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GIPR Produits

(Gastric Inhibitory Polypeptide Receptor (GIPR))
This gene encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes. [provided by RefSeq, Oct 2011].

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Catégories GIPR en vedette

GIPR Anticorps

High quality antibodies with extensive validation data.

GIPR Kits ELISA

Reliable ELISA kits for a wide range of species.

GIPR Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

GIPR recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (4)
N° du produit ABIN7153669
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC (p), FACS
Validations
  • (1)
  • (3)
N° du produit ABIN391714
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (3)
N° du produit ABIN6258423
Quantité 100 μL
Fiche technique Fiche technique

GIPR recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN5594084
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN5594085
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method
Validations
N° du produit ABIN1134494
Quantité 96 tests
Fiche technique Fiche technique

GIPR recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
N° du produit ABIN7491651
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Mammalian Cells
Validations
  • (1)
N° du produit ABIN7538299
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
N° du produit ABIN7491455
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits GIPR

Ussher, Campbell, Mulvihill, Baggio, Bates, McLean, Gopal, Capozzi, Yusta, Cao, Ali, Kim, Kabir, Seino, Suzuki, Drucker: "Inactivation of the Glucose-Dependent Insulinotropic Polypeptide Receptor Improves Outcomes following Experimental Myocardial Infarction." dans: Cell metabolism, Vol. 27, Issue 2, pp. 450-460.e6, (2018) (PubMed).

Campbell, Ussher, Mulvihill, Kolic, Baggio, Cao, Liu, Lamont, Morii, Streutker, Tamarina, Philipson, Wrana, MacDonald, Drucker: "TCF1 links GIPR signaling to the control of beta cell function and survival." dans: Nature medicine, Vol. 22, Issue 1, pp. 84-90, (2016) (PubMed).

Snook, Nelson, Dyck, Wright, Holloway: "Glucose-dependent insulinotropic polypeptide directly induces glucose transport in rat skeletal muscle." dans: American journal of physiology. Regulatory, integrative and comparative physiology, Vol. 309, Issue 3, pp. R295-303, (2015) (PubMed).

Sparre-Ulrich, Hansen, Svendsen, Christensen, Knop, Hartmann, Holst, Rosenkilde: "Species-specific action of (Pro3)GIP - a full agonist at human GIP receptors, but a partial agonist and competitive antagonist at rat and mouse GIP receptors." dans: British journal of pharmacology, Vol. 173, Issue 1, pp. 27-38, (2015) (PubMed).

Ugleholdt, Pedersen, Bassi, Füchtbauer, Jørgensen, Kissow, Nytofte, Poulsen, Rosenkilde, Seino, Thams, Holst, Holst: "Transgenic rescue of adipocyte glucose-dependent insulinotropic polypeptide receptor expression restores high fat diet-induced body weight gain." dans: The Journal of biological chemistry, Vol. 286, Issue 52, pp. 44632-45, (2011) (PubMed).

Figueiredo, Antunes, Moreira, de Mello, Medeiros, Di Giunta, Lobão-Soares, Linhares, Lin, Mazzuco, Prediger, Walz: "Glucose-dependent insulinotropic peptide receptor expression in the hippocampus and neocortex of mesial temporal lobe epilepsy patients and rats undergoing pilocarpine induced status epilepticus." dans: Peptides, Vol. 32, Issue 4, pp. 781-9, (2011) (PubMed).

Prasadan, Koizumi, Tulachan, Shiota, Lath, Paredes, Guo, El-Gohary, Malek, Shah, Gittes: "The expression and function of glucose-dependent insulinotropic polypeptide in the embryonic mouse pancreas." dans: Diabetes, Vol. 60, Issue 2, pp. 548-54, (2011) (PubMed).

Kim, Nian, McIntosh: "Adipocyte expression of the glucose-dependent insulinotropic polypeptide receptor involves gene regulation by PPARγ and histone acetylation." dans: Journal of lipid research, Vol. 52, Issue 4, pp. 759-70, (2011) (PubMed).

Gao, Coope, Grant, Ma, Ley, Harhaj: "ABIN1 protein cooperates with TAX1BP1 and A20 proteins to inhibit antiviral signaling." dans: The Journal of biological chemistry, Vol. 286, Issue 42, pp. 36592-602, (2011) (PubMed).

Synonymes et noms alternatifs relatifs à GIPR

gastric inhibitory polypeptide receptor (GIPR), glucagon receptor (LOC100303705), gastric inhibitory polypeptide receptor (Gipr), GIP-R, Gippr, GIPR, Gm160, Gm1081, PGQTL2, RATGIPPR

Protein level used designations for GIPR

  • gastric inhibitory polypeptide receptor
  • glucagon receptor
  • gastric inhibitory polypeptide receptor-like
  • GIP-R
  • glucose-dependent insulinotropic polypeptide receptor
  • gastric inhibitory peptide receptor
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