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GABRA1 Produits

(gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1))

Catégories

This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008].

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Catégories GABRA1 en vedette

GABRA1 Anticorps

High quality antibodies with extensive validation data.

GABRA1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

GABRA1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Application WB, IHC, ICC, IF
Validations
  • (4)
N° du produit ABIN2485717
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Rat
Application WB, ICC, IF, AA
Validations
  • (4)
N° du produit ABIN863138
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Rat
Application WB, IHC, ICC, IF
Validations
  • (4)
N° du produit ABIN2485730
Quantité 100 μg
Fiche technique Fiche technique

GABRA1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6228560
Quantité 96 tests
Fiche technique Fiche technique

GABRA1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
N° du produit ABIN1354645
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7123050
Quantité 50 μg
Fiche technique Fiche technique

Dernières publications sur nos produits GABRA1

Agoglia, Zhu, Ying, Sidhu, Natividad, Wolfe, Buczynski, Contet, Parsons, Roberto, Herman: "Corticotropin-Releasing Factor Receptor-1 Neurons in the Lateral Amygdala Display Selective Sensitivity to Acute and Chronic Ethanol Exposure." dans: eNeuro, Vol. 7, Issue 2, (2020) (PubMed).

Popoola, Nizhnikov, Cameron: "Strain-specific programming of prenatal ethanol exposure across generations." dans: Alcohol (Fayetteville, N.Y.), Vol. 60, pp. 191-199, (2017) (PubMed).

Lindemeyer, Shen, Yazdani, Shao, Spigelman, Davies, Olsen, Liang: "α2 Subunit-Containing GABAA Receptor Subtypes Are Upregulated and Contribute to Alcohol-Induced Functional Plasticity in the Rat Hippocampus." dans: Molecular pharmacology, Vol. 92, Issue 2, pp. 101-112, (2017) (PubMed).

Acuna, Liu, Südhof: "How to Make an Active Zone: Unexpected Universal Functional Redundancy between RIMs and RIM-BPs." dans: Neuron, Vol. 91, Issue 4, pp. 792-807, (2016) (PubMed).

Di, Wang, Han, Fu, Duerfeldt, Blagg, Mu: "Grp94 Protein Delivers γ-Aminobutyric Acid Type A (GABAA) Receptors to Hrd1 Protein-mediated Endoplasmic Reticulum-associated Degradation." dans: The Journal of biological chemistry, Vol. 291, Issue 18, pp. 9526-39, (2016) (PubMed).

Bao, Wang, Wei, Wang, Wuyun, Bo: "Role of microRNA-4458 in patients with non-small-cell lung cancer." dans: Oncology letters, Vol. 12, Issue 5, pp. 3958-3966, (2016) (PubMed).

Kang, Shen, Zhou, Xu, Macdonald: "The human epilepsy mutation GABRG2(Q390X) causes chronic subunit accumulation and neurodegeneration." dans: Nature neuroscience, Vol. 18, Issue 7, pp. 988-96, (2015) (PubMed).

Arain, Zhou, Ding, Zaidi, Gallagher: "The developmental evolution of the seizure phenotype and cortical inhibition in mouse models of juvenile myoclonic epilepsy." dans: Neurobiology of disease, Vol. 82, pp. 164-175, (2015) (PubMed).

Almeida-Suhett, Prager, Pidoplichko, Figueiredo, Marini, Li, Eiden, Braga: "GABAergic interneuronal loss and reduced inhibitory synaptic transmission in the hippocampal CA1 region after mild traumatic brain injury." dans: Experimental neurology, Vol. 273, pp. 11-23, (2015) (PubMed).

González, Grabenstatter, Cea-Del Rio, Cruz Del Angel, Carlsen, Laoprasert, White, Huntsman, Brooks-Kayal: "Seizure-related regulation of GABAA receptors in spontaneously epileptic rats." dans: Neurobiology of disease, Vol. 77, pp. 246-56, (2015) (PubMed).

Synonymes et noms alternatifs relatifs à GABRA1

gamma-aminobutyric acid type A receptor alpha1 subunit (GABRA1), gamma-aminobutyric acid type A receptor alpha1 subunit (Gabra1), gamma-aminobutyric acid (GABA) A receptor, alpha 1 (gabra1), gamma-aminobutyric acid (GABA) A receptor, alpha 1 (GABRA1), gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1 (Gabra1), gamma-aminobutyric acid receptor subunit alpha-1 (LOC100653509), ECA4, EJM, EJM5, Gabra-1, zgc:153566

Protein level used designations for GABRA1

  • GABA(A) receptor subunit alpha-1
  • GABA(A) receptor, alpha 1
  • gamma-aminobutyric acid receptor subunit alpha-1
  • gamma-aminobutyric acid A receptor, alpha 1
  • gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 1
  • gamma-aminobutyric acid A receptor, alpha 1
  • gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
  • GABAA alpha 1
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