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Filamin A Produits

(Filamin A, alpha (FLNA))
The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009].

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Catégories Filamin A en vedette

Filamin A Anticorps

High quality antibodies with extensive validation data.

Filamin A Kits ELISA

Reliable ELISA kits for a wide range of species.

Filamin A Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

Filamin A recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (7)
N° du produit ABIN7440788
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application IHC, IF
Validations
  • (6)
N° du produit ABIN7259092
Quantité 200 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC (p), PLA
Validations
  • (8)
  • (5)
N° du produit ABIN560922
Quantité 100 μg
Fiche technique Fiche technique

Filamin A recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6955914
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN1381139
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN512498
Quantité 96 tests
Fiche technique Fiche technique

Filamin A recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1354202
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
  • (1)
N° du produit ABIN2721188
Quantité 20 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7412995
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits Filamin A

Justa-Schuch, Silva-Garcia, Pilla, Engelke, Kilisch, Lenz, Möller, Nakamura, Urlaub, Geiss-Friedlander: "DPP9 is a novel component of the N-end rule pathway targeting the tyrosine kinase Syk." dans: eLife, Vol. 5, (2016) (PubMed).

Zhao, Ma, Hu, Zang, Tian, Zhang: "Filamin A (FLNA) modulates chemosensitivity to docetaxel in triple-negative breast cancer through the MAPK/ERK pathway." dans: Tumour biology, Vol. 37, Issue 4, pp. 5107-15, (2016) (PubMed).

Mingione, Verdelli, Ferrero, Vaira, Guarnieri, Scillitani, Vicentini, Balza, Beretta, Terranegra, Vezzoli, Soldati, Corbetta: "Filamin A is reduced and contributes to the CASR sensitivity in human parathyroid tumors." dans: Journal of molecular endocrinology, Vol. 58, Issue 2, pp. 91-103, (2016) (PubMed).

Parrini, Mei, Pisanti, Catarzi, Pucatti, Bianchini, Mascalchi, Bertini, Morrone, Cavaliere, Guerrini: "Familial periventricular nodular heterotopia, epilepsy and Melnick-Needles Syndrome caused by a single FLNA mutation with combined gain-of-function and loss-of-function effects." dans: Journal of medical genetics, Vol. 52, Issue 6, pp. 405-12, (2015) (PubMed).

Bézie, Picarda, Tesson, Renaudin, Durand, Ménoret, Mérieau, Chiffoleau, Guillonneau, Caron, Anegon: "Fibrinogen-like protein 2/fibroleukin induces long-term allograft survival in a rat model through regulatory B cells." dans: PLoS ONE, Vol. 10, Issue 3, pp. e0119686, (2015) (PubMed).

Campos, Rodriguez, Machado Leopoldino, Hait, Lopez Bergami, Castro, Sanchez, Maceyka, Spiegel, Alvarez: "Filamin A Expression Negatively Regulates Sphingosine-1-Phosphate-Induced NF-?B Activation in Melanoma Cells by Inhibition of Akt Signaling." dans: Molecular and cellular biology, (2015) (PubMed).

Henkels, Mallets, Dennis, Gomez-Cambronero: "S6K is a morphogenic protein with a mechanism involving Filamin-A phosphorylation and phosphatidic acid binding." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 29, Issue 4, pp. 1299-313, (2015) (PubMed).

Peverelli, Giardino, Treppiedi, Vitali, Cambiaghi, Locatelli, Lasio, Spada, Lania, Mantovani: "Filamin A (FLNA) plays an essential role in somatostatin receptor 2 (SST2) signaling and stabilization after agonist stimulation in human and rat somatotroph tumor cells." dans: Endocrinology, Vol. 155, Issue 8, pp. 2932-41, (2014) (PubMed).

Oegema, Hulst, Theuns-Valks, van Unen, Schot, Mancini, Schipper, de Wit, Sibbles, de Coo, Nanninga, Hofstra, Halley, Brooks: "Novel no-stop FLNA mutation causes multi-organ involvement in males." dans: American journal of medical genetics. Part A, Vol. 161A, Issue 9, pp. 2376-84, (2013) (PubMed).

Sakane, Alamir Mahmoud Abdallah, Nakano, Honda, Kitamura, Imoto, Matsushita, Sasaki: "Junctional Rab13-binding protein (JRAB) regulates cell spreading via filamins." dans: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 18, Issue 9, pp. 810-22, (2013) (PubMed).

Synonymes et noms alternatifs relatifs à Filamin A

filamin A (FLNA), filamin A, alpha (actin binding protein 280) (flna), filamin, alpha (Flna), filamin A (Flna), filamin-A (LOC587317), filamin A (flna), cheerio (cher), filamin-A (LOC100380643), ABP-280, ABPX, CG3937, Cher, CSBS, CVD1, Dilp2, Dmel\\CG3937, F730004A14Rik, fb98b06, Fil, filamin-1, FLN, FLN-A, FLN1, Fln1, FMD, joy, MGC147094, MNS, NHBP, OPD, OPD1, OPD2, RGD1560614, sko, wu:fb98b06, wu:fd09g03, wu:fd49a06, XLVD, XMVD

Protein level used designations for Filamin A

  • actin binding protein 280
  • alpha-filamin
  • endothelial actin-binding protein
  • filamin-1
  • filamin-A
  • non-muscle filamin
  • filamin A, alpha (actin binding protein 280)
  • fd09g03
  • FLN-A
  • GENA 379
  • actin-binding protein 280
  • dilated pupils 2
  • filamin A
  • Endothelial actin-binding protein 280)
  • filamin, alpha
  • filamin A, alpha
  • CG3937-PA
  • CG3937-PB
  • CG3937-PF
  • CG3937-PG
  • CG3937-PH
  • CG3937-PI
  • CG3937-PK
  • CG3937-PL
  • CG3937-PM
  • CG3937-PN
  • Filamin-1
  • Filamin-A
  • cher-PA
  • cher-PB
  • cher-PF
  • cher-PG
  • cher-PH
  • cher-PI
  • cher-PK
  • cher-PL
  • cher-PM
  • cher-PN
  • filamin
  • filamin B
  • filamin isoform B
  • filamin-240
  • shi kong
  • 450 kDa protein
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