ERCC2 Produits
(Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 2 (ERCC2))
Catégories
The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008].
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Catégories ERCC2 en vedette
ERCC2 Anticorps
High quality antibodies with extensive validation data.
ERCC2 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
ERCC2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse
Application
WB, IF, ICC, IHC (p)
Validations
- (4)
N° du produit
ABIN2856090
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
N° du produit
ABIN7171956
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (3)
N° du produit
ABIN515384
Quantité
100 μg
Fiche technique
Fiche technique
ERCC2 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6960582
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN5608594
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN5660069
Quantité
96 tests
Fiche technique
Fiche technique
ERCC2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
N° du produit
ABIN1353031
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1353033
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7418473
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits ERCC2
: "XPD localizes in mitochondria and protects the mitochondrial genome from oxidative DNA damage." dans: Nucleic acids research, Vol. 43, Issue 11, pp. 5476-88, (2015) (PubMed).: "Cadmium inhibits non-homologous end-joining and over-activates the MRE11-dependent repair pathway." dans: Mutation research, Vol. 654, Issue 1, pp. 13-21, (2008) (PubMed).
: "Mutations in the XPD helicase gene result in XP and TTD phenotypes, preventing interaction between XPD and the p44 subunit of TFIIH." dans: Nature genetics, Vol. 20, Issue 2, pp. 184-8, (1998) (PubMed).
Synonymes et noms alternatifs relatifs à ERCC2
ERCC excision repair 2, TFIIH core complex helicase subunit (ERCC2), excision repair cross-complementing rodent repair deficiency, complementation group 2 (Ercc2), ERCC excision repair 2, TFIIH core complex helicase subunit (Ercc2), excision repair cross-complementation group 2 (ercc2), Xeroderma pigmentosum D (Xpd), AA407812, AU020867, AW240756, CG9433, COFS2, CXPD, DhR3, DhXPD, Dmel\\CG9433, DmXPD, EM9, Ercc-2, ERCC2, l(2)SH2 2137, l(2)SH2137, MGC89573, TTD, XPD, xpd, XPD/ERCC2, zgc:56365Protein level used designations for ERCC2
- BTF2 p80
- CXPD
- DNA excision repair protein ERCC-2
- DNA repair protein complementing XP-D cells
- TFIIH 80 kDa subunit
- TFIIH basal transcription factor complex 80 kDa subunit
- TFIIH basal transcription factor complex helicase XPD subunit
- TFIIH basal transcription factor complex helicase subunit
- TFIIH p80
- basic transcription factor 2 80 kDa subunit
- xeroderma pigmentosum complementary group D
- xeroderma pigmentosum group D-complementing protein
- excision repair cross-complementing rodent repair deficiency, complementation group 2 (xeroderma pigmentosum D)
- excision repair cross-complementing rodent repair deficiency, complementation group 2 protein
- excision repair cross-complementing rodent repair deficiency, complementation group 2
- excision repair cross-complementing 2
- DNA-repair protein complementing XP-D cells
- excision repair cross-complementing rodent repair deficiency, complementation group 6-like group 2
- CG9433-PA
- CG9433-PB
- CG9433-PC
- Xpd-PA
- Xpd-PB
- Xpd-PC
- lethal (2) SH2137
- xeroderma pigmentosum D
- XPD
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