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GFRA1 Produits

(GDNF Family Receptor alpha 1 (GFRA1))
Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Feb 2009].

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Catégories GFRA1 en vedette

GFRA1 Anticorps

High quality antibodies with extensive validation data.

GFRA1 Kits ELISA

Reliable ELISA kits for a wide range of species.

GFRA1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

GFRA1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (6)
N° du produit ABIN7430060
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IF
Validations
  • (1)
  • (5)
N° du produit ABIN6141065
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
N° du produit ABIN7153717
Quantité 100 μg
Fiche technique Fiche technique

GFRA1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6966987
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6966986
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Pig
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6966988
Quantité 96 tests
Fiche technique Fiche technique

GFRA1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
N° du produit ABIN7274741
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1355034
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1778939
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits GFRA1

Li, Ao, Wu: "Systematic identification and comparison of expressed profiles of lncRNAs and circRNAs with associated co-expression and ceRNA networks in mouse germline stem cells." dans: Oncotarget, Vol. 8, Issue 16, pp. 26573-26590, (2018) (PubMed).

Ma, Zhou, Li, Zheng, Wu, Niu, Tang, He, Li, Hua: "Lin28a promotes self-renewal and proliferation of dairy goat spermatogonial stem cells (SSCs) through regulation of mTOR and PI3K/AKT." dans: Scientific reports, Vol. 6, pp. 38805, (2016) (PubMed).

Li, Bhave, Chow, Riera, Schlee, Rauch, Atanasova, Cate, Whitty: "Quantitative analysis of receptor tyrosine kinase-effector coupling at functionally relevant stimulus levels." dans: The Journal of biological chemistry, Vol. 290, Issue 16, pp. 10018-36, (2015) (PubMed).

Lippoldt, Elmes, McCoy, Knowlton, McKemy: "Artemin, a glial cell line-derived neurotrophic factor family member, induces TRPM8-dependent cold pain." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 30, pp. 12543-52, (2013) (PubMed).

Barrenschee, Böttner, Hellwig, Harde, Egberts, Becker, Wedel: "Site-specific gene expression and localization of growth factor ligand receptors RET, GFRα1 and GFRα2 in human adult colon." dans: Cell and tissue research, Vol. 354, Issue 2, pp. 371-80, (2013) (PubMed).

Lozada, Karlstedt, Panula, Aarnisalo: "Unilateral labyrinthectomy induced changes on GDNF receptor complex proteins in the rat medial vestibular nuclei." dans: Journal of vestibular research : equilibrium & orientation, Vol. 16, Issue 4-5, pp. 171-7, (2007) (PubMed).

He, Jiang, Hofmann, Dym: "Gfra1 silencing in mouse spermatogonial stem cells results in their differentiation via the inactivation of RET tyrosine kinase." dans: Biology of reproduction, Vol. 77, Issue 4, pp. 723-33, (2007) (PubMed).

Weis, Marksteiner, Humpel: "Nerve growth factor and glial cell line-derived neurotrophic factor restore the cholinergic neuronal phenotype in organotypic brain slices of the basal nucleus of Meynert." dans: Neuroscience, Vol. 102, Issue 1, pp. 129-38, (2001) (PubMed).

Wiesenhofer, Stockhammer, Kostron, Maier, Hinterhuber, Humpel: "Glial cell line-derived neurotrophic factor (GDNF) and its receptor (GFR-alpha 1) are strongly expressed in human gliomas." dans: Acta neuropathologica, Vol. 99, Issue 2, pp. 131-7, (2000) (PubMed).

Cohen: "Caspases: the executioners of apoptosis." dans: The Biochemical journal, Vol. 326 ( Pt 1), Issue 5693, pp. 1-16, (1997) (PubMed).

Synonymes et noms alternatifs relatifs à GFRA1

GDNF family receptor alpha 1 (gfra1), GDNF family receptor alpha 1 (GFRA1), glial cell line derived neurotrophic factor family receptor alpha 1 (Gfra1), GDNF family receptor alpha 1 (Gfra1), gdnf family receptor alpha 1a (gfra1a), AU042498, gdnfr, GDNFR, gdnfra, GDNFRA, GDNFRALPHA, gfr-alpha-1, GFR-ALPHA-1, GFRA1, gfralpha1a, MGC122616, ret1l, RET1L, retl1, RETL1, trnr1, TRNR1, zgc:110129

Protein level used designations for GFRA1

  • GDNF family receptor alpha 1
  • GDNF family receptor alpha-1
  • GDNF receptor alpha-1
  • GDNFR-alpha-1
  • GPI-linked anchor protein
  • Glial cell line-derived neurotrophic factor receptor alpha
  • PI-linked cell-surface accessory protein
  • RET ligand 1
  • TGF-beta related neurotrophic factor receptor 1
  • TGF-beta-related neurotrophic factor receptor 1
  • GDNF receptor alpha
  • GFR-alpha-1
  • GDNF family receptor alpha-1-like
  • GDNFR-alpha
  • GFR alpha-1
  • glial cell line derived neurotrophic factor family receptor alpha 1
  • gdnf family receptor alpha 1a
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