Fibroblast Growth Factor Receptor Produits
(Fibroblast Growth Factor Receptor (FGFR))
Catégories
Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required for normal mesoderm patterning and normal skeletogenesis. Phosphorylates PLCG1, FRS2, GAB1 and SHB. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol- 1,4,5-trisphosphate. Phosphorylation of FRS2 triggers recruitment of GRB2, GAB1, PIK3R1 and SOS1, and mediates activation of RAS, MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling pathway, as well as of the AKT1 signaling pathway. Promotes phosphorylation of SHC1, STAT1 and PTPN11/SHP2. In the nucleus, enhances RPS6KA1 and CREB1 activity and contributes to the regulation of transcription. FGFR1 signaling is down-regulated by ubiquitination, internalization and degradation (By similarity).
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Catégories Fibroblast Growth Factor Receptor en vedette
Fibroblast Growth Factor Receptor Anticorps
High quality antibodies with extensive validation data.
Fibroblast Growth Factor Receptor Kits ELISA
Reliable ELISA kits for a wide range of species.
Fibroblast Growth Factor Receptor recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB
Validations
N° du produit
ABIN2267319
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB
Validations
N° du produit
ABIN2267321
Quantité
1 mg
Fiche technique
Fiche technique
Fibroblast Growth Factor Receptor recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Pig
Analytical Method
Quantitative Competition ELISA
Validations
N° du produit
ABIN778747
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Goat
Analytical Method
Quantitative Competition ELISA
Validations
N° du produit
ABIN989383
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Cow
Analytical Method
Quantitative Competition ELISA
Validations
N° du produit
ABIN989385
Quantité
96 tests
Fiche technique
Fiche technique
Fibroblast Growth Factor Receptor recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Sea Squirt
Source
Yeast
Validations
N° du produit
ABIN1628579
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Hydra
Source
Yeast
Validations
N° du produit
ABIN1623910
Quantité
1 mg
Fiche technique
Fiche technique
Synonymes et noms alternatifs relatifs à Fibroblast Growth Factor Receptor
heartless (htl), fibroblast growth factor receptor 1 L homeolog (fgfr1.L), fibroblast growth factor receptor (FGFR), fibroblast growth factor receptor 1 S homeolog (fgfr1.S), fibroblast growth factor receptor (fgfr), fibroblast growth factor receptor 1 (FGFR1), fibroblast growth factor receptor 1 (fgfr1), fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) L homeolog (fgfr3.L), basic fibroblast growth factor receptor 1 (CpipJ_CPIJ005849), ach, bfgfr, cd331, cd333, cek, cek2, CG7223, CT22273, CT39172, DFGF-R1, DFGF-R2, DFR-1, Dfr-1, DFR1, Dfr1, DFR1/DFGF-R2, Dmel\\CG7223, DmHD-38, DPR3, Dtk1, dtk1, DTRK(FR1), EMS2, FGF-R2, fgfbr, FGFR, fgfr, fgfr-1, fgfr-3, fgfr1, FGFR2, flg, FLG-1, flt-2, flt2, FR1, Fr1, hbgfr, HD-38, hsfgfr3ex, Htl, HTL/FGFR1, i79, i100, i150, j372, jtk4, kal2, n-sam, ogd, Tk1, x1fgfr, X1FGFR, XFGFR-1, xfgfr1, XFGFRA2Protein level used designations for Fibroblast Growth Factor Receptor
- CG7223-PA
- CG7223-PB
- CG7223-PC
- FGF receptor
- fibroblast growth factor receptor
- fibroblast growth factor receptor 1
- htl-PA
- htl-PB
- htl-PC
- FGFR-1
- fibroblast growth factor receptor-1
- fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome)
- ibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome)
- basic fibroblast growth factor receptor 1
- basic fibroblast growth factor receptor 1-like
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