ETV1 Produits
(Ets Variant 1 (ETV1))
Catégories
This gene encodes a member of the ETS (E twenty-six) family of transcription factors. The ETS proteins regulate many target genes that modulate biological processes like cell growth, angiogenesis, migration, proliferation and differentiation. All ETS proteins contain an ETS DNA-binding domain that binds to DNA sequences containing the consensus 5'-CGGA[AT]-3'. The protein encoded by this gene contains a conserved short acidic transactivation domain (TAD) in the N-terminal region, in addition to the ETS DNA-binding domain in the C-terminal region. This gene is involved in chromosomal translocations, which result in multiple fusion proteins including EWS-ETV1 in Erwing sarcoma and at least 10 ETV1 partners (see PMID: 19657377, Table 1) in prostate cancer. In addition to chromosomal rearrangement, this gene is overexpressed in prostate cancer, melanoma and gastrointestinal stromal tumor. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011].
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Catégories ETV1 en vedette
ETV1 Anticorps
High quality antibodies with extensive validation data.
ETV1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
ETV1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA
Validations
- (4)
N° du produit
ABIN560803
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
IHC, IF
Validations
- (4)
N° du produit
ABIN6140327
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA
Validations
- (1)
- (2)
N° du produit
ABIN969120
Quantité
100 μL
Fiche technique
Fiche technique
ETV1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN5648152
Quantité
96 tests
Fiche technique
Fiche technique
ETV1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1353176
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3079625
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3133992
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits ETV1
: "TMPRSS2-ERG gene fusion causing ERG overexpression precedes chromosome copy number changes in prostate carcinomas and paired HGPIN lesions." dans: Neoplasia (New York, N.Y.), Vol. 8, Issue 10, pp. 826-32, (2006) (PubMed).: "Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer." dans: Science (New York, N.Y.), Vol. 310, Issue 5748, pp. 644-8, (2005) (PubMed).
: "Dual requirement for gephyrin in glycine receptor clustering and molybdoenzyme activity." dans: Science (New York, N.Y.), Vol. 282, Issue 5392, pp. 1321-4, (1998) (PubMed).
: "Identification of a gephyrin binding motif on the glycine receptor beta subunit." dans: Neuron, Vol. 15, Issue 3, pp. 563-72, (1995) (PubMed).
: "Primary structure and alternative splice variants of gephyrin, a putative glycine receptor-tubulin linker protein." dans: Neuron, Vol. 8, Issue 6, pp. 1161-70, (1992) (PubMed).
Synonymes et noms alternatifs relatifs à ETV1
ETS variant 1 (etv1), ETS variant 1 (ETV1), ets variant 1 (Etv1), ETS variant 1 S homeolog (etv1.S), ets variant 1 (etv1), er81, ER81, Etsrp81, MGC75591, XER81Protein level used designations for ETV1
- ets variant 1
- ets domain protein
- ets variant gene 1
- ETS translocation variant 1
- ets-related protein 81
- ets-related transcription factor XER81
- ets related protein 81
- ETS transcription factor Er81
- er81
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