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FEZ1 Produits

(Fasciculation and Elongation Protein zeta 1 (Zygin I) (FEZ1))

Catégories

This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Expression of this gene in C. elegans unc-76 mutants can restore to the mutants partial locomotion and axonal fasciculation, suggesting that it also functions in axonal outgrowth. The N-terminal half of the gene product is highly acidic. Alternatively spliced transcript variants encoding different isoforms of this protein have been described. [provided by RefSeq, Jul 2008].

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Catégories FEZ1 en vedette

FEZ1 Anticorps

High quality antibodies with extensive validation data.

FEZ1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

FEZ1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Rat
Application WB, ELISA, IHC
Validations
  • (3)
N° du produit ABIN185737
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (2)
N° du produit ABIN7152586
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB
Validations
  • (1)
  • (1)
N° du produit ABIN523131
Quantité 50 μg
Fiche technique Fiche technique

FEZ1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1353974
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7424329
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3080240
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits FEZ1

McKnight, Jefferies, Alemu, Saunders, Howell, Johansen, Tooze: "Genome-wide siRNA screen reveals amino acid starvation-induced autophagy requires SCOC and WAC." dans: The EMBO journal, Vol. 31, Issue 8, pp. 1931-46, (2012) (PubMed).

Kang, Burdick, Kim, Duan, Guo, Sailor, Jung, Ganesan, Choi, Pradhan, Lu, Avramopoulos, Christian, Malhotra, Song, Ming: "Interaction between FEZ1 and DISC1 in regulation of neuronal development and risk for schizophrenia." dans: Neuron, Vol. 72, Issue 4, pp. 559-71, (2011) (PubMed).

Hiraoka, Okumura, Kishimoto: "Turn motif phosphorylation negatively regulates activation loop phosphorylation in Akt." dans: Oncogene, Vol. 30, Issue 44, pp. 4487-97, (2011) (PubMed).

Blasius, Cai, Jih, Toret, Verhey: "Two binding partners cooperate to activate the molecular motor Kinesin-1." dans: The Journal of cell biology, Vol. 176, Issue 1, pp. 11-7, (2007) (PubMed).

Suzuki, Okada, Semba, Orba, Yamanouchi, Endo, Tanaka, Fujita, Kuroda, Nagashima, Sawa: "Identification of FEZ1 as a protein that interacts with JC virus agnoprotein and microtubules: role of agnoprotein-induced dissociation of FEZ1 from microtubules in viral propagation." dans: The Journal of biological chemistry, Vol. 280, Issue 26, pp. 24948-56, (2005) (PubMed).

Miyoshi, Honda, Baba, Taniguchi, Oono, Fujita, Kuroda, Katayama, Tohyama: "Disrupted-In-Schizophrenia 1, a candidate gene for schizophrenia, participates in neurite outgrowth." dans: Molecular psychiatry, Vol. 8, Issue 7, pp. 685-94, (2003) (PubMed).

Ishii, Baffa, Numata, Murakumo, Rattan, Inoue, Mori, Fidanza, Alder, Croce: "The FEZ1 gene at chromosome 8p22 encodes a leucine-zipper protein, and its expression is altered in multiple human tumors." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 7, pp. 3928-33, (1999) (PubMed).

Kuroda, Nakagawa, Tokunaga, Tatematsu, Tanizawa: "Mammalian homologue of the Caenorhabditis elegans UNC-76 protein involved in axonal outgrowth is a protein kinase C zeta-interacting protein." dans: The Journal of cell biology, Vol. 144, Issue 3, pp. 403-11, (1999) (PubMed).

Bloom, Horvitz: "The Caenorhabditis elegans gene unc-76 and its human homologs define a new gene family involved in axonal outgrowth and fasciculation." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 7, pp. 3414-9, (1997) (PubMed).

MacGrogan, Levy, Bova, Isaacs, Bookstein: "Structure and methylation-associated silencing of a gene within a homozygously deleted region of human chromosome band 8p22." dans: Genomics, Vol. 35, Issue 1, pp. 55-65, (1996) (PubMed).

Synonymes et noms alternatifs relatifs à FEZ1

fasciculation and elongation protein zeta 1 (FEZ1), fasciculation and elongation protein zeta 1 (zygin I) (Fez1), fasciculation and elongation protein zeta 1 (Fez1), fasciculation and elongation protein zeta 1 (zygin I) (fez1), fasciculation and elongation protein zeta 1 L homeolog (fez1.L), fez1, UNC-76, UNC76, wu:fj14c12, xfez1, zgc:73258

Protein level used designations for FEZ1

  • fasciculation and elongation protein zeta-1
  • zygin I
  • zygin-1
  • protein kinase C-binding protein Zeta1
  • zygin 1
  • fasciculation and elongation protein zeta 1 (zygin I)
  • fasciculation and elongation protein zeta 1 L homeolog
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