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FH Produits

(Fumarate Hydratase (FH))
The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy. [provided by RefSeq, Jul 2008].

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Catégories FH en vedette

FH Anticorps

High quality antibodies with extensive validation data.

FH Kits ELISA

Reliable ELISA kits for a wide range of species.

FH Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

FH recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (6)
N° du produit ABIN7444424
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IF, IHC (p), ICC
Validations
  • (1)
  • (5)
N° du produit ABIN2856710
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Dog, Human, Rat
Application WB, IHC, IF, IHC (p), FACS
Validations
  • (7)
N° du produit ABIN1498267
Quantité 100 μL
Fiche technique Fiche technique

FH recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6966911
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN770784
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Guinea Pig
Analytical Method Quantitative
Validations
N° du produit ABIN776853
Quantité 96 tests
Fiche technique Fiche technique

FH recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN666730
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1354068
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7418329
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits FH

Zhou, Xu, Zeng, Chen, Lu, Gong, Finnell, Xiao, Qiao, Wang: "Combined effects of FH (E404D) and ACOX2 (R409H) cause metabolic defects in primary cardiac malignant tumor." dans: Cell death discovery, Vol. 4, pp. 18, (2018) (PubMed).

Miettinen, Felisiak-Golabek, Wasag, Chmara, Wang, Butzow, Lasota: "Fumarase-deficient Uterine Leiomyomas: An Immunohistochemical, Molecular Genetic, and Clinicopathologic Study of 86 Cases." dans: The American journal of surgical pathology, Vol. 40, Issue 12, pp. 1661-1669, (2017) (PubMed).

Burkart, Tan, Warren, Iovino, Hughes, Kahn, Patti: "Insulin Resistance in Human iPS Cells Reduces Mitochondrial Size and Function." dans: Scientific reports, Vol. 6, pp. 22788, (2016) (PubMed).

Xu, Ge, Huo, Zhang, Lau, Xu: "Differential proteomic expression of human placenta and fetal development following e-waste lead and cadmium exposure in utero." dans: The Science of the total environment, Vol. 550, pp. 1163-1170, (2016) (PubMed).

Kratochvílová, Hejzlarová, Vrbacký, Mrá?ek, Karbanová, Tesa?ová, Gombitová, Cmarko, Wittig, Zeman, Houšt?k: "Mitochondrial membrane assembly of TMEM70 protein." dans: Mitochondrion, Vol. 15, pp. 1-9, (2014) (PubMed).

Kov?ová, Mrá?ek, N?sková, Holzerová, Vrbacký, Pecina, Hejzlarová, K?u?ková, Rohlena, Neuzil, Houšt?k: "High molecular weight forms of mammalian respiratory chain complex II." dans: PLoS ONE, Vol. 8, Issue 8, pp. e71869, (2013) (PubMed).

Burté, De Girolamo, Hargreaves, Billett: "Alterations in the mitochondrial proteome of neuroblastoma cells in response to complex 1 inhibition." dans: Journal of proteome research, Vol. 10, Issue 4, pp. 1974-86, (2011) (PubMed).

Pollard, Spencer-Dene, Shukla, Howarth, Nye, El-Bahrawy, Deheragoda, Joannou, McDonald, Martin, Igarashi, Varsani-Brown, Rosewell, Poulsom, Maxwell, Stamp, Tomlinson: "Targeted inactivation of fh1 causes proliferative renal cyst development and activation of the hypoxia pathway." dans: Cancer cell, Vol. 11, Issue 4, pp. 311-9, (2007) (PubMed).

Synonymes et noms alternatifs relatifs à FH

fumarate hydratase (FH), fumarate hydratase (fumH), fumarate hydratase (Fh), fumarate hydratase (fh), fumarate hydratase 1 (Fh1), DDBDRAFT_0205237, DDBDRAFT_0231397, DDBDRAFT_0231400, DDB_0205237, DDB_0231397, DDB_0231400, FH, Fh, Fh-1, Fh1, HLRCC, im:7152785, LRCC, MCL, MCUL1, ns:zf-e152, zf-e152, zgc:66253, zgc:77498

Protein level used designations for FH

  • fumarate hydratase, mitochondrial
  • fumarate hydratase
  • fumarase
  • fumarate hydratase 1
  • EF-3
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