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FOLR2 Produits

(Folate Receptor 2 (Fetal) (FOLR2))
The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene. [provided by RefSeq, Jul 2008].

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Catégories FOLR2 en vedette

FOLR2 Anticorps

High quality antibodies with extensive validation data.

FOLR2 Kits ELISA

Reliable ELISA kits for a wide range of species.

FOLR2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

FOLR2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse
Application WB, FACS, IHC (p)
Validations
  • (1)
  • (7)
N° du produit ABIN651222
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IHC (p), IF, ICC
Validations
  • (1)
  • (2)
N° du produit ABIN2856196
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, FACS, IP, ICC
Validations
  • (2)
N° du produit ABIN2800693
Quantité 0.1 mg
Fiche technique Fiche technique

FOLR2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6955946
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN5510703
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN5526866
Quantité 96 tests
Fiche technique Fiche technique

FOLR2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
N° du produit ABIN7274664
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Cynomolgus
Source HEK-293 Cells
Validations
  • (3)
N° du produit ABIN7274663
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
N° du produit ABIN7274670
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits FOLR2

Meredith, MacNeil, Trasler, Baltz: "Growing Mouse Oocytes Transiently Activate Folate Transport via Folate Receptors As They Approach Full Size." dans: Biology of reproduction, Vol. 94, Issue 6, pp. 125, (2017) (PubMed).

Puligujja, McMillan, Kendrick, Li, Balkundi, Smith, Veerubhotla, Edagwa, Kabanov, Bronich, Gendelman, Liu: "Macrophage folate receptor-targeted antiretroviral therapy facilitates drug entry, retention, antiretroviral activities and biodistribution for reduction of human immunodeficiency virus infections." dans: Nanomedicine : nanotechnology, biology, and medicine, Vol. 9, Issue 8, pp. 1263-73, (2013) (PubMed).

Sadasivan, Cedeno, Rothenberg: "Characterization of the gene encoding a folate-binding protein expressed in human placenta. Identification of promoter activity in a G-rich SP1 site linked with the tandemly repeated GGAAG motif for the ets encoded GA-binding protein." dans: The Journal of biological chemistry, Vol. 269, Issue 7, pp. 4725-35, (1994) (PubMed).

Page, Owen, Price, Elwood: "Expression of the human placental folate receptor transcript is regulated in human tissues. Organization and full nucleotide sequence of the gene." dans: Journal of molecular biology, Vol. 229, Issue 4, pp. 1175-83, (1993) (PubMed).

Ratnam, Marquardt, Duhring, Freisheim: "Homologous membrane folate binding proteins in human placenta: cloning and sequence of a cDNA." dans: Biochemistry, Vol. 28, Issue 20, pp. 8249-54, (1990) (PubMed).

Synonymes et noms alternatifs relatifs à FOLR2

folate receptor 1 (FOLR1), folate receptor beta (FOLR2), folate receptor 2 (fetal) (FOLR2), folate receptor 2 (fetal) (Folr2), folate receptor beta (Folr2), BETA-HFR, FBP, FBP/PL-1, FBP2, Folbp-2, Folbp2, FOLR2, FR-BETA, FR-P3

Protein level used designations for FOLR2

  • folate receptor 2 (fetal)
  • folate receptor beta
  • folate receptor, beta
  • folate receptor, fetal/placental
  • folate-binding protein, fetal/placental
  • placental folate-binding protein
  • FR-beta
  • folate binding protein 2
  • folate-binding protein 2
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