for EPS15

  • ALL1 fused gene from chromosome 1
  • epidermal growth factor receptor substrate 15
  • protein AF-1p
  • CG16932-PA
  • CG16932-PB
  • CG16932-PC
  • CG16932-PD
  • Eps-15-PA
  • Eps-15-PB
  • Eps-15-PC
  • Eps-15-PD
  • Eps15 homologue 1
  • epidermal growth factor receptor pathway substrate clone 15
  • epidermal growth factor receptor pathway substrate 15
  • epidermal growth factor receptor substrate 15-like
  • epidermal growth factor pathway substrate 15
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