FBXO32 Produits
(F-Box Protein 32 (FBXO32))
Catégories
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011].
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Catégories FBXO32 en vedette
FBXO32 Anticorps
High quality antibodies with extensive validation data.
FBXO32 Kits ELISA
Reliable ELISA kits for a wide range of species.
FBXO32 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
FBXO32 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB
Validations
- (5)
N° du produit
ABIN3017562
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC
Validations
- (3)
N° du produit
ABIN7251817
Quantité
200 μL
Fiche technique
Fiche technique
Reactivity
Human, Rat
Application
WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (1)
- (1)
N° du produit
ABIN747698
Quantité
100 μL
Fiche technique
Fiche technique
FBXO32 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6966624
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6966625
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6966626
Quantité
96 tests
Fiche technique
Fiche technique
FBXO32 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
N° du produit
ABIN1353808
Quantité
25 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7408129
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3128198
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits FBXO32
: "FBXO32 suppresses breast cancer tumorigenesis through targeting KLF4 to proteasomal degradation." dans: Oncogene, Vol. 36, Issue 23, pp. 3312-3321, (2017) (PubMed).: "Hindlimb Immobilization, But Not Castration, Induces Reduction of Undercarboxylated Osteocalcin Associated With Muscle Atrophy in Rats." dans: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 31, Issue 11, pp. 1967-1978, (2016) (PubMed).
: "Myostatin induces degradation of sarcomeric proteins through a Smad3 signaling mechanism during skeletal muscle wasting." dans: Molecular endocrinology (Baltimore, Md.), Vol. 25, Issue 11, pp. 1936-49, (2011) (PubMed).
: "The muscle-specific ubiquitin ligase atrogin-1/MAFbx mediates statin-induced muscle toxicity." dans: The Journal of clinical investigation, Vol. 117, Issue 12, pp. 3940-51, (2007) (PubMed).
Synonymes et noms alternatifs relatifs à FBXO32
F-box protein 32 (fbxo32), F-box protein 32 (FBXO32), F-box protein 32 (Fbxo32), 4833442G10Rik, AI430017, ATROGIN1, Atrogin1, Fbx32, Gm20361, MAFbx, MGC56479, zgc:56479Protein level used designations for FBXO32
- F-box only protein 32
- atrogin-1
- F-box protein 32
- F-box only protein 32-like
- atrogin 1
- muscle atrophy F-box protein
- atrophy gene 1
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