GABRA1 Produits
(gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1))
Catégories
This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008].
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Catégories GABRA1 en vedette
GABRA1 Anticorps
High quality antibodies with extensive validation data.
GABRA1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
GABRA1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Rat
Application
WB, IHC, ICC, IF
Validations
- (4)
N° du produit
ABIN2485717
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Rat
Application
WB, ICC, IF, AA
Validations
- (4)
N° du produit
ABIN863138
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Rat
Application
WB, IHC, ICC, IF
Validations
- (4)
N° du produit
ABIN2485730
Quantité
100 μg
Fiche technique
Fiche technique
GABRA1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6228560
Quantité
96 tests
Fiche technique
Fiche technique
GABRA1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
N° du produit
ABIN1354645
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7123050
Quantité
50 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits GABRA1
: "Corticotropin-Releasing Factor Receptor-1 Neurons in the Lateral Amygdala Display Selective Sensitivity to Acute and Chronic Ethanol Exposure." dans: eNeuro, Vol. 7, Issue 2, (2020) (PubMed).: "Strain-specific programming of prenatal ethanol exposure across generations." dans: Alcohol (Fayetteville, N.Y.), Vol. 60, pp. 191-199, (2017) (PubMed).
: "α2 Subunit-Containing GABAA Receptor Subtypes Are Upregulated and Contribute to Alcohol-Induced Functional Plasticity in the Rat Hippocampus." dans: Molecular pharmacology, Vol. 92, Issue 2, pp. 101-112, (2017) (PubMed).
: "How to Make an Active Zone: Unexpected Universal Functional Redundancy between RIMs and RIM-BPs." dans: Neuron, Vol. 91, Issue 4, pp. 792-807, (2016) (PubMed).
: "Grp94 Protein Delivers γ-Aminobutyric Acid Type A (GABAA) Receptors to Hrd1 Protein-mediated Endoplasmic Reticulum-associated Degradation." dans: The Journal of biological chemistry, Vol. 291, Issue 18, pp. 9526-39, (2016) (PubMed).
: "Role of microRNA-4458 in patients with non-small-cell lung cancer." dans: Oncology letters, Vol. 12, Issue 5, pp. 3958-3966, (2016) (PubMed).
: "The human epilepsy mutation GABRG2(Q390X) causes chronic subunit accumulation and neurodegeneration." dans: Nature neuroscience, Vol. 18, Issue 7, pp. 988-96, (2015) (PubMed).
: "The developmental evolution of the seizure phenotype and cortical inhibition in mouse models of juvenile myoclonic epilepsy." dans: Neurobiology of disease, Vol. 82, pp. 164-175, (2015) (PubMed).
: "GABAergic interneuronal loss and reduced inhibitory synaptic transmission in the hippocampal CA1 region after mild traumatic brain injury." dans: Experimental neurology, Vol. 273, pp. 11-23, (2015) (PubMed).
: "Seizure-related regulation of GABAA receptors in spontaneously epileptic rats." dans: Neurobiology of disease, Vol. 77, pp. 246-56, (2015) (PubMed).
Synonymes et noms alternatifs relatifs à GABRA1
gamma-aminobutyric acid type A receptor alpha1 subunit (GABRA1), gamma-aminobutyric acid type A receptor alpha1 subunit (Gabra1), gamma-aminobutyric acid (GABA) A receptor, alpha 1 (gabra1), gamma-aminobutyric acid (GABA) A receptor, alpha 1 (GABRA1), gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1 (Gabra1), gamma-aminobutyric acid receptor subunit alpha-1 (LOC100653509), ECA4, EJM, EJM5, Gabra-1, zgc:153566Protein level used designations for GABRA1
- GABA(A) receptor subunit alpha-1
- GABA(A) receptor, alpha 1
- gamma-aminobutyric acid receptor subunit alpha-1
- gamma-aminobutyric acid A receptor, alpha 1
- gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 1
- gamma-aminobutyric acid A receptor, alpha 1
- gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
- GABAA alpha 1
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