F13A1 Produits
(Coagulation Factor XIII, A1 Polypeptide (F13A1))
Catégories
This gene encodes the coagulation factor XIII A subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as plasma carrier molecules. Platelet factor XIII is comprised only of 2 A subunits, which are identical to those of plasma origin. Upon cleavage of the activation peptide by thrombin and in the presence of calcium ion, the plasma factor XIII dissociates its B subunits and yields the same active enzyme, factor XIIIa, as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules, thus stabilizing the fibrin clot. It also crosslinks alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin. Factor XIII deficiency is classified into two categories: type I deficiency, characterized by the lack of both the A and B subunits\; and type II deficiency, characterized by the lack of the A subunit alone. These defects can result in a lifelong bleeding tendency, defective wound healing, and habitual abortion. [provided by RefSeq, Jul 2008].
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Catégories F13A1 en vedette
F13A1 Anticorps
High quality antibodies with extensive validation data.
F13A1 Kits ELISA
Reliable ELISA kits for a wide range of species.
F13A1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
F13A1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (7)
N° du produit
ABIN7433159
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (10)
N° du produit
ABIN7442897
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (8)
N° du produit
ABIN7440509
Quantité
100 μL
Fiche technique
Fiche technique
F13A1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6965912
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6962106
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6954886
Quantité
96 tests
Fiche technique
Fiche technique
F13A1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1353305
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Human Cells
Validations
N° du produit
ABIN7319648
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7393214
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits F13A1
: "Localized papular mucinosis with IgA nephropathy: a case report." dans: Archives of dermatology, Vol. 147, Issue 5, pp. 599-602, (2011) (PubMed).: "Clinical significance of measuring blood coagulation factor XIIIA regularly and continuously in patients with Crohn's disease." dans: Journal of gastroenterology and hepatology, Vol. 21, Issue 9, pp. 1407-11, (2006) (PubMed).
: "The coagulation cascade: initiation, maintenance, and regulation." dans: Biochemistry, Vol. 30, Issue 43, pp. 10363-70, (1991) (PubMed).
Synonymes et noms alternatifs relatifs à F13A1
coagulation factor XIII A1 chain (F13a1), coagulation factor XIII, A1 polypeptide b (f13a1b), coagulation factor XIII A chain (F13A1), coagulation factor XIII, A1 subunit (F13a1), coagulation factor XIII A chain (F13a1), 1200014I03Rik, AI462306, F13a, F13A, f13a1, F13A1, wu:fo83d04, zgc:153334Protein level used designations for F13A1
- coagulation factor XIII A chain
- coagulation factor XIII, A1 subunit
- coagulation factor XIIIa
- protein-glutamine gamma-glutamyltransferase A chain
- transglutaminase A chain
- FX111a-87
- fo83d04
- coagulation factor XIII A1 subunit
- coagulation factor XIII, A1 polypeptide
- blood coagulation factor XIII A1 subunit
- coagulation factor XIIIA
- Coagulation factor XIII A chain
- FSF, A subunit
- TGase
- bA525O21.1 (coagulation factor XIII, A1 polypeptide)
- coagulation factor XIII, A polypeptide
- factor XIIIa
- fibrin stabilizing factor, A subunit
- fibrinoligase
- transglutaminase. plasma
- Factor XIIIA
- coagulation factor XIII, alpha subunit
- coagulation factor XIII A chain-like
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