FGFR3 Produits
(Fibroblast Growth Factor Receptor 3 (FGFR3))
Catégories
This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia. Three alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, Jul 2009].
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Catégories FGFR3 en vedette
FGFR3 Anticorps
High quality antibodies with extensive validation data.
FGFR3 Kits ELISA
Reliable ELISA kits for a wide range of species.
FGFR3 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
FGFR3 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
ELISA, IHC, FACS
Validations
- (6)
N° du produit
ABIN5542298
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (5)
N° du produit
ABIN7434086
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IF
Validations
- (5)
N° du produit
ABIN1679839
Quantité
100 μg
Fiche technique
Fiche technique
FGFR3 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
N° du produit
ABIN6955879
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6966793
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6955880
Quantité
96 tests
Fiche technique
Fiche technique
FGFR3 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7122956
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1354043
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (1)
N° du produit
ABIN7320454
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits FGFR3
: "A comprehensive characterisation of large-scale expanded human bone marrow and umbilical cord mesenchymal stem cells." dans: Stem cell research & therapy, Vol. 10, Issue 1, pp. 99, (2019) (PubMed).: "The Neonatal and Adult Human Testis Defined at the Single-Cell Level." dans: Cell reports, Vol. 26, Issue 6, pp. 1501-1517.e4, (2019) (PubMed).
: "FGF23 is synthesised locally by renal tubules and activates injury-primed fibroblasts." dans: Scientific reports, Vol. 7, Issue 1, pp. 3345, (2018) (PubMed).
: "Stem cell and neurogenic gene-expression profiles link prostate basal cells to aggressive prostate cancer." dans: Nature communications, Vol. 7, pp. 10798, (2016) (PubMed).
: "FGFR2 regulates Mre11 expression and double-strand break repair via the MEK-ERK-POU1F1 pathway in breast tumorigenesis." dans: Human molecular genetics, Vol. 24, Issue 12, pp. 3506-17, (2015) (PubMed).
: "Biglycan is a novel binding partner of fibroblast growth factor receptor 3c (FGFR3c) in the human testis." dans: Molecular and cellular endocrinology, Vol. 399, pp. 235-43, (2014) (PubMed).
: "Selenium induces a multi-targeted cell death process in addition to ROS formation." dans: Journal of cellular and molecular medicine, Vol. 18, Issue 4, pp. 671-84, (2014) (PubMed).
: "Phenotype, donor age and gender affect function of human bone marrow-derived mesenchymal stromal cells." dans: BMC medicine, Vol. 11, pp. 146, (2013) (PubMed).
: "Identification of autocrine growth factors secreted by CHO cells for applications in single-cell cloning media." dans: Journal of proteome research, Vol. 12, Issue 7, pp. 3496-510, (2013) (PubMed).
: "Fibroblast growth factor-2 (Fgf2) is an important factor that maintains cellular immaturity and contributes to aggressiveness of osteosarcoma." dans: Molecular cancer research : MCR, (2012) (PubMed).
Synonymes et noms alternatifs relatifs à FGFR3
fibroblast growth factor receptor 3 (FGFR3), fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) S homeolog (fgfr3.S), fibroblast growth factor receptor 3 (Fgfr3), fibroblast growth factor receptor 3 (fgfr3), ACH, CD333, CEK2, fc27h01, Fgfr-3, FGFR3, Flg-2, FR3, HBGFR, HSFGFR3EX, JTK4, LOC100034114, Mfr3, sam3, wu:fc27h01Protein level used designations for FGFR3
- fibroblast growth factor receptor 3
- FGFR-3
- fibroblast growth factor receptor 3 variant 4
- hydroxyaryl-protein kinase
- tyrosine kinase JTK4
- heparin-binding growth factor receptor
- fibroblast growth factor receptor 3-IIIc
- tyrosine kinase (cek2)
- tyrosine kinase receptor CEK2
- fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism)
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