FUS Produits
(Fused in Sarcoma (FUS))
Catégories
This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6. [provided by RefSeq, Sep 2009].
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Catégories FUS en vedette
FUS Anticorps
High quality antibodies with extensive validation data.
FUS Kits ELISA
Reliable ELISA kits for a wide range of species.
FUS Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
FUS recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Cow, Dog, Human, Mouse, Pig, Rabbit, Rat
Application
WB, IHC
Validations
- (6)
N° du produit
ABIN2778717
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, ELISA, IHC, IF, FACS
Validations
- (7)
N° du produit
ABIN3031006
Quantité
0.4 mL
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, IF, IHC (p), FACS
Validations
- (4)
N° du produit
ABIN654146
Quantité
400 μL
Fiche technique
Fiche technique
FUS recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6966914
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Validations
N° du produit
ABIN1156242
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN858233
Quantité
96 tests
Fiche technique
Fiche technique
FUS recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7123020
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (5)
- (1)
N° du produit
ABIN2721461
Quantité
20 μg
Fiche technique
Fiche technique
Reactivity
Human respiratory syncytial virus B
Source
Yeast
Validations
- (1)
N° du produit
ABIN5714278
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits FUS
: "FUS (fused in sarcoma) is a component of the cellular response to topoisomerase I-induced DNA breakage and transcriptional stress." dans: Life science alliance, Vol. 2, Issue 2, (2019) (PubMed).: "PARP-1 Activation Directs FUS to DNA Damage Sites to Form PARG-Reversible Compartments Enriched in Damaged DNA." dans: Cell reports, Vol. 27, Issue 6, pp. 1809-1821.e5, (2019) (PubMed).
: "Expanded polyglutamine impairs normal nuclear distribution of fused in sarcoma and poly (rC)-binding protein 1 in Huntington's disease." dans: Neuropathology : official journal of the Japanese Society of Neuropathology, Vol. 39, Issue 5, pp. 358-367, (2019) (PubMed).
: "Heterogeneous nuclear ribonucleoproteins R and Q accumulate in pathological inclusions in FTLD-FUS." dans: Acta neuropathologica communications, Vol. 7, Issue 1, pp. 18, (2019) (PubMed).
: "Cytoplasmic Restriction of Mutated SOD1 Impairs the DNA Repair Process in Spinal Cord Neurons." dans: Cells, Vol. 8, Issue 12, (2019) (PubMed).
: "Lymphoblastoid cell lines as a model to understand amyotrophic lateral sclerosis disease mechanisms." dans: Disease models & mechanisms, Vol. 11, Issue 3, (2018) (PubMed).
: "ZFP36 RNA-binding proteins restrain T cell activation and anti-viral immunity." dans: eLife, Vol. 7, (2018) (PubMed).
: "Human proteins that interact with RNA/DNA hybrids." dans: Genome research, Vol. 28, Issue 9, pp. 1405-1414, (2018) (PubMed).
: "Molecular Dissection of FUS Points at Synergistic Effect of Low-Complexity Domains in Toxicity." dans: Cell reports, Vol. 24, Issue 3, pp. 529-537.e4, (2018) (PubMed).
: "EWS-FLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma." dans: Nature, Vol. 555, Issue 7696, pp. 387-391, (2018) (PubMed).
Synonymes et noms alternatifs relatifs à FUS
FUS RNA binding protein (FUS), fused in sarcoma (Fus), FUS RNA binding protein (Fus), fused in sarcoma (FUS), ALS6, D430004D17Rik, D930039C12Rik, ETM4, FUS/TLS, FUS1, Fus1, HNRNPP2, POMP75, TLS, TlsProtein level used designations for FUS
- 75 kDa DNA-pairing protein
- RNA-binding protein FUS
- fus-like protein
- fusion gene in myxoid liposarcoma
- heterogeneous nuclear ribonucleoprotein P2
- oncogene FUS
- oncogene TLS
- translocated in liposarcoma protein
- fusion, derived from t(12;16) malignant liposarcoma
- hnRNP P2
- pigpen protein
- protein pigpen
- translocated in liposarcoma
- fusion
- pigpen
- fusion (involved in t(12;16) in malignant liposarcoma)
- 16) in malignant liposarcoma)
- 16) malignant liposarcoma
- fusion (involved in t(12
- fusion, derived from t(12
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