FTO Produits
(Fat Mass and Obesity-Associated (FTO))
Catégories
This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. [provided by RefSeq, Jul 2011].
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Catégories FTO en vedette
FTO Anticorps
High quality antibodies with extensive validation data.
FTO Kits ELISA
Reliable ELISA kits for a wide range of species.
FTO Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
FTO recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (4)
N° du produit
ABIN7127502
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC (p), FACS
Validations
- (3)
N° du produit
ABIN390964
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, IP
Validations
- (3)
N° du produit
ABIN1169073
Quantité
100 μg
Fiche technique
Fiche technique
FTO recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6966656
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN5594574
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6228458
Quantité
96 tests
Fiche technique
Fiche technique
FTO recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1354483
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN1344345
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN1344349
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits FTO
: "m6A in mRNA coding regions promotes translation via the RNA helicase-containing YTHDC2." dans: Nature communications, Vol. 10, Issue 1, pp. 5332, (2020) (PubMed).: "Programmable RNA N6-methyladenosine editing by CRISPR-Cas9 conjugates." dans: Nature chemical biology, Vol. 15, Issue 9, pp. 865-871, (2019) (PubMed).
: "N6-Methyladenosine Guides mRNA Alternative Translation during Integrated Stress Response." dans: Molecular cell, Vol. 69, Issue 4, pp. 636-647.e7, (2019) (PubMed).
: "N6-methyladenosine RNA modification regulates embryonic neural stem cell self-renewal through histone modifications." dans: Nature neuroscience, Vol. 21, Issue 2, pp. 195-206, (2019) (PubMed).
: "Dynamic m6A modification regulates local translation of mRNA in axons." dans: Nucleic acids research, Vol. 46, Issue 3, pp. 1412-1423, (2019) (PubMed).
: "The Role of The RNA Demethylase FTO (Fat Mass and Obesity-Associated) and mRNA Methylation in Hippocampal Memory Formation." dans: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, Vol. 42, Issue 7, pp. 1502-1510, (2017) (PubMed).
: "FTO modulates circadian rhythms and inhibits the CLOCK-BMAL1-induced transcription." dans: Biochemical and biophysical research communications, Vol. 464, Issue 3, pp. 826-32, (2015) (PubMed).
: "N6-adenosine methylation in MiRNAs." dans: PLoS ONE, Vol. 10, Issue 2, pp. e0118438, (2015) (PubMed).
: "Dynamic m(6)A mRNA methylation directs translational control of heat shock response." dans: Nature, Vol. 526, Issue 7574, pp. 591-4, (2015) (PubMed).
: "The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase. ..." dans: Science (New York, N.Y.), Vol. 318, Issue 5855, pp. 1469-72, (2007) (PubMed).
Synonymes et noms alternatifs relatifs à FTO
FTO, alpha-ketoglutarate dependent dioxygenase (FTO), fat mass and obesity associated (Fto), FTO, alpha-ketoglutarate dependent dioxygenase (Fto), fat mass and obesity associated L homeolog (fto.L), AW743446, mKIAA1752, RGD1305121Protein level used designations for FTO
- alpha-ketoglutarate-dependent dioxygenase FTO
- fat mass and obesity-associated protein
- protein fto
- protein fatso
- fat mass and obesity associated protein
- Protein fatso
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