GEM Produits
(GTP Binding Protein Overexpressed in Skeletal Muscle (GEM))
Catégories
This gene encodes a protein that plays a critical role in cell cycle regulation. The encoded protein inhibits DNA replication by binding to DNA replication factor Cdt1, preventing the incorporation of minichromosome maintenance proteins into the pre-replication complex. The encoded protein is expressed during the S and G2 phases of the cell cycle and is degraded by the anaphase-promoting complex during the metaphase-anaphase transition. Increased expression of this gene may play a role in several malignancies including colon, rectal and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and two pseudogenes of this gene are located on the short arm of chromosome 16. [provided by RefSeq, Oct 2011].
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Catégories GEM en vedette
GEM Anticorps
High quality antibodies with extensive validation data.
GEM Kits ELISA
Reliable ELISA kits for a wide range of species.
GEM Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
GEM recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Bat, Cow, Dog, Guinea Pig, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat, Xenopus laevis
Application
WB, IHC, IHC (p)
Validations
- (3)
N° du produit
ABIN203412
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Dog, Human, Mouse, Rat
Application
WB, IHC
Validations
- (3)
N° du produit
ABIN630220
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application
WB, IHC
Validations
- (4)
N° du produit
ABIN2775304
Quantité
100 μL
Fiche technique
Fiche technique
GEM recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Validations
N° du produit
ABIN1135704
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Validations
N° du produit
ABIN1135705
Quantité
96 tests
Fiche technique
Fiche technique
GEM recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Cell-free protein synthesis (CFPS)
Validations
N° du produit
ABIN3080640
Quantité
250 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Cell-free protein synthesis (CFPS)
Validations
N° du produit
ABIN3120438
Quantité
250 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
N° du produit
ABIN2721788
Quantité
20 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits GEM
: "Nerve injury induces a Gem-GTPase-dependent downregulation of P/Q-type Ca2+ channels contributing to neurite plasticity in dorsal root ganglion neurons." dans: Pflügers Archiv : European journal of physiology, Vol. 467, Issue 2, pp. 351-66, (2015) (PubMed).: "High expression of GEM and EDNRA is associated with metastasis and poor outcome in patients with advanced bladder cancer." dans: BMC cancer, Vol. 14, pp. 638, (2014) (PubMed).
: "A systemic network for Chlamydia pneumoniae entry into human cells." dans: Journal of bacteriology, Vol. 192, Issue 11, pp. 2809-15, (2010) (PubMed).
: "Equine herpesvirus 1 enters cells by two different pathways, and infection requires the activation of the cellular kinase ROCK1." dans: Journal of virology, Vol. 81, Issue 20, pp. 10879-89, (2007) (PubMed).
Synonymes et noms alternatifs relatifs à GEM
GTP binding protein overexpressed in skeletal muscle (GEM), GTP binding protein overexpressed in skeletal muscle (gem), GTP binding protein overexpressed in skeletal muscle (Gem), geminin, DNA replication inhibitor (GMNN), GTP binding protein (gene overexpressed in skeletal muscle) (Gem), AV020497, DKFZp470D0612, GEM, Gem, KIR, kir, LOC100221129, xgem, zgc:153003Protein level used designations for GEM
- GTP-binding mitogen-induced T-cell protein
- GTP-binding protein GEM
- GTP-binding protein overexpressed in skeletal muscle
- RAS-like protein KIR
- kinase-inducible Ras-like protein
- GTP binding protein overexpressed in skeletal muscle
- Gem GTPase
- GTP binding protein gene overexpressed in skeletal muscle
- GTP binding protein (gene overexpressed in skeletal muscle)
- geminin
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