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GABRB1 Produits

(gamma-aminobutyric Acid (GABA) A Receptor, Subunit beta 1 (GABRB1))

Catégories

The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 1 subunit. It is mapped to chromosome 4p12 in a cluster comprised of genes encoding alpha 4, alpha 2 and gamma 1 subunits of the GABA A receptor. Alteration of this gene is implicated in the pathogenetics of schizophrenia. [provided by RefSeq, Jul 2008].

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Catégories GABRB1 en vedette

GABRB1 Anticorps

High quality antibodies with extensive validation data.

GABRB1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

GABRB1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA
Validations
  • (3)
N° du produit ABIN7241390
Quantité 200 μL
Fiche technique Fiche technique
Reactivity Mouse, Rat
Application WB, IHC, ICC
Validations
  • (1)
  • (3)
N° du produit ABIN1742466
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IHC (p)
Validations
  • (2)
N° du produit ABIN604919
Quantité 50 μL
Fiche technique Fiche technique

GABRB1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6229781
Quantité 96 tests
Fiche technique Fiche technique

GABRB1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1354658
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits GABRB1

Hernandez, Kong, Hu, Zhang, Shen, Jackson, Liu, Jiang, Macdonald: "Altered Channel Conductance States and Gating of GABAA Receptors by a Pore Mutation Linked to Dravet Syndrome." dans: eNeuro, Vol. 4, Issue 1, (2017) (PubMed).

Kerti-Szigeti, Nusser: "Similar GABAA receptor subunit composition in somatic and axon initial segment synapses of hippocampal pyramidal cells." dans: eLife, Vol. 5, (2016) (PubMed).

King, Manning, Trimmer: "A unique ion channel clustering domain on the axon initial segment of mammalian neurons." dans: The Journal of comparative neurology, Vol. 522, Issue 11, pp. 2594-608, (2014) (PubMed).

Ohkawa, Satake, Yokoi, Miyazaki, Ohshita, Sobue, Takashima, Watanabe, Fukata, Fukata: "Identification and characterization of GABA(A) receptor autoantibodies in autoimmune encephalitis." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, Issue 24, pp. 8151-63, (2014) (PubMed).

Zhou, Huang, Ding, Deel, Arain, Murray, Patel, Flanagan, Gallagher: "Altered cortical GABAA receptor composition, physiology, and endocytosis in a mouse model of a human genetic absence epilepsy syndrome." dans: The Journal of biological chemistry, Vol. 288, Issue 29, pp. 21458-72, (2013) (PubMed).

Eyre, Renzi, Farrant, Nusser: "Setting the time course of inhibitory synaptic currents by mixing multiple GABA(A) receptor ? subunit isoforms." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 17, pp. 5853-67, (2012) (PubMed).

Gutierrez, Mark, Masseck, Maejima, Kuckelsberg, Hyde, Krause, Kruse, Herlitze: "Optogenetic control of motor coordination by Gi/o protein-coupled vertebrate rhodopsin in cerebellar Purkinje cells." dans: The Journal of biological chemistry, Vol. 286, Issue 29, pp. 25848-58, (2011) (PubMed).

Pöltl, Hauer, Fuchs, Tretter, Sieghart: "Subunit composition and quantitative importance of GABA(A) receptor subtypes in the cerebellum of mouse and rat." dans: Journal of neurochemistry, Vol. 87, Issue 6, pp. 1444-55, (2004) (PubMed).

Ogris, Pöltl, Hauer, Ernst, Oberto, Wulff, Höger, Wisden, Sieghart: "Affinity of various benzodiazepine site ligands in mice with a point mutation in the GABA(A) receptor gamma2 subunit." dans: Biochemical pharmacology, Vol. 68, Issue 8, pp. 1621-9, (2004) (PubMed).

McKernan, Rosahl, Reynolds, Sur, Wafford, Atack, Farrar, Myers, Cook, Ferris, Garrett, Bristow, Marshall, Macaulay, Brown, Howell, Moore, Carling, Street, Castro, Ragan, Dawson, Whiting: "Sedative but not anxiolytic properties of benzodiazepines are mediated by the GABA(A) receptor alpha1 subtype." dans: Nature neuroscience, Vol. 3, Issue 6, pp. 587-92, (2000) (PubMed).

Synonymes et noms alternatifs relatifs à GABRB1

gamma-aminobutyric acid type A receptor beta1 subunit (GABRB1), gamma-aminobutyric acid (GABA) A receptor, subunit beta 1 (Gabrb1), gamma-aminobutyric acid type A receptor beta 1 subunit (Gabrb1), gamma-aminobutyric acid (GABA) A receptor, beta 1 (gabrb1), gamma-aminobutyric acid type A receptor beta1 subunit (Gabrb1), AW061132, B230208N19Rik, Gabrb-1, GARB1, si:dkey-20i10.4

Protein level used designations for GABRB1

  • GABA(A) receptor subunit beta-1
  • GABA(A) receptor, beta 1
  • gamma-aminobutyric acid receptor subunit beta-1
  • Gamma-aminobutyric acid receptor beta 1
  • gamma-aminobutyric acid (GABA) A receptor, beta 1
  • gamma-aminobutyric acid (GABA-A) receptor, subunit beta 1
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