G6PC Produits
(Glucose 6-Phosphatase, Catalytic (G6PC))
Catégories
Glucose-6-phosphatase (G6Pase) is a multi-subunit integral membrane protein of the endoplasmic reticulum that is composed of a catalytic subunit and transporters for G6P, inorganic phosphate, and glucose. This gene (G6PC) is one of the three glucose-6-phosphatase catalytic-subunit-encoding genes in human: G6PC, G6PC2 and G6PC3. Glucose-6-phosphatase catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate and is a key enzyme in glucose homeostasis, functioning in gluconeogenesis and glycogenolysis. Mutations in this gene cause glycogen storage disease type I (GSD1). This disease, also known as von Gierke disease, is a metabolic disorder characterized by severe hypoglycemia associated with the accumulation of glycogen and fat in the liver and kidneys.[provided by RefSeq, Feb 2011].
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Catégories G6PC en vedette
G6PC Anticorps
High quality antibodies with extensive validation data.
G6PC Kits ELISA
Reliable ELISA kits for a wide range of species.
G6PC Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
G6PC recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC
Validations
- (1)
- (6)
N° du produit
ABIN2781770
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, FACS, IHC (p)
Validations
- (4)
N° du produit
ABIN651417
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application
WB
Validations
- (3)
- (3)
N° du produit
ABIN2781769
Quantité
100 μL
Fiche technique
Fiche technique
G6PC recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6956119
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6956120
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6956121
Quantité
96 tests
Fiche technique
Fiche technique
G6PC recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1354607
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7409233
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7399592
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits G6PC
: "Berberine inhibits gluconeogenesis in spontaneous diabetic rats by regulating the AKT/MAPK/NO/cGMP/PKG signaling pathway." dans: Molecular and cellular biochemistry, (2023) (PubMed).: "Trimethylamine N-Oxide Binds and Activates PERK to Promote Metabolic Dysfunction." dans: Cell metabolism, Vol. 30, Issue 6, pp. 1141-1151.e5, (2019) (PubMed).
: "Targeting CASP8 and FADD-like apoptosis regulator ameliorates nonalcoholic steatohepatitis in mice and nonhuman primates." dans: Nature medicine, Vol. 23, Issue 4, pp. 439-449, (2017) (PubMed).
: "Hepatocyte TRAF3 promotes liver steatosis and systemic insulin resistance through targeting TAK1-dependent signalling." dans: Nature communications, Vol. 7, pp. 10592, (2016) (PubMed).
: "Niclosamide ethanolamine-induced mild mitochondrial uncoupling improves diabetic symptoms in mice." dans: Nature medicine, Vol. 20, Issue 11, pp. 1263-9, (2014) (PubMed).
: "Uric acid-dependent inhibition of AMP kinase induces hepatic glucose production in diabetes and starvation: evolutionary implications of the uricase loss in hominids." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 28, Issue 8, pp. 3339-50, (2014) (PubMed).
: "Role of Fas-associated death domain-containing protein (FADD) phosphorylation in regulating glucose homeostasis: from proteomic discovery to physiological validation." dans: Molecular & cellular proteomics : MCP, Vol. 12, Issue 10, pp. 2689-700, (2013) (PubMed).
: "Branched-chain amino acid supplementation reduces oxidative stress and prolongs survival in rats with advanced liver cirrhosis." dans: PLoS ONE, Vol. 8, Issue 7, pp. e70309, (2013) (PubMed).
Synonymes et noms alternatifs relatifs à G6PC
glucose-6-phosphatase, catalytic (G6pc), glucose-6-phosphatase catalytic subunit (G6PC), glucose-6-phosphatase, catalytic subunit (G6pc), AW107337, G-6-Pase, G6Pase, G6PC1, G6pt, G6PT, Glc-6-Pase, GSD1, GSD1aProtein level used designations for G6PC
- G-6-Pase
- Glc-6-Pase-alpha
- glucose-6-phosphatase
- G6Pase
- G6Pase-alpha
- glucose-6-phosphatase alpha
- glucose-6-phosphatase, catalytic (glycogen storage disease type I, von Gierke disease)
- glucose-6-phosphatase catalytic subunit
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- G Protein-Coupled Receptor Kinase 7
- G Protein-Coupled Receptor 89B
- G Protein-Coupled Receptor 89
- G Protein-Coupled Receptor 34
- G Protein-Coupled Receptor 31
- G Protein-Coupled Receptor 182
- G Protein-Coupled Receptor 133
- G Protein-Coupled Receptor 132
- G Protein-Coupled Receptor 128
- G Protein-Coupled Receptor 126
- G Protein-Coupled Receptor 12
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