FBXW8 Produits
(F-Box and WD Repeat Domain Containing 8 (FBXW8))
Catégories
This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains a WD-40 domain, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].
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Catégories FBXW8 en vedette
FBXW8 Anticorps
High quality antibodies with extensive validation data.
FBXW8 Kits ELISA
Reliable ELISA kits for a wide range of species.
FBXW8 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
FBXW8 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse
Application
WB, FACS, IHC (p)
Validations
- (1)
- (4)
N° du produit
ABIN654676
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
- (2)
N° du produit
ABIN565252
Quantité
50 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, IHC (p), EIA
Validations
- (4)
N° du produit
ABIN952296
Quantité
0.4 mL
Fiche technique
Fiche technique
FBXW8 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
N° du produit
ABIN1743139
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Sheep
Analytical Method
Validations
N° du produit
ABIN1774044
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Dog
Analytical Method
Validations
N° du produit
ABIN1769148
Quantité
96 tests
Fiche technique
Fiche technique
FBXW8 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1353881
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3092555
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3136178
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits FBXW8
: "Both ubiquitin ligases FBXW8 and PARK2 are sequestrated into insolubility by ATXN2 PolyQ expansions, but only FBXW8 expression is dysregulated." dans: PLoS ONE, Vol. 10, Issue 3, pp. e0121089, (2015) (PubMed).: "The CUL7/F-box and WD repeat domain containing 8 (CUL7/Fbxw8) ubiquitin ligase promotes degradation of hematopoietic progenitor kinase 1." dans: The Journal of biological chemistry, Vol. 289, Issue 7, pp. 4009-17, (2014) (PubMed).
: "Effect of ursolic acid on MAPK in cyclin D1 signaling and RING-type E3 ligase (SCF E3s) in two endometrial cancer cell lines." dans: Nutrition and cancer, Vol. 65, Issue 7, pp. 1026-33, (2013) (PubMed).
: "Cullin 7 and Fbxw 8 expression in trophoblastic cells is regulated via oxygen tension: implications for intrauterine growth restriction?" dans: The journal of maternal-fetal & neonatal medicine, Vol. 25, Issue 11, pp. 2209-15, (2012) (PubMed).
: "Fbxw8 is involved in the proliferation of human choriocarcinoma JEG-3 cells." dans: Molecular biology reports, Vol. 38, Issue 3, pp. 1741-7, (2011) (PubMed).
: "A novel mechanism by which thiazolidinediones facilitate the proteasomal degradation of cyclin D1 in cancer cells." dans: The Journal of biological chemistry, Vol. 283, Issue 39, pp. 26759-70, (2008) (PubMed).
Synonymes et noms alternatifs relatifs à FBXW8
F-box and WD repeat domain containing 8 (FBXW8), F-box and WD repeat domain containing 8 (Fbxw8), ring finger protein, transmembrane 2 (RNFT2), F-box and WD-40 domain protein 8 (Fbxw8), 4930438M06Rik, FBW6, FBW8, FBX29, Fbx29, FBXO29, FBXW6Protein level used designations for FBXW8
- F-box and WD-40 domain protein 8
- F-box and WD-40 domain-containing protein 8
- F-box only protein 29
- F-box/WD repeat-containing protein 8
- F-box protein FBX29
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