FZD1 Produits
(Frizzled Family Receptor 1 (Fzd1))
Catégories
Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK- 3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. Activated by Wnt3A, Wnt3, Wnt1 and to a lesser extent Wnt2, but not by Wnt4, Wnt5A, Wnt5B, Wnt6, Wnt7A or Wnt7B.
antibodies-online.com est synonyme de produits de recherche de haute qualité. Cherchez, trouvez et commandez des outils avec des données de validation étendues, des images, des références. Notre service clientèle scientifique est toujours à votre disposition si vous avez des questions sur la sélection ou l'application de nos produits.
Catégories FZD1 en vedette
FZD1 Anticorps
High quality antibodies with extensive validation data.
FZD1 Kits ELISA
Reliable ELISA kits for a wide range of species.
FZD1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
FZD1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (8)
N° du produit
ABIN7435805
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (4)
N° du produit
ABIN7153179
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (3)
N° du produit
ABIN7153175
Quantité
100 μg
Fiche technique
Fiche technique
FZD1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6966904
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6955998
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6730674
Quantité
96 tests
Fiche technique
Fiche technique
FZD1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Source
Human Cells
Validations
- (1)
N° du produit
ABIN7320532
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (1)
N° du produit
ABIN7195855
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Human Cells
Validations
N° du produit
ABIN4371866
Quantité
50 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits FZD1
: "Overexpression of FZD1 and CAIX are Associated with Invasion, Metastasis, and Poor-Prognosis of the Pancreatic Ductal Adenocarcinoma." dans: Pathology oncology research : POR, Vol. 24, Issue 4, pp. 899-906, (2018) (PubMed).: "Transcriptional Regulation of Frizzled-1 in Human Osteoblasts by Sp1." dans: PLoS ONE, Vol. 11, Issue 10, pp. e0163277, (2017) (PubMed).
: "β-Catenin-dependent pathway activation by both promiscuous "canonical" WNT3a-, and specific "noncanonical" WNT4- and WNT5a-FZD receptor combinations with strong differences in LRP5 and LRP6 ..." dans: Cellular signalling, Vol. 26, Issue 2, pp. 260-7, (2013) (PubMed).
: "Functional and association analysis of frizzled 1 (FZD1) promoter haplotypes with femoral neck geometry." dans: Bone, Vol. 46, Issue 4, pp. 1131-7, (2010) (PubMed).
: "Secreted Frizzled-related protein-1 is a negative regulator of androgen receptor activity in prostate cancer." dans: British journal of cancer, Vol. 100, Issue 7, pp. 1165-74, (2009) (PubMed).
: "A cryptic frizzled module in cell surface collagen 18 inhibits Wnt/beta-catenin signaling." dans: PLoS ONE, Vol. 3, Issue 4, pp. e1878, (2008) (PubMed).
: "Genomic profile of matrix and vasculature remodeling in TGF-alpha induced pulmonary fibrosis." dans: American journal of respiratory cell and molecular biology, Vol. 37, Issue 3, pp. 309-21, (2007) (PubMed).
: "R-Spondin1 regulates Wnt signaling by inhibiting internalization of LRP6." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 37, pp. 14700-5, (2007) (PubMed).
: "Cross-talk between Wnt signaling pathways in human mesenchymal stem cells leads to functional antagonism during osteogenic differentiation." dans: Journal of cellular biochemistry, Vol. 101, Issue 5, pp. 1109-24, (2007) (PubMed).
: "Bone morphogenetic protein-2 modulates Wnt and frizzled expression and enhances the canonical pathway of Wnt signaling in normal keratinocytes." dans: Journal of dermatological science, Vol. 42, Issue 2, pp. 111-9, (2006) (PubMed).
Synonymes et noms alternatifs relatifs à FZD1
frizzled (fz), frizzled class receptor 1 (FZD1), frizzled class receptor 1 (Fzd1), frizzled class receptor 1 L homeolog (fzd1.L), AW227548, cFz-1, CG3646, CG17697, DFz, DFZ1, DFz1, Dfz1, Dmel\\CG17697, Dm Fz1, frizzled1, Frz, frz, frz-1, frz1, FZ, Fz, Fz-1, FZ-1, Fz1, fz1, fzd1-A, fz[[1]], Xfrizzled-1Protein level used designations for FZD1
- CG17697-PA
- CG17697-PB
- CG17697-PC
- Frizzled1
- frazzled
- frizzled 1
- frizzled[[1]]
- fz-PA
- fz-PB
- fz-PC
- frizzled 1, seven transmembrane spanning receptor
- frizzled homolog 1
- Wnt receptor
- frizzled, Drosophila, homolog of, 1
- frizzled-1
- fz-1
- fzE1
- hFz1
- 7-transmembrane protein frizzled-1
- Drosophila polarity gene (frizzled) homologue
- Drosophila polarity gene homolog 1
- rFz1
- 7-transmembrane receptor frizzled-1
- xfz1
- mFz1
Vous êtes ici:
