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FLNC Produits

(Filamin C, gamma (FLNC))
This gene encodes one of three related filamin genes, specifically gamma filamin. These filamin proteins crosslink actin filaments into orthogonal networks in cortical cytoplasm and participate in the anchoring of membrane proteins for the actin cytoskeleton. Three functional domains exist in filamin: an N-terminal filamentous actin-binding domain, a C-terminal self-association domain, and a membrane glycoprotein-binding domain. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Catégories FLNC en vedette

FLNC Anticorps

High quality antibodies with extensive validation data.

FLNC Kits ELISA

Reliable ELISA kits for a wide range of species.

FLNC Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

FLNC recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (7)
N° du produit ABIN7441958
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (2)
  • (2)
N° du produit ABIN560923
Quantité 50 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (2)
N° du produit ABIN7435937
Quantité 100 μL
Fiche technique Fiche technique

FLNC recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6955916
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Guinea Pig
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN776808
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rabbit
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN774853
Quantité 96 tests
Fiche technique Fiche technique

FLNC recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1354206
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7505105
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7413877
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits FLNC

Kiselev, Vaz, Knyazeva, Khudiakov, Tarnovskaya, Liu, Sergushichev, Kazakov, Frishman, Smolina, Pervunina, Jorholt, Sjoberg, Vershinina, Rudenko, Arner, Sejersen, Lindstrand, Kostareva: "De novo mutations in FLNC leading to early-onset restrictive cardiomyopathy and congenital myopathy." dans: Human mutation, Vol. 39, Issue 9, pp. 1161-1172, (2018) (PubMed).

Reinstein, Gutierrez-Fernandez, Tzur, Bormans, Marcu, Tayeb-Fligelman, Vinkler, Raas-Rothschild, Irge, Landau, Shohat, Puente, Behar, Lopez-Otın: "Congenital dilated cardiomyopathy caused by biallelic mutations in Filamin C." dans: European journal of human genetics : EJHG, Vol. 24, Issue 12, pp. 1792-1796, (2016) (PubMed).

Begay, Tharp, Martin, Graw, Sinagra, Miani, Sweet, Slavov, Stafford, Zeller, Alnefaie, Rowland, Brun, Jones, Gowan, Mestroni, Garrity, Taylor: "FLNC Gene Splice Mutations Cause Dilated Cardiomyopathy." dans: JACC. Basic to translational science, Vol. 1, Issue 5, pp. 344-359, (2016) (PubMed).

Valdés-Mas, Gutiérrez-Fernández, Gómez, Coto, Astudillo, Puente, Reguero, Álvarez, Morís, León, Martín, Puente, López-Otín: "Mutations in filamin C cause a new form of familial hypertrophic cardiomyopathy." dans: Nature communications, Vol. 5, pp. 5326, (2014) (PubMed).

Kentsis, Shulman, Ahmed, Brennan, Monuteaux, Lee, Lipsett, Paulo, Dedeoglu, Fuhlbrigge, Bachur, Bradwin, Arditi, Sundel, Newburger, Steen, Kim: "Urine proteomics for discovery of improved diagnostic markers of Kawasaki disease." dans: EMBO molecular medicine, Vol. 5, Issue 2, pp. 210-20, (2013) (PubMed).

Sakane, Alamir Mahmoud Abdallah, Nakano, Honda, Kitamura, Imoto, Matsushita, Sasaki: "Junctional Rab13-binding protein (JRAB) regulates cell spreading via filamins." dans: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 18, Issue 9, pp. 810-22, (2013) (PubMed).

Tsuchiya, Iseda, Hino: "Identification of a novel protein (VBP-1) binding to the von Hippel-Lindau (VHL) tumor suppressor gene product." dans: Cancer research, Vol. 56, Issue 13, pp. 2881-5, (1996) (PubMed).

Sharma, Ezzell, Arnaout: "Direct interaction of filamin (ABP-280) with the beta 2-integrin subunit CD18." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 154, Issue 7, pp. 3461-70, (1995) (PubMed).

Price, Caprette, Gomer: "Different temporal patterns of expression result in the same type, amount, and distribution of filamin (ABP) in cardiac and skeletal myofibrils." dans: Cell motility and the cytoskeleton, Vol. 27, Issue 3, pp. 248-61, (1994) (PubMed).

Patrosso, Repetto, Villa, Milanesi, Frattini, Faranda, Mancini, Maestrini, Toniolo, Vezzoni: "The exon-intron organization of the human X-linked gene (FLN1) encoding actin-binding protein 280." dans: Genomics, Vol. 21, Issue 1, pp. 71-6, (1994) (PubMed).

Synonymes et noms alternatifs relatifs à FLNC

filamin C (FLNC), filamin C L homeolog (flnc.L), filamin C (flnc), filamin C, gamma (Flnc), filamin C (Flnc), 1110055E19Rik, ABP-280, ABP280A, ABPA, ABPL, Fln2, FLN2, MFM5, MPD4

Protein level used designations for FLNC

  • filamin C, gamma (actin binding protein 280)
  • gamma filamin
  • filamin C, gamma
  • filamin-C-like
  • ABP-280-like protein
  • ABP-L
  • FLN-C
  • actin binding protein 280
  • actin-binding protein 280
  • actin-binding-like protein
  • filamin, gamma
  • filamin-2
  • filamin-C
  • gamma-filamin
  • ABP-L, gamma filamin
  • filamin 2
  • 260kDa actin-binding protein
  • cgABP260 actin-binding domain
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