Factor VII Produits
(Coagulation Factor VII (F7))
Catégories
This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in this gene can cause coagulopathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012].
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Catégories Factor VII en vedette
Factor VII Anticorps
High quality antibodies with extensive validation data.
Factor VII Kits ELISA
Reliable ELISA kits for a wide range of species.
Factor VII Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
Factor VII recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (4)
N° du produit
ABIN7440011
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IP
Validations
- (3)
N° du produit
ABIN515448
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, PLA
Validations
- (3)
N° du produit
ABIN515449
Quantité
100 μg
Fiche technique
Fiche technique
Factor VII recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (6)
N° du produit
ABIN6574291
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (3)
N° du produit
ABIN6574292
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6963490
Quantité
96 tests
Fiche technique
Fiche technique
Factor VII recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1353322
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1353324
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7395107
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits Factor VII
: "Human acute Chagas disease: changes in factor VII, activated protein C and hepatic enzymes from patients of oral outbreaks in Pará State (Brazilian Amazon)." dans: Memórias do Instituto Oswaldo Cruz, Vol. 115, pp. e190364, (2020) (PubMed).: "Targeting Coagulation Factor Xa Promotes Regression of Advanced Atherosclerosis in Apolipoprotein-E Deficient Mice." dans: Scientific reports, Vol. 9, Issue 1, pp. 3909, (2019) (PubMed).
: "Loss of Sirt3 accelerates arterial thrombosis by increasing formation of neutrophil extracellular traps and plasma tissue factor activity." dans: Cardiovascular research, Vol. 114, Issue 8, pp. 1178-1188, (2018) (PubMed).
: "Ex vivo simulation of cardiopulmonary bypass with human blood for hemocompatibility testing." dans: Perfusion, Vol. 31, Issue 5, pp. 376-83, (2016) (PubMed).
: "TRUST trial: BAY 86-6150 use in haemophilia with inhibitors and assessment for immunogenicity." dans: Haemophilia : the official journal of the World Federation of Hemophilia, Vol. 22, Issue 6, pp. 873-879, (2016) (PubMed).
: "In vitro uptake of recombinant factor VIIa by megakaryocytes with subsequent production of platelets containing functionally active drug." dans: British journal of haematology, (2016) (PubMed).
: "Monocytes regulate systemic coagulation and inflammation in abdominal sepsis." dans: American journal of physiology. Heart and circulatory physiology, Vol. 308, Issue 5, pp. H540-7, (2015) (PubMed).
: "Coagulation factor VII is regulated by androgen receptor in breast cancer." dans: Experimental cell research, Vol. 331, Issue 1, pp. 239-50, (2015) (PubMed).
: "Novel antibody against a glutamic acid-rich human fibrinogen-like protein 2-derived peptide near Ser91 inhibits hfgl2 prothrombinase activity." dans: PLoS ONE, Vol. 9, Issue 4, pp. e94551, (2014) (PubMed).
: "Oestrogenic repression of human coagulation factor VII expression mediated through an oestrogen response element sequence motif in the promoter region." dans: Human molecular genetics, Vol. 11, Issue 7, pp. 723-31, (2002) (PubMed).
Synonymes et noms alternatifs relatifs à Factor VII
coagulation factor VII (F7), coagulation factor VII (f7), serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 (Serpinc1), coagulation factor VII (CpipJ_CPIJ009142), coagulation factor VII (CpipJ_CPIJ010295), coagulation factor VII (CpipJ_CPIJ020127), coagulation factor VII (fa7), coagulation factor 7 (serum prothrombin conversion accelerator) S homeolog (f7.S), AI114908, AI132620, At-3, At3, ATIII, Cf7, F7, f7, FVII, LOC100223776, mfVII, SPCA, wu:fb59f04, zgc:109870Protein level used designations for Factor VII
- coagulation factor VII
- serum prothrombin conversion accelerator
- clotting factor
- FVII coagulation protein
- eptacog alfa
- proconvertin
- anti-thrombin 3
- antithrombin
- antithrombin-III
- serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1
- serpin C1
- serpin peptidase inhibitor, clade C, member 1
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