Fgr Produits
(Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR))
Catégories
This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008].
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Catégories Fgr en vedette
Fgr Anticorps
High quality antibodies with extensive validation data.
Fgr Kits ELISA
Reliable ELISA kits for a wide range of species.
Fgr Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
Fgr recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC (p), IF
Validations
- (2)
- (5)
N° du produit
ABIN392096
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (6)
N° du produit
ABIN560883
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (3)
N° du produit
ABIN7174020
Quantité
100 μg
Fiche technique
Fiche technique
Fgr recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
N° du produit
ABIN4886105
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN4882882
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6385940
Quantité
96 tests
Fiche technique
Fiche technique
Fgr recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1354064
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1354066
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
N° du produit
ABIN2721125
Quantité
20 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits Fgr
: "Unique-region phosphorylation targets LynA for rapid degradation, tuning its expression and signaling in myeloid cells." dans: eLife, Vol. 8, (2020) (PubMed).: "Src family kinase expression and subcellular localization in macrophages: implications for their role in CSF-1-induced macrophage migration." dans: Journal of leukocyte biology, Vol. 100, Issue 1, pp. 163-75, (2016) (PubMed).
: "LynA regulates an inflammation-sensitive signaling checkpoint in macrophages." dans: eLife, Vol. 4, (2016) (PubMed).
: "High-throughput RNAi screening identifies a role for TNK1 in growth and survival of pancreatic cancer cells." dans: Molecular cancer research : MCR, Vol. 9, Issue 6, pp. 724-32, (2011) (PubMed).
: "SRC family kinase activity is up-regulated in hormone-refractory prostate cancer." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 15, Issue 10, pp. 3540-9, (2009) (PubMed).
: "Coactivator assembly at the promoter: efficient recruitment of SRC2 is coupled to cooperative DNA binding by the progesterone receptor." dans: Biochemistry, Vol. 46, Issue 39, pp. 11023-32, (2007) (PubMed).
: "The Src family kinases Hck and Fgr negatively regulate neutrophil and dendritic cell chemokine signaling via PIR-B." dans: Immunity, Vol. 22, Issue 2, pp. 235-46, (2005) (PubMed).
: "Inhibition of receptor-dependent urokinase signaling by specific Ser to Glu substitutions." dans: Biological chemistry, Vol. 383, Issue 1, pp. 107-13, (2002) (PubMed).
: "Expression of the retinoblastoma protein is regulated in normal human tissues." dans: The American journal of pathology, Vol. 144, Issue 3, pp. 500-10, (1994) (PubMed).
: "The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest." dans: Cell, Vol. 79, Issue 1, pp. 119-30, (1994) (PubMed).
Synonymes et noms alternatifs relatifs à Fgr
FGR proto-oncogene, Src family tyrosine kinase (FGR), FGR proto-oncogene, Src family tyrosine kinase (Fgr), c-fgr, c-src2, p55-Fgr, p55c-fgr, p58-Fgr, p58c-fgr, SRC2Protein level used designations for Fgr
- Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
- c-fgr protooncogene
- c-src-2 proto-oncogene
- p55-c-fgr protein
- proto-oncogene c-Fgr
- proto-oncogene tyrosine-protein kinase FGR
- tyrosine-protein kinase Fgr
- v-fgr feline Gardner-Rasheed sarcoma viral oncogene homolog
- Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog
- proto-oncogene tyrosine-protein kinase Fgr
- tyrosine-protein kinase Fgr-like
- p55-Fgr
- feline Gardner-Rasheed sarcoma viral oncogene homolog
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