This gene is a member of a gene family that encodes enzymes involved in both the metabolism of glutathione and in the transpeptidation of amino acids. Changes in the activity of gamma-glutamyltransferase may signal preneoplastic or toxic conditions in the liver or kidney. The protein encoded by this gene consists of a heavy and a light chain, and it can interact with CT120, a plasma membrane-associated protein that is possibly involved in lung carcinogenesis. [provided by RefSeq, Jul 2008].
antibodies-online.com est synonyme de produits de recherche de haute qualité. Cherchez, trouvez et commandez des outils avec des données de validation étendues, des images, des références. Notre service clientèle scientifique est toujours à votre disposition si vous avez des questions sur la sélection ou l'application de nos produits.
Grimm, Hofstetter, Aust, Mutz-Dehbalaie, Bruch, Heinze, Rahhal-Schupp, Reinthaller, Concin, Polterauer: "Association of gamma-glutamyltransferase with severity of disease at diagnosis and prognosis of ovarian cancer." dans: British journal of cancer, Vol. 109, Issue 3, pp. 610-4, (2013) (PubMed).