FANCA Produits
(Fanconi Anemia Group A Protein (FANCA))
Catégories
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity\; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group A. Alternative splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are the most common cause of Fanconi anemia. [provided by RefSeq, Jul 2008].
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Catégories FANCA en vedette
FANCA Anticorps
High quality antibodies with extensive validation data.
FANCA Kits ELISA
Reliable ELISA kits for a wide range of species.
FANCA Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
FANCA recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
- (2)
N° du produit
ABIN129606
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF, IHC (p), ICC
Validations
- (3)
N° du produit
ABIN2856901
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF
Validations
- (2)
N° du produit
ABIN515503
Quantité
50 μg
Fiche technique
Fiche technique
FANCA recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6966641
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Validations
N° du produit
ABIN1132955
Quantité
96 tests
Fiche technique
Fiche technique
FANCA recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1353621
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Baculovirus infected Insect Cells
Validations
N° du produit
ABIN7317446
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3092529
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits FANCA
: "The Fanconi anemia pathway has a dual function in Dickkopf-1 transcriptional repression." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 6, pp. 2152-7, (2014) (PubMed).: "Histone chaperone activity of Fanconi anemia proteins, FANCD2 and FANCI, is required for DNA crosslink repair." dans: The EMBO journal, Vol. 31, Issue 17, pp. 3524-36, (2012) (PubMed).
: "RAD18-mediated ubiquitination of PCNA activates the Fanconi anemia DNA repair network." dans: The Journal of cell biology, Vol. 191, Issue 2, pp. 249-57, (2011) (PubMed).
: "Differential roles for DNA polymerases eta, zeta, and REV1 in lesion bypass of intrastrand versus interstrand DNA cross-links." dans: Molecular and cellular biology, Vol. 30, Issue 5, pp. 1217-30, (2010) (PubMed).
: "Upregulated ATM gene expression and activated DNA crosslink-induced damage response checkpoint in Fanconi anemia: implications for carcinogenesis." dans: Molecular medicine (Cambridge, Mass.), Vol. 14, Issue 3-4, pp. 167-74, (2008) (PubMed).
: "Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair." dans: Cell, Vol. 129, Issue 2, pp. 289-301, (2007) (PubMed).
: "Oxidative stress/damage induces multimerization and interaction of Fanconi anemia proteins." dans: The Journal of biological chemistry, Vol. 279, Issue 29, pp. 30053-9, (2004) (PubMed).
Synonymes et noms alternatifs relatifs à FANCA
Fanconi anemia complementation group A (FANCA), Fanconi anemia, complementation group A (Fanca), AW208693, FA, FA-H, FA1, FAA, FACA, FAH, FANCHProtein level used designations for FANCA
- Fanconi anemia group A protein
- Fanconi anemia, complementation group H
- Fanconi anemia, type 1
- Fanconi anemia group A protein homolog
Avez-vous cherché autre chose?
- FAN1
- Family with Sequence Similarity 92, Member A1
- Family with Sequence Similarity 58, Member B
- Family with Sequence Similarity 50, Member A
- Family with Sequence Similarity 46, Member B
- Family with Sequence Similarity 220, Member A
- Family with Sequence Similarity 212, Member A
- Family with Sequence Similarity 102, Member B
- Family with Sequence Similarity 102, Member A
- FAM9C
- FAM9B
- FAM98C
- FAM98B
- FAM98A
- FAM96B
- FAM96A
- FAM92B
- FAM91A1
- Fam90a9
- Fam90a8
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