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GAD65 Produits

(Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2))

Catégories

This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008].

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Catégories GAD65 en vedette

GAD65 Anticorps

High quality antibodies with extensive validation data.

GAD65 Kits ELISA

Reliable ELISA kits for a wide range of species.

GAD65 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

GAD65 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (6)
N° du produit ABIN7433339
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IP
Validations
  • (6)
N° du produit ABIN949999
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (5)
N° du produit ABIN7437707
Quantité 100 μL
Fiche technique Fiche technique

GAD65 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6967053
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6967052
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6956137
Quantité 96 tests
Fiche technique Fiche technique

GAD65 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (2)
  • (1)
N° du produit ABIN1354671
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Baculovirus infected Insect Cells
Validations
  • (1)
N° du produit ABIN7320200
Quantité 20 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Baculovirus infected Insect Cells
Validations
  • (1)
N° du produit ABIN7320201
Quantité 50 μg
Fiche technique Fiche technique

Dernières publications sur nos produits GAD65

Cai, Yang, Hu, Chen, Niu, Yuan, Liu, Xiong, Arikkath, Buch: "Regulation of morphine-induced synaptic alterations: Role of oxidative stress, ER stress, and autophagy." dans: The Journal of cell biology, Vol. 215, Issue 2, pp. 245-258, (2016) (PubMed).

Du, Chazalon, Bestaven, Leste-Lasserre, Baufreton, Cazalets, Cho, Garret: "Early GABAergic transmission defects in the external globus pallidus and rest/activity rhythm alteration in a mouse model of Huntington's disease." dans: Neuroscience, Vol. 329, pp. 363-79, (2016) (PubMed).

Jewett, Christian, Bacos, Lee, Zhu, Tsai: "Feedback modulation of neural network synchrony and seizure susceptibility by Mdm2-p53-Nedd4-2 signaling." dans: Molecular brain, Vol. 9, pp. 32, (2016) (PubMed).

Gresa-Arribas, Ariño, Martínez-Hernández, Petit-Pedrol, Sabater, Saiz, Dalmau, Graus: "Antibodies to inhibitory synaptic proteins in neurological syndromes associated with glutamic acid decarboxylase autoimmunity." dans: PLoS ONE, Vol. 10, Issue 3, pp. e0121364, (2015) (PubMed).

Kaczor, Rakus, Mozrzymas: "Neuron-astrocyte interaction enhance GABAergic synaptic transmission in a manner dependent on key metabolic enzymes." dans: Frontiers in cellular neuroscience, Vol. 9, pp. 120, (2015) (PubMed).

Pan, Marrs, Ryan: "Vesicular glutamate transporter 1 orchestrates recruitment of other synaptic vesicle cargo proteins during synaptic vesicle recycling." dans: The Journal of biological chemistry, Vol. 290, Issue 37, pp. 22593-601, (2015) (PubMed).

Tian, Ma, Shi, Lou, Liu, Li: "Acrylamide neurotoxicity on the cerebrum of weaning rats." dans: Neural regeneration research, Vol. 10, Issue 6, pp. 938-43, (2015) (PubMed).

Liu, Bickford, Held, Nyitrai, Südhof, Kaeser: "The active zone protein family ELKS supports Ca2+ influx at nerve terminals of inhibitory hippocampal neurons." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, Issue 37, pp. 12289-303, (2014) (PubMed).

Coley, Ruffin, Moss, Hopfer, Boron: "Immunocytochemical identification of electroneutral Na⁺-coupled HCO₃⁻ transporters in freshly dissociated mouse medullary raphé neurons." dans: Neuroscience, Vol. 246, pp. 451-67, (2013) (PubMed).

Grigoryan, Segal: "Prenatal stress affects network properties of rat hippocampal neurons." dans: Biological psychiatry, Vol. 73, Issue 11, pp. 1095-102, (2013) (PubMed).

Synonymes et noms alternatifs relatifs à GAD65

glutamate decarboxylase 2 (GAD2), glutamate decarboxylase 2 (PTRG_06148), glutamate decarboxylase 2 (LOC9324534), glutamate decarboxylase 2 (Gad2), glutamate decarboxylase 1 (GAD1), glutamate decarboxylase 2 (gad2), glutamic acid decarboxylase 2 (Gad2), 6330404F12Rik, F12P19.12, F12P19_12, GAD(65), Gad-2, GAD65, gad65, GLUTAMATE DECARBOXYLASE 2, glutamate decarboxylase 2, zgc:112198

Protein level used designations for GAD65

  • glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
  • glutamate decarboxylase 2
  • glutamic acid decarboxylase
  • 65 kDa glutamic acid decarboxylase
  • GAD-65
  • Glutamate decarboxylase 2 (islet)
  • glutamate decarboxylase 65 kDa isoform
  • glutamic acid decarboxylase 2
  • glutamic acid decarboxylase 65
  • Glutamate decarboxylase-2 (pancreas)
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