FCAR Produits
(Fc Fragment of IgA, Receptor For (FCAR))
Catégories
This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].
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Catégories FCAR en vedette
FCAR Anticorps
High quality antibodies with extensive validation data.
FCAR Kits ELISA
Reliable ELISA kits for a wide range of species.
FCAR Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
FCAR recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, FACS, IHC, ICC, Neut
Validations
- (4)
N° du produit
ABIN5684138
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (3)
N° du produit
ABIN7443131
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Non-Human Primate
Application
FACS
Validations
- (2)
N° du produit
ABIN4888509
Quantité
0.1 mg
Fiche technique
Fiche technique
FCAR recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6955737
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN4882811
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Guinea Pig
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN776794
Quantité
96 tests
Fiche technique
Fiche technique
FCAR recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
N° du produit
ABIN7274249
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1353885
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Rat
Source
HEK-293 Cells
Validations
- (1)
N° du produit
ABIN7321241
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits FCAR
: "Complete Remission with Reduction of High-Risk Clones following Haploidentical NK-Cell Therapy against MDS and AML." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 24, Issue 8, pp. 1834-1844, (2018) (PubMed).: "Urinary myeloid IgA Fc alpha receptor (CD89) and transglutaminase-2 as new biomarkers for active IgA nephropathy and henoch-Schönlein purpura nephritis." dans: BBA clinical, Vol. 5, pp. 79-84, (2016) (PubMed).
: "Elevated Membrane and Soluble CD64: A Novel Marker Reflecting Altered Fc?R Function and Disease in Early Rheumatoid Arthritis That Can Be Regulated by Anti-Rheumatic Treatment." dans: PLoS ONE, Vol. 10, Issue 9, pp. e0137474, (2015) (PubMed).
: "Recognition and functional activation of the human IgA receptor (FcalphaRI) by C-reactive protein." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 12, pp. 4974-9, (2011) (PubMed).
: "Antigen binding to secretory immunoglobulin A results in decreased sensitivity to intestinal proteases and increased binding to cellular Fc receptors." dans: The Journal of biological chemistry, Vol. 285, Issue 2, pp. 953-60, (2010) (PubMed).
: "Intracellular pools of FcalphaR (CD89) in human neutrophils are localized in tertiary granules and secretory vesicles, and two FcalphaR isoforms are found in tertiary granules." dans: Journal of leukocyte biology, Vol. 82, Issue 3, pp. 551-8, (2007) (PubMed).
: "Neutrophil lactoferrin release induced by IgA immune complexes differed from that induced by cross-linking of fcalpha receptors (FcalphaR) with a monoclonal antibody, MIP8a." dans: Clinical and experimental immunology, Vol. 121, Issue 1, pp. 106-11, (2000) (PubMed).
Synonymes et noms alternatifs relatifs à FCAR
Fc fragment of IgA receptor (FCAR), Fc fragment of IgA, receptor for (FCAR), CD89Protein level used designations for FCAR
- IgA Fc receptor
- immunoglobulin A Fc receptor
- immunoglobulin alpha Fc receptor
- Fc fragment of IgA, receptor for, isoform 7
- Fc alpha receptor
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