FZD6 Produits
(Frizzled Family Receptor 6 (FZD6))
Catégories
This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants, some of which do not encode a protein with a predicted signal peptide.[provided by RefSeq, Aug 2011].
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Catégories FZD6 en vedette
FZD6 Anticorps
High quality antibodies with extensive validation data.
FZD6 Kits ELISA
Reliable ELISA kits for a wide range of species.
FZD6 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
FZD6 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Monkey
Application
IHC, ICC, IHC (p)
Validations
- (3)
N° du produit
ABIN1048614
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, ELISA, IHC, IF, ICC
Validations
- (3)
N° du produit
ABIN6258792
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Mouse, Rat
Application
WB, ELISA, ICC, IHC (p), IHC (fro), IF (cc), IF (p)
Validations
- (2)
N° du produit
ABIN1713791
Quantité
100 μL
Fiche technique
Fiche technique
FZD6 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6955999
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN2533595
Quantité
96 tests
Fiche technique
Fiche technique
FZD6 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1354586
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7398062
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
N° du produit
ABIN7317167
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits FZD6
: "Functional dissection of the N-terminal extracellular domains of Frizzled 6 reveals their roles for receptor localization and Dishevelled recruitment." dans: The Journal of biological chemistry, Vol. 293, Issue 46, pp. 17875-17887, (2018) (PubMed).: "A role for core planar polarity proteins in cell contact-mediated orientation of planar cell division across the mammalian embryonic skin." dans: Scientific reports, Vol. 7, Issue 1, pp. 1880, (2017) (PubMed).
: "Transcriptomic analysis comparing mouse strains with extreme total lung capacities identifies novel candidate genes for pulmonary function." dans: Respiratory research, Vol. 18, Issue 1, pp. 152, (2017) (PubMed).
: "Cell and Tissue Scale Forces Coregulate Fgfr2-Dependent Tetrads and Rosettes in the Mouse Embryo." dans: Biophysical journal, Vol. 112, Issue 10, pp. 2209-2218, (2017) (PubMed).
: "The spatio-temporal domains of Frizzled6 action in planar polarity control of hair follicle orientation." dans: Developmental biology, Vol. 409, Issue 1, pp. 181-93, (2015) (PubMed).
: "Anisotropic stress orients remodelling of mammalian limb bud ectoderm." dans: Nature cell biology, Vol. 17, Issue 5, pp. 569-79, (2015) (PubMed).
: "Otitis media in sperm-associated antigen 6 (Spag6)-deficient mice." dans: PLoS ONE, Vol. 9, Issue 11, pp. e112879, (2014) (PubMed).
: "Restoration of WNT4 inhibits cell growth in leukemia-derived cell lines." dans: BMC cancer, Vol. 13, pp. 557, (2013) (PubMed).
: "Regulation of PCDH15 function in mechanosensory hair cells by alternative splicing of the cytoplasmic domain." dans: Development (Cambridge, England), Vol. 138, Issue 8, pp. 1607-17, (2011) (PubMed).
: "Secreted Frizzled-related protein-1 is a negative regulator of androgen receptor activity in prostate cancer." dans: British journal of cancer, Vol. 100, Issue 7, pp. 1165-74, (2009) (PubMed).
Synonymes et noms alternatifs relatifs à FZD6
frizzled class receptor 6 (fzd6), frizzled class receptor 6 S homeolog (fzd6.S), frizzled class receptor 6 (FZD6), frizzled class receptor 6 (Fzd6), frizzled-6, Frizzled-6, frizzled6, frz6, FZ-6, fz6, FZ6, Fz6, HFZ6, NDNC10, Xfrz6, zgc:65879, zgc:77440Protein level used designations for FZD6
- frizzled-6
- frizzled homolog 6
- frizzled 6
- frizzled 6, seven transmembrane spanning receptor
- seven transmembrane helix receptor
- fz-6
- involved in Wnt signaling, encoding a Wnt receptor
- mFz6
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- G Antigen 1
- G Antigen 12B
- G Antigen 12F
- G Antigen 12G
- G Antigen 12H
- G Antigen 12I
- G Antigen 13
- G Antigen 2A
- G Antigen 2C
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