FXYD1 Produits
(FXYD Domain Containing Ion Transport Regulator 1 (FXYD1))
Catégories
This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIC (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. The protein encoded by this gene is a plasma membrane substrate for several kinases, including protein kinase A, protein kinase C, NIMA kinase, and myotonic dystrophy kinase. It is thought to form an ion channel or regulate ion channel activity. Transcript variants with different 5' UTR sequences have been described in the literature. [provided by RefSeq, Jul 2008].
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Catégories FXYD1 en vedette
FXYD1 Anticorps
High quality antibodies with extensive validation data.
FXYD1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
FXYD1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC
Validations
- (3)
N° du produit
ABIN7236228
Quantité
200 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p)
Validations
- (4)
N° du produit
ABIN3043831
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Application
WB
Validations
- (1)
- (1)
N° du produit
ABIN1882173
Quantité
400 μL
Fiche technique
Fiche technique
FXYD1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
N° du produit
ABIN2728859
Quantité
20 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits FXYD1
: "Phospholemman and beta-adrenergic stimulation in the heart." dans: American journal of physiology. Heart and circulatory physiology, Vol. 298, Issue 3, pp. H807-15, (2010) (PubMed).: "FXYD1, a modulator of Na,K-ATPase activity, facilitates female sexual development by maintaining gonadotrophin-releasing hormone neuronal excitability." dans: Journal of neuroendocrinology, Vol. 21, Issue 2, pp. 108-22, (2009) (PubMed).
: "Extracellular potassium dependence of the Na+-K+-ATPase in cardiac myocytes: isoform specificity and effect of phospholemman." dans: American journal of physiology. Cell physiology, Vol. 297, Issue 3, pp. C699-705, (2009) (PubMed).
: "Left ventricular function of isoproterenol-induced hypertrophied rat hearts perfused with blood: mechanical work and energetics." dans: American journal of physiology. Heart and circulatory physiology, Vol. 297, Issue 5, pp. H1736-43, (2009) (PubMed).
Synonymes et noms alternatifs relatifs à FXYD1
FXYD domain containing ion transport regulator 1 (FXYD1), FXYD domain-containing ion transport regulator 1 (Fxyd1), 0610012C17Rik, 1110006M24Rik, PLM, Plm, PmlProtein level used designations for FXYD1
- FXYD domain containing ion transport regulator 1
- phospholemman
- FXYD domain containing ion transport regulator 1 (phospholemman)
- FXYD domain-containing ion transport regulator 1
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