GAB2 Produits
(GRB2-Associated Binding Protein 2 (GAB2))
Catégories
This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Nov 2009].
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Catégories GAB2 en vedette
GAB2 Anticorps
High quality antibodies with extensive validation data.
GAB2 Kits ELISA
Reliable ELISA kits for a wide range of species.
GAB2 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
GAB2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (4)
N° du produit
ABIN7154436
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (4)
N° du produit
ABIN685273
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Rat
Application
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (4)
N° du produit
ABIN685288
Quantité
100 μL
Fiche technique
Fiche technique
GAB2 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN1380840
Quantité
2 x 96 tests
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN1380841
Quantité
2 x 96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6217340
Quantité
96 tests
Fiche technique
Fiche technique
GAB2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1354623
Quantité
25 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7416967
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3092725
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits GAB2
: "K48-Linked Ubiquitination Contributes to Nicotine-Augmented Bone Marrow-Derived Dendritic-Cell-Mediated Adaptive Immunity." dans: Vaccines, Vol. 9, Issue 3, (2021) (PubMed).: "PYR-41 and Thalidomide Impair Dendritic Cell Cross-Presentation by Inhibiting Myddosome Formation and Attenuating the Endosomal Recruitments of p97 and Sec61 via NF-κB Inactivation." dans: Journal of immunology research, Vol. 2018, pp. 5070573, (2018) (PubMed).
: "Decreased expression of Gab2 in patients with temporal lobe epilepsy and pilocarpine-induced rat model." dans: Synapse (New York, N.Y.), Vol. 68, Issue 4, pp. 168-77, (2014) (PubMed).
: "In vivo multiplexed interrogation of amplified genes identifies GAB2 as an ovarian cancer oncogene." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 3, pp. 1102-7, (2014) (PubMed).
: "Gab2-mediated signaling promotes melanoma metastasis." dans: The American journal of pathology, Vol. 174, Issue 4, pp. 1524-33, (2009) (PubMed).
: "A role for the scaffolding adapter GAB2 in breast cancer." dans: Nature medicine, Vol. 12, Issue 1, pp. 114-21, (2006) (PubMed).
: "From gene expression analysis to tissue microarrays: a rational approach to identify therapeutic and diagnostic targets in lymphoid malignancies." dans: Molecular & cellular proteomics : MCP, Vol. 5, Issue 6, pp. 1072-81, (2006) (PubMed).
: "Docking protein Gab2 is phosphorylated by ZAP-70 and negatively regulates T cell receptor signaling by recruitment of inhibitory molecules." dans: The Journal of biological chemistry, Vol. 276, Issue 48, pp. 45175-83, (2001) (PubMed).
Synonymes et noms alternatifs relatifs à GAB2
GRB2 associated binding protein 2 (GAB2), GRB2 associated binding protein 2 (gab2), GRB2-associated binding protein 2 (Gab2), growth factor receptor bound protein 2-associated protein 2 (Gab2), AI463667, D130058I17Rik, GAB2, p97Protein level used designations for GAB2
- GRB2-associated binding protein 2
- GRB2-associated-binding protein 2
- Grb2-associated binder 2
- growth factor receptor bound protein 2-associated protein 2
- pp100
- GRB2-associated binder 2
- Grb2 associated binder 2
- PH domain-containing adaptor molecule p97
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