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FAK Produits

(PTK2 Protein tyrosine Kinase 2 (PTK2))

Catégories

This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only three of them have been determined. [provided by RefSeq, Dec 2010].

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Catégories FAK en vedette

FAK Anticorps

High quality antibodies with extensive validation data.

FAK Kits ELISA

Reliable ELISA kits for a wide range of species.

FAK Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

FAK recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (3)
  • (8)
N° du produit ABIN6256730
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IF, IP
Validations
  • (1)
  • (7)
N° du produit ABIN6146423
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (7)
N° du produit ABIN7439699
Quantité 100 μL
Fiche technique Fiche technique

FAK recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6958990
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6969779
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6962403
Quantité 96 tests
Fiche technique Fiche technique

FAK recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (2)
N° du produit ABIN1316775
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7124708
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1316777
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits FAK

Kirschneck, Thuy, Leikam, Memmert, Deschner, Damanaki, Spanier, Proff, Jantsch, Schröder: "Role and Regulation of Mechanotransductive HIF-1α Stabilisation in Periodontal Ligament Fibroblasts." dans: International journal of molecular sciences, Vol. 21, Issue 24, (2021) (PubMed).

Mitra, Bhattacharyya, Alam, Sen, Mitra, Mandal, Vignesh, Majumder, Murmu: "Phosphorylation of EphA2 receptor and vasculogenic mimicry is an indicator of poor prognosis in invasive carcinoma of the breast." dans: Breast cancer research and treatment, Vol. 179, Issue 2, pp. 359-370, (2020) (PubMed).

Shen, Sun, Sun, Li, Wu, Li, Chen, Liu, Cui, Zhou: "ARRDC3 suppresses colorectal cancer progression through destabilizing the oncoprotein YAP." dans: FEBS letters, Vol. 592, Issue 4, pp. 599-609, (2019) (PubMed).

Rijal, Wang, Yu, Gang, Chen, Li: "Porcine Breast Extracellular Matrix Hydrogel for Spatial Tissue Culture." dans: International journal of molecular sciences, Vol. 19, Issue 10, (2019) (PubMed).

Yunes-Medina, Paciorkowski, Nuzbrokh, Johnson: "Depletion of transglutaminase 2 in neurons alters expression of extracellular matrix and signal transduction genes and compromises cell viability." dans: Molecular and cellular neurosciences, Vol. 86, pp. 72-80, (2018) (PubMed).

Zhang, Zhou, Meng, Zhang, Zhou: "Down-regulating Myoferlin inhibits the vasculogenic mimicry of melanoma via decreasing MMP-2 and inducing mesenchymal-to-epithelial transition." dans: Journal of cellular and molecular medicine, Vol. 22, Issue 3, pp. 1743-1754, (2018) (PubMed).

Wu, Wang, Fang, Huang, Sun, Xiao, Yan: "MFAP5 promotes tumor progression and bone metastasis by regulating ERK/MMP signaling pathways in breast cancer." dans: Biochemical and biophysical research communications, Vol. 498, Issue 3, pp. 495-501, (2018) (PubMed).

Huang, Song, Tao, Shao, Zeng, Xu, Qi, Sun: "Ovostatin 2 knockdown significantly inhibits the growth, migration, and tumorigenicity of cutaneous malignant melanoma cells." dans: PLoS ONE, Vol. 13, Issue 4, pp. e0195610, (2018) (PubMed).

Yang, Hu, Fan, Zhang, Zhong, Guo, Qin, Chen: "Picornavirus 2A protease regulates stress granule formation to facilitate viral translation." dans: PLoS pathogens, Vol. 14, Issue 2, pp. e1006901, (2018) (PubMed).

Shen, Cao, Wang, Ma, Zeng, Liu, Li, Tao, Gong, Xie: "Hippo component YAP promotes focal adhesion and tumour aggressiveness via transcriptionally activating THBS1/FAK signalling in breast cancer." dans: Journal of experimental & clinical cancer research : CR, Vol. 37, Issue 1, pp. 175, (2018) (PubMed).

Synonymes et noms alternatifs relatifs à FAK

protein tyrosine kinase 2 (PTK2), protein tyrosine kinase 2 L homeolog (ptk2.L), PTK2 protein tyrosine kinase 2 (PTK2), PTK2 protein tyrosine kinase 2 (Ptk2), protein tyrosine kinase 2ab (ptk2ab), protein tyrosine kinase 2 (Ptk2), Focal adhesion kinase (Fak), CG10023, CT28129, DFAK, DFak, Dfak, DFak56, Dfak56, Dmel\\CG10023, DmFAK, FADK, Fadk, FAK, fak, FAK1, fak1a, Fak56, fak56, Fak56D, FRNK, mKIAA4203, p125FAK, pp125FAK, PPP1R71, PTK2, ptk2, ptk2a, wu:fa18c04, zgc:66114

Protein level used designations for FAK

  • FADK 1
  • FAK-related non-kinase polypeptide
  • PTK2 protein tyrosine kinase 2
  • focal adhesion kinase 1
  • focal adhesion kinase-related nonkinase
  • protein phosphatase 1 regulatory subunit 71
  • protein phosphatase 1, regulatory subunit 71
  • focal adhesion kinase pp125FAK
  • pp125FAK
  • protein-tyrosine kinase 2
  • focal adhesion kinase
  • focal ashension kinase 1
  • p41/p43FRNK
  • faka
  • protein tyrosine kinase 2.1
  • CG10023-PA
  • CG10023-PB
  • CG10023-PC
  • CG10023-PD
  • CG10023-PF
  • CG10023-PG
  • Fak-PA
  • Fak-PB
  • Fak-PC
  • Fak-PD
  • Fak-PF
  • Fak-PG
  • focal adhesion kinase homolog
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