GABRA4 Produits
(gamma-aminobutyric Acid (GABA) A Receptor, alpha 4 (GABRA4))
Catégories
Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. This gene encodes subunit alpha-4, which is involved in the etiology of autism and eventually increases autism risk through interaction with another subunit, gamma-aminobutyric acid receptor beta-1 (GABRB1). Alternatively spliced transcript variants encoding different isoforms have been found in this gene.[provided by RefSeq, Feb 2011].
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Catégories GABRA4 en vedette
GABRA4 Anticorps
High quality antibodies with extensive validation data.
GABRA4 Kits ELISA
Reliable ELISA kits for a wide range of species.
GABRA4 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
GABRA4 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (4)
N° du produit
ABIN7153483
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC
Validations
- (3)
N° du produit
ABIN3181674
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA
Validations
- (3)
N° du produit
ABIN2565552
Quantité
100 μg
Fiche technique
Fiche technique
GABRA4 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6228561
Quantité
96 tests
Fiche technique
Fiche technique
GABRA4 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN2565117
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1354651
Quantité
25 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7423147
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits GABRA4
: "Early growth response 1 (Egr-1) directly regulates GABAA receptor α2, α4, and θ subunits in the hippocampus." dans: Journal of neurochemistry, Vol. 133, Issue 4, pp. 489-500, (2015) (PubMed).: "Downregulation of Gabra4 expression during alcohol withdrawal is mediated by specific microRNAs in cultured mouse cortical neurons." dans: Brain and behavior, Vol. 5, Issue 8, pp. e00355, (2015) (PubMed).
: "Altered intrathalamic GABAA neurotransmission in a mouse model of a human genetic absence epilepsy syndrome." dans: Neurobiology of disease, Vol. 73C, pp. 407-417, (2014) (PubMed).
: "Chronic ethanol and withdrawal differentially modulate lateral/basolateral amygdala paracapsular and local GABAergic synapses." dans: The Journal of pharmacology and experimental therapeutics, Vol. 337, Issue 1, pp. 162-70, (2011) (PubMed).
: "Distinct mechanisms regulate GABAA receptor and gephyrin clustering at perisomatic and axo-axonic synapses on CA1 pyramidal cells." dans: The Journal of physiology, Vol. 589, Issue Pt 20, pp. 4959-80, (2011) (PubMed).
: "Mice lacking Gad2 show altered behavioral effects of ethanol, flurazepam and gabaxadol." dans: Addiction biology, Vol. 15, Issue 1, pp. 45-61, (2009) (PubMed).
: "Developmental maturation of synaptic and extrasynaptic GABAA receptors in mouse thalamic ventrobasal neurones." dans: The Journal of physiology, Vol. 586, Issue 4, pp. 965-87, (2008) (PubMed).
: "Alcohol regulates gene expression in neurons via activation of heat shock factor 1." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 27, Issue 47, pp. 12957-66, (2007) (PubMed).
: "Effect of chronic administration of ethanol on the regulation of tyrosine kinase phosphorylation of the GABAA receptor subunits in the rat brain." dans: Neurochemical research, Vol. 32, Issue 7, pp. 1179-87, (2007) (PubMed).
: "Egr3 stimulation of GABRA4 promoter activity as a mechanism for seizure-induced up-regulation of GABA(A) receptor alpha4 subunit expression." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 33, pp. 11894-9, (2005) (PubMed).
Synonymes et noms alternatifs relatifs à GABRA4
gamma-aminobutyric acid type A receptor alpha4 subunit (GABRA4), gamma-aminobutyric acid type A receptor alpha4 subunit (Gabra4), gamma-aminobutyric acid (GABA) A receptor, subunit alpha 4 (Gabra4), Gabra-4, GABRA4Protein level used designations for GABRA4
- gamma-aminobutyric acid (GABA) A receptor, alpha 4
- gamma-aminobutyric acid A receptor, alpha 4
- GABA(A) receptor subunit alpha-4
- gamma-aminobutyric acid receptor subunit alpha-4-like
- GABA-A receptor alpha-4 subunit
- gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 4
- gamma-aminobutyric acid receptor subunit alpha-4
- GABA(A) receptor, alpha 4
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