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Fascin Produits

(Fascin (FSCN1))
This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011].

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Catégories Fascin en vedette

Fascin Anticorps

High quality antibodies with extensive validation data.

Fascin Kits ELISA

Reliable ELISA kits for a wide range of species.

Fascin Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

Fascin recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, FACS, IF, StM
Validations
  • (7)
N° du produit ABIN6940607
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Rat
Application WB, IHC, FACS, IF, StM
Validations
  • (6)
N° du produit ABIN6940609
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse, Rat
Application WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (5)
N° du produit ABIN728293
Quantité 100 μL
Fiche technique Fiche technique

Fascin recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6955706
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Guinea Pig
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN776822
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rabbit
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN774867
Quantité 96 tests
Fiche technique Fiche technique

Fascin recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7122887
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1989775
Quantité 25 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN2129307
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits Fascin

Zhang, Zhao, Zhang, Hao, Yu, Min, Li, Ma, Chen, Yi, Tang, Meng, Liu, Wang, Shen, Zhang: "Decrease in male mouse fertility by hydrogen sulfide and/or ammonia can Be inheritable." dans: Chemosphere, Vol. 194, pp. 147-157, (2018) (PubMed).

Yang, Teng, Han, Li, Yue, Wang: "Clinical significance of fascin-1 and laminin-5 in non-small cell lung cancer." dans: Genetics and molecular research : GMR, Vol. 16, Issue 2, (2017) (PubMed).

Barnawi, Al-Khaldi, Majed Sleiman, Sarkar, Al-Dhfyan, Al-Mohanna, Ghebeh, Al-Alwan: "Fascin Is Critical for the Maintenance of Breast Cancer Stem Cell Pool Predominantly via the Activation of the Notch Self-Renewal Pathway." dans: Stem cells (Dayton, Ohio), Vol. 34, Issue 12, pp. 2799-2813, (2016) (PubMed).

Osanai, Lee: "The retinoic acid-metabolizing enzyme CYP26A1 upregulates fascin and promotes the malignant behavior of breast carcinoma cells." dans: Oncology reports, Vol. 34, Issue 2, pp. 850-8, (2015) (PubMed).

Król, Mucha, Majchrzak, Homa, Bulkowska, Majewska, Gajewska, Pietrzak, Perszko, Romanowska, Paw?owski, Manuali, Hellmen, Motyl: "Macrophages mediate a switch between canonical and non-canonical Wnt pathways in canine mammary tumors." dans: PLoS ONE, Vol. 9, Issue 1, pp. e83995, (2014) (PubMed).

Al-Masri, El Eter, Tayel, Zamil: "Differential associations of circulating peroxiredoxins levels with indicators of glycemic control in type 2 diabetes mellitus." dans: European review for medical and pharmacological sciences, Vol. 18, Issue 5, pp. 710-6, (2014) (PubMed).

Jiang, Wang, Chen: "Overexpression of FOXM1 is associated with metastases of nasopharyngeal carcinoma." dans: Upsala journal of medical sciences, Vol. 119, Issue 4, pp. 324-32, (2014) (PubMed).

Majchrzak, Lo Re, Gajewska, Bulkowska, Homa, Paw?owski, Motyl, Murphy, Król: "Migrastatin analogues inhibit canine mammary cancer cell migration and invasion." dans: PLoS ONE, Vol. 8, Issue 10, pp. e76789, (2013) (PubMed).

Teng, Xu, Yue, Ma, Zhang, Zhao, Guo, Zhang, Gu, Wang: "Serological investigation of the clinical significance of fascin in non-small-cell lung cancer." dans: Lung cancer (Amsterdam, Netherlands), Vol. 82, Issue 2, pp. 346-52, (2013) (PubMed).

Law, Li, Chou, Chen, Chan: "Hyaluronic acid-dependent protection in H9C2 cardiomyocytes: a cell model of heart ischemia-reperfusion injury and treatment." dans: Toxicology, Vol. 303, pp. 54-71, (2013) (PubMed).

Synonymes et noms alternatifs relatifs à Fascin

singed (sn), fascin actin-bundling protein 1 (fscn1), fascin actin-bundling protein 1a (fscn1a), fascin actin-bundling protein 1 (Fscn1), fascin actin-bundling protein 1 L homeolog (fscn1.L), fascin actin-bundling protein 1 (FSCN1), AI663989, CG1536, CG15331, CG32858, Dmel\\CG32858, Fan1, FAN1, Fascin, fascin, fascin-1, fs(1)A1057, fs(1)K418, fs(1)K473, fs(1)K743, fs(1)K1421, fs(1)M45, fscn, fscn1, HSN, MGC75811, p55, sb:cb589, SN, Sn, snl, SNL, zgc:153632

Protein level used designations for Fascin

  • CG32858-PA
  • CG32858-PB
  • CG32858-PD
  • CG32858-PE
  • CG32858-PF
  • CG32858-PG
  • fascin
  • sn-PA
  • sn-PB
  • sn-PD
  • sn-PE
  • sn-PF
  • sn-PG
  • fascin-1
  • fascin 1
  • singed-like protein
  • 55 kDa actin-bundling protein
  • singed-like (fascin homolog, sea urchin)
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