GADD45A Produits
(Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))
Catégories
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.[provided by RefSeq, Dec 2010].
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Catégories GADD45A en vedette
GADD45A Anticorps
High quality antibodies with extensive validation data.
GADD45A Kits ELISA
Reliable ELISA kits for a wide range of species.
GADD45A Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
GADD45A recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IF
Validations
- (6)
N° du produit
ABIN6140923
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, FACS, ICC, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (1)
- (3)
N° du produit
ABIN685432
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, FACS
Validations
- (1)
- (3)
N° du produit
ABIN650724
Quantité
400 μL
Fiche technique
Fiche technique
GADD45A recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6975062
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6956310
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6956311
Quantité
96 tests
Fiche technique
Fiche technique
GADD45A recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1354677
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1354675
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7505208
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits GADD45A
: "The Natural Compound Neobractatin Induces Cell Cycle Arrest by Regulating E2F1 and Gadd45α." dans: Frontiers in oncology, Vol. 9, pp. 654, (2019) (PubMed).: "Significance of S100P as a biomarker in diagnosis, prognosis and therapy of opisthorchiasis-associated cholangiocarcinoma." dans: International journal of cancer. Journal international du cancer, (2015) (PubMed).
: "CArG-driven GADD45α activated by resveratrol inhibits lung cancer cells." dans: Genes & cancer, Vol. 6, Issue 5-6, pp. 220-30, (2015) (PubMed).
: "Docetaxel-loaded solid lipid nanoparticles suppress breast cancer cells growth with reduced myelosuppression toxicity." dans: International journal of nanomedicine, Vol. 9, pp. 4829-46, (2014) (PubMed).
: "p53 controls hepatitis C virus non-structural protein 5A-mediated downregulation of GADD45α expression via the NF-κB and PI3K-Akt pathways." dans: The Journal of general virology, Vol. 94, Issue Pt 2, pp. 326-35, (2013) (PubMed).
: "Inhibition of NF-?B activation sensitizes U937 cells to 3'-azido-3'-deoxythymidine induced apoptosis." dans: Cell death & disease, Vol. 1, pp. e81, (2011) (PubMed).
: "Methylation-mediated repression of GADD45alpha in prostate cancer and its role as a potential therapeutic target." dans: Cancer research, Vol. 69, Issue 4, pp. 1527-35, (2009) (PubMed).
: "Decitabine-induced demethylation of 5' CpG island in GADD45A leads to apoptosis in osteosarcoma cells." dans: Neoplasia (New York, N.Y.), Vol. 10, Issue 5, pp. 471-80, (2008) (PubMed).
Synonymes et noms alternatifs relatifs à GADD45A
growth arrest and DNA damage inducible alpha L homeolog (gadd45a.L), growth arrest and DNA-damage-inducible, alpha, b (gadd45ab), growth arrest and DNA damage inducible alpha (GADD45A), growth arrest and DNA damage inducible alpha (gadd45a), growth arrest and DNA damage-inducible protein 45 (GADD45), growth arrest and DNA-damage-inducible 45 alpha (Gadd45a), growth arrest and DNA-damage-inducible, alpha (Gadd45a), AA545191, ddit1, Ddit1, DDIT1, gadd45, GADD45, Gadd45, gadd45a, GADD45A, MGC53491, zgc:91795Protein level used designations for GADD45A
- growth arrest and DNA-damage-inducible, alpha
- growth arrest and DNA damage-inducible protein GADD45 alpha
- growth arrest and DNA-damage-inducible protein 45 alpha
- growth arrest and DNA-damage-inducible protein alpha
- growth arrest and DNA damage-inducible protein 45
- Growth arrest and DNA-damage-inducible protein GADD45 alpha
- DDIT-1
- DNA damage-inducible transcript 1 protein
- DNA-damage inducible transcript 1
- DNA-damage-inducible transcript 1
- Gadd45alpha
- growth arrest and DNA-damage-inducible protein GADD45 alpha
- DNA damage-inducible transcript-1
- growth arrest and DNA-damage-inducible 45 alpha
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