GAD65 Produits
(Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2))
Catégories
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008].
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Catégories GAD65 en vedette
GAD65 Anticorps
High quality antibodies with extensive validation data.
GAD65 Kits ELISA
Reliable ELISA kits for a wide range of species.
GAD65 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
GAD65 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (6)
N° du produit
ABIN7433339
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IP
Validations
- (6)
N° du produit
ABIN949999
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (5)
N° du produit
ABIN7437707
Quantité
100 μL
Fiche technique
Fiche technique
GAD65 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6967053
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6967052
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6956137
Quantité
96 tests
Fiche technique
Fiche technique
GAD65 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (2)
- (1)
N° du produit
ABIN1354671
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Baculovirus infected Insect Cells
Validations
- (1)
N° du produit
ABIN7320200
Quantité
20 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Baculovirus infected Insect Cells
Validations
- (1)
N° du produit
ABIN7320201
Quantité
50 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits GAD65
: "Regulation of morphine-induced synaptic alterations: Role of oxidative stress, ER stress, and autophagy." dans: The Journal of cell biology, Vol. 215, Issue 2, pp. 245-258, (2016) (PubMed).: "Early GABAergic transmission defects in the external globus pallidus and rest/activity rhythm alteration in a mouse model of Huntington's disease." dans: Neuroscience, Vol. 329, pp. 363-79, (2016) (PubMed).
: "Feedback modulation of neural network synchrony and seizure susceptibility by Mdm2-p53-Nedd4-2 signaling." dans: Molecular brain, Vol. 9, pp. 32, (2016) (PubMed).
: "Antibodies to inhibitory synaptic proteins in neurological syndromes associated with glutamic acid decarboxylase autoimmunity." dans: PLoS ONE, Vol. 10, Issue 3, pp. e0121364, (2015) (PubMed).
: "Neuron-astrocyte interaction enhance GABAergic synaptic transmission in a manner dependent on key metabolic enzymes." dans: Frontiers in cellular neuroscience, Vol. 9, pp. 120, (2015) (PubMed).
: "Vesicular glutamate transporter 1 orchestrates recruitment of other synaptic vesicle cargo proteins during synaptic vesicle recycling." dans: The Journal of biological chemistry, Vol. 290, Issue 37, pp. 22593-601, (2015) (PubMed).
: "Acrylamide neurotoxicity on the cerebrum of weaning rats." dans: Neural regeneration research, Vol. 10, Issue 6, pp. 938-43, (2015) (PubMed).
: "The active zone protein family ELKS supports Ca2+ influx at nerve terminals of inhibitory hippocampal neurons." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, Issue 37, pp. 12289-303, (2014) (PubMed).
: "Immunocytochemical identification of electroneutral Na⁺-coupled HCO₃⁻ transporters in freshly dissociated mouse medullary raphé neurons." dans: Neuroscience, Vol. 246, pp. 451-67, (2013) (PubMed).
: "Prenatal stress affects network properties of rat hippocampal neurons." dans: Biological psychiatry, Vol. 73, Issue 11, pp. 1095-102, (2013) (PubMed).
Synonymes et noms alternatifs relatifs à GAD65
glutamate decarboxylase 2 (GAD2), glutamate decarboxylase 2 (PTRG_06148), glutamate decarboxylase 2 (LOC9324534), glutamate decarboxylase 2 (Gad2), glutamate decarboxylase 1 (GAD1), glutamate decarboxylase 2 (gad2), glutamic acid decarboxylase 2 (Gad2), 6330404F12Rik, F12P19.12, F12P19_12, GAD(65), Gad-2, GAD65, gad65, GLUTAMATE DECARBOXYLASE 2, glutamate decarboxylase 2, zgc:112198Protein level used designations for GAD65
- glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
- glutamate decarboxylase 2
- glutamic acid decarboxylase
- 65 kDa glutamic acid decarboxylase
- GAD-65
- Glutamate decarboxylase 2 (islet)
- glutamate decarboxylase 65 kDa isoform
- glutamic acid decarboxylase 2
- glutamic acid decarboxylase 65
- Glutamate decarboxylase-2 (pancreas)
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