Fc Receptor, IgG, Low Affinity IV Produits
(Fc Receptor, IgG, Low Affinity IV (FCGR4))
Catégories
Receptor for the Fc region of immunoglobulin gamma (PubMed:16039578). Also acts as a receptor for the Fc region of immunoglobulin epsilon (PubMed:17558411, PubMed:18949059). Binds with intermediate affinity to both IgG2a and IgG2b (PubMed:16039578, PubMed:17558411, PubMed:19795417). Can bind to IgG2a and IgG2b monomers (PubMed:18949059). Does not display binding to IgG1 or IgG3 (PubMed:16039578). Mediates neutrophil activation by IgG complexes redundantly with Fcgr3 (PubMed:18097064). Plays a role in promoting bone resorption by enhancing osteoclast differentiation following binding to IgG2a (PubMed:25824719). Binds with low affinity to both the a and b allotypes of IgE (PubMed:18949059). Has also been shown to bind to IgE allotype a only but not to allotype b (PubMed:17558411). Binds aggregated IgE but not the monomeric form and bound monomeric IgG is readily displaced by IgE complexes (PubMed:18949059). Binding to IgE promotes macrophage-mediated phagocytosis, antigen presentation to T cells, production of proinflammatory cytokines and the late phase of cutaneous allergic reactions (PubMed:17558411, PubMed:18949059). {ECO:0000269|PubMed:16039578, ECO:0000269|PubMed:17558411, ECO:0000269|PubMed:18097064, ECO:0000269|PubMed:18949059, ECO:0000269|PubMed:19795417, ECO:0000269|PubMed:25824719}.
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Catégories Fc Receptor, IgG, Low Affinity IV en vedette
Fc Receptor, IgG, Low Affinity IV Anticorps
High quality antibodies with extensive validation data.
Fc Receptor, IgG, Low Affinity IV Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
Fc Receptor, IgG, Low Affinity IV recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Application
FACS
Validations
- (1)
N° du produit
ABIN2664272
Quantité
100 μg
Fiche technique
Fiche technique
Fc Receptor, IgG, Low Affinity IV recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6730047
Quantité
96 tests
Fiche technique
Fiche technique
Fc Receptor, IgG, Low Affinity IV recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Source
Human Cells
Validations
N° du produit
ABIN7314672
Quantité
50 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits Fc Receptor, IgG, Low Affinity IV
: "Agonist anti-GITR monoclonal antibody and stereotactic radiation induce immune-mediated survival advantage in murine intracranial glioma." dans: Journal for immunotherapy of cancer, Vol. 4, pp. 28, (2016) (PubMed).: "Interaction with Fc?RIIB is critical for the agonistic activity of anti-CD40 monoclonal antibody." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 187, Issue 4, pp. 1754-63, (2011) (PubMed).
Synonymes et noms alternatifs relatifs à Fc Receptor, IgG, Low Affinity IV
Fc receptor, IgG, low affinity IV (Fcgr4), 4833442P21Rik, CD16-2, FcgammaRIV, Fcgr3a, FcgRIV, Fcrl3Protein level used designations for Fc Receptor, IgG, Low Affinity IV
- CD16-2
- Fc fragment of IgG, low affinity IIIa, receptor for (CD16); Fc fragment of IgG, low affinity III, receptor for (CD16)
- Fc gammaRIV
- Fc receptor-like 3
- FcgammaRIV
- low affinity immunoglobulin gamma Fc region receptor III-A
- low affinity immunoglobulin gamma Fc region receptor IV
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