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FXYD1 Produits

(FXYD Domain Containing Ion Transport Regulator 1 (FXYD1))

Catégories

This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIC (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. The protein encoded by this gene is a plasma membrane substrate for several kinases, including protein kinase A, protein kinase C, NIMA kinase, and myotonic dystrophy kinase. It is thought to form an ion channel or regulate ion channel activity. Transcript variants with different 5' UTR sequences have been described in the literature. [provided by RefSeq, Jul 2008].

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Catégories FXYD1 en vedette

FXYD1 Anticorps

High quality antibodies with extensive validation data.

FXYD1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

FXYD1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (3)
N° du produit ABIN7236228
Quantité 200 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IHC (p)
Validations
  • (4)
N° du produit ABIN3043831
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse
Application WB
Validations
  • (1)
  • (1)
N° du produit ABIN1882173
Quantité 400 μL
Fiche technique Fiche technique

FXYD1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
N° du produit ABIN2728859
Quantité 20 μg
Fiche technique Fiche technique

Dernières publications sur nos produits FXYD1

Wang, Gao, Song, Zhang, Li, Koch, Tucker, Philipson, Chan, Feldman, Cheung: "Phospholemman and beta-adrenergic stimulation in the heart." dans: American journal of physiology. Heart and circulatory physiology, Vol. 298, Issue 3, pp. H807-15, (2010) (PubMed).

Garcia-Rudaz, Deng, Matagne, Ronnekleiv, Bosch, Han, Percy, Ojeda: "FXYD1, a modulator of Na,K-ATPase activity, facilitates female sexual development by maintaining gonadotrophin-releasing hormone neuronal excitability." dans: Journal of neuroendocrinology, Vol. 21, Issue 2, pp. 108-22, (2009) (PubMed).

Han, Tucker, Lingrel, Despa, Bers: "Extracellular potassium dependence of the Na+-K+-ATPase in cardiac myocytes: isoform specificity and effect of phospholemman." dans: American journal of physiology. Cell physiology, Vol. 297, Issue 3, pp. C699-705, (2009) (PubMed).

Nakajima-Takenaka, Zhang, Obata, Tohne, Matsuyoshi, Nagai, Nishiyama, Takaki: "Left ventricular function of isoproterenol-induced hypertrophied rat hearts perfused with blood: mechanical work and energetics." dans: American journal of physiology. Heart and circulatory physiology, Vol. 297, Issue 5, pp. H1736-43, (2009) (PubMed).

Synonymes et noms alternatifs relatifs à FXYD1

FXYD domain containing ion transport regulator 1 (FXYD1), FXYD domain-containing ion transport regulator 1 (Fxyd1), 0610012C17Rik, 1110006M24Rik, PLM, Plm, Pml

Protein level used designations for FXYD1

  • FXYD domain containing ion transport regulator 1
  • phospholemman
  • FXYD domain containing ion transport regulator 1 (phospholemman)
  • FXYD domain-containing ion transport regulator 1
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