FLIP Produits
(CASP8 and FADD-Like Apoptosis Regulator (CFLAR))
Catégories
The protein encoded by this gene is a regulator of apoptosis and is structurally similar to caspase-8. However, the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase-8. Several transcript variants encoding different isoforms have been found for this gene, and partial evidence for several more variants exists. [provided by RefSeq, Feb 2011].
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Catégories FLIP en vedette
FLIP Anticorps
High quality antibodies with extensive validation data.
FLIP Kits ELISA
Reliable ELISA kits for a wide range of species.
FLIP Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
FLIP recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, FACS
Validations
- (2)
- (6)
N° du produit
ABIN1724850
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC (p), IF
Validations
- (7)
N° du produit
ABIN563829
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (4)
N° du produit
ABIN7146901
Quantité
100 μg
Fiche technique
Fiche technique
FLIP recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6965446
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6954407
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6213279
Quantité
96 tests
Fiche technique
Fiche technique
FLIP recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1349226
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN935116
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1349225
Quantité
25 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits FLIP
: "Caspase-1 Engagement and TLR-Induced c-FLIP Expression Suppress ASC/Caspase-8-Dependent Apoptosis by Inflammasome Sensors NLRP1b and NLRC4." dans: Cell reports, Vol. 21, Issue 12, pp. 3427-3444, (2018) (PubMed).: "The TRAIL-Induced Cancer Secretome Promotes a Tumor-Supportive Immune Microenvironment via CCR2." dans: Molecular cell, Vol. 65, Issue 4, pp. 730-742.e5, (2017) (PubMed).
: "Identification of novel molecular regulators of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in breast cancer cells by RNAi screening." dans: Breast cancer research : BCR, Vol. 16, Issue 2, pp. R41, (2014) (PubMed).
: "RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis." dans: Nature, Vol. 513, Issue 7516, pp. 90-4, (2014) (PubMed).
: "Poor antibody validation is a challenge in biomedical research: a case study for detection of c-FLIP." dans: Apoptosis : an international journal on programmed cell death, Vol. 18, Issue 10, pp. 1154-62, (2013) (PubMed).
: "Release of an ~55kDa fragment containing the actin-binding domain of ?-spectrin by caspase-8 during FND-induced apoptosis depends on the presence of protein 4.1." dans: Archives of biochemistry and biophysics, Vol. 535, Issue 2, pp. 205-13, (2013) (PubMed).
: "Expression of c-FLIP in pulmonary metastases in osteosarcoma patients and human xenografts." dans: Pediatric blood & cancer, Vol. 60, Issue 4, pp. 575-9, (2013) (PubMed).
: "Predictive value of Sp1/Sp3/FLIP signature for prostate cancer recurrence." dans: PLoS ONE, Vol. 7, Issue 9, pp. e44917, (2012) (PubMed).
: "The novel Akt inhibitor API-1 induces c-FLIP degradation and synergizes with TRAIL to augment apoptosis independent of Akt inhibition." dans: Cancer prevention research (Philadelphia, Pa.), Vol. 5, Issue 4, pp. 612-20, (2012) (PubMed).
: "CHOP down-regulates cFLIP(L) expression by promoting ubiquitin/proteasome-mediated cFLIP(L) degradation." dans: Journal of cellular biochemistry, Vol. 113, Issue 12, pp. 3692-700, (2012) (PubMed).
Synonymes et noms alternatifs relatifs à FLIP
CASP8 and FADD-like apoptosis regulator a (cflara), CASP8 and FADD like apoptosis regulator (CFLAR), CASP8 and FADD like apoptosis regulator (cflar), CASP8 and FADD like apoptosis regulator S homeolog (cflar.S), CASP8 and FADD-like apoptosis regulator (Cflar), 2310024N18Rik, A430105C05Rik, c-FLIP, c-Flip, c-FLIPL, c-FLIPR, c-FLIPS, CASH, Cash, CASP8AP1, Casper, cflar, CFLAR, CLARP, Clarp1, ENSMUSG00000072980, FLAME, FLAME-1, FLAME1, FLIP, Flip, Gm9845, I-FLICE, MRITProtein level used designations for FLIP
- FLIP
- CASP8 and FADD-like apoptosis regulator
- flice/caspase-i inhibitory protein
- cellular FLICE-like inhibitory protein
- CASP8 and FADD-like apoptosis regulator-like
- FADD-like anti-apoptotic molecule
- FADD-like antiapoptotic molecule 1
- MACH-related inducer of toxicity
- caspase homolog
- caspase-eight-related protein
- caspase-like apoptosis regulatory protein
- caspase-related inducer of apoptosis
- inhibitor of FLICE
- usurpin beta
- usurpin
- FLICE-like inhibitory protein
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