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Erythrocyte Ankyrin Produits

(Ankyrin 1, Erythrocytic (ANK1))

Catégories

Ankyrins are a family of proteins that link the integral membrane proteins to the underlying spectrin-actin cytoskeleton and play key roles in activities such as cell motility, activation, proliferation, contact and the maintenance of specialized membrane domains. Multiple isoforms of ankyrin with different affinities for various target proteins are expressed in a tissue-specific, developmentally regulated manner. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats\; a central region with a highly conserved spectrin binding domain\; and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. Ankyrin 1, the prototype of this family, was first discovered in the erythrocytes, but since has also been found in brain and muscles. Mutations in erythrocytic ankyrin 1 have been associated in approximately half of all patients with hereditary spherocytosis. Complex patterns of alternative splicing in the regulatory domain, giving rise to different isoforms of ankyrin 1 have been described. Truncated muscle-specific isoforms of ankyrin 1 resulting from usage of an alternate promoter have also been identified. [provided by RefSeq, Dec 2008].

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Catégories Erythrocyte Ankyrin en vedette

Erythrocyte Ankyrin Anticorps

High quality antibodies with extensive validation data.

Erythrocyte Ankyrin Kits ELISA

Reliable ELISA kits for a wide range of species.

Erythrocyte Ankyrin recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, ICC, IF
Validations
  • (3)
N° du produit ABIN2485521
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, ICC, IF
Validations
  • (3)
N° du produit ABIN2485534
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, ICC, IF
Validations
  • (3)
N° du produit ABIN2485533
Quantité 100 μg
Fiche technique Fiche technique

Erythrocyte Ankyrin recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6964879
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method
Validations
N° du produit ABIN1121977
Quantité 96 tests
Fiche technique Fiche technique

Erythrocyte Ankyrin recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1345068
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7416055
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits Erythrocyte Ankyrin

Tessema, Yingling, Picchi, Wu, Ryba, Lin, Bungum, Edell, Spira, Belinsky: "ANK1 Methylation regulates expression of MicroRNA-486-5p and discriminates lung tumors by histology and smoking status." dans: Cancer letters, Vol. 410, pp. 191-200, (2017) (PubMed).

Hall, Lu, Godfrey, Antonov, Paicu, Moxon, Dalmay, Wilczynska, Muller, Bushell: "The cytoskeleton adaptor protein ankyrin-1 is upregulated by p53 following DNA damage and alters cell migration." dans: Cell death & disease, Vol. 7, pp. e2184, (2016) (PubMed).

Wei, Cui, Huang, Zhang, Zhang, Hu: "Upregulated expression of cardiac ankyrin repeat protein in human failing hearts due to arrhythmogenic right ventricular cardiomyopathy." dans: European journal of heart failure, Vol. 11, Issue 6, pp. 559-66, (2009) (PubMed).

Dubreuil: "Functional links between membrane transport and the spectrin cytoskeleton." dans: The Journal of membrane biology, Vol. 211, Issue 3, pp. 151-61, (2006) (PubMed).

Synonymes et noms alternatifs relatifs à Erythrocyte Ankyrin

ankyrin 1 (ANK1), ankyrin 1, erythrocytic a (ank1a), ankyrin 1 (ank1), ankyrin 1 L homeolog (ank1.L), ankyrin 1, erythrocytic (ANK1), ankyrin 1 (Ank1), ankyrin 1, erythroid (Ank1), ank, ANK, Ank-1, ANK1, CHANK1, nb, pale, sph1, SPH1, sph2, SPH2, wu:fa09h06, zgc:101835

Protein level used designations for Erythrocyte Ankyrin

  • ankyrin 1, erythrocytic
  • erythroid ankyrin
  • ankyrin-1-like
  • ANK-1
  • ankyrin-1
  • ankyrin-R
  • erythrocyte ankyrin
  • ankyrin 1, erythroid
  • normoblastic anemia
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