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GIT1 Produits

(GIT1)
GTPase-activating protein for the ADP ribosylation factor family. May serve as a scaffold to bring together molecules to form signaling modules controlling vesicle trafficking, adhesion and cytoskeletal organization. Increases the speed of cell migration, as well as the size and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodia. Sequesters inactive non-tyrosine- phosphorylated paxillin in cytoplasmic complexes (By similarity).

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Catégories GIT1 en vedette

GIT1 Anticorps

High quality antibodies with extensive validation data.

GIT1 Kits ELISA

Reliable ELISA kits for a wide range of species.

GIT1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

GIT1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IF
Validations
  • (5)
N° du produit ABIN7267383
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (4)
N° du produit ABIN7144546
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, FACS
Validations
  • (4)
N° du produit ABIN6242999
Quantité 400 μL
Fiche technique Fiche technique

GIT1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method
Validations
N° du produit ABIN1122359
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method
Validations
N° du produit ABIN1122360
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method
Validations
N° du produit ABIN1122361
Quantité 96 tests
Fiche technique Fiche technique

GIT1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3092784
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3135633
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
N° du produit ABIN2721889
Quantité 20 μg
Fiche technique Fiche technique

Dernières publications sur nos produits GIT1

Li, Tang, Zhou, Wang, Xu, Zhao, Huang, Kong, Liu, Cheng, Zhou, Zhao, Gu, Luo, Tao, Qian, Chen, Fan, Yin: "GIT1 regulates angiogenic factor secretion in bone marrow mesenchymal stem cells via NF-κB/Notch signalling to promote angiogenesis." dans: Cell proliferation, Vol. 52, Issue 6, pp. e12689, (2019) (PubMed).

Zhao, Kong, Cai, Xu, Zhou, Wang, Xu, Yang, Chen, Tang, Wang, Cheng, Luo, Zhou, Li, Huang, Zhao, Yin, Xue, Fan: "GIT1 contributes to autophagy in osteoclast through disruption of the binding of Beclin1 and Bcl2 under starvation condition." dans: Cell death & disease, Vol. 9, Issue 12, pp. 1195, (2018) (PubMed).

Chen, Wang, Zhou, Zhou, Tang, Xu, Liu, Li, Cheng, Zhou, Fan, Yin: "GPCR kinase 2-interacting protein-1 protects against ischemia-reperfusion injury of the spinal cord by modulating ASK1/JNK/p38 signaling." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, pp. fj201800548, (2018) (PubMed).

Brimer, Wade, Vande Pol: "Interactions between E6, FAK, and GIT1 at paxillin LD4 are necessary for transformation by bovine papillomavirus 1 E6." dans: Journal of virology, Vol. 88, Issue 17, pp. 9927-33, (2014) (PubMed).

Boczonadi, Gillespie, Keenan, Ramsbottom, Donald-Wilson, Al Nazer, Humbert, Schwarz, Chaudhry, Henderson: "Scrib:Rac1 interactions are required for the morphogenesis of the ventricular myocardium." dans: Cardiovascular research, Vol. 104, Issue 1, pp. 103-15, (2014) (PubMed).

Aslan, Baker, Loren, Haley, Itakura, Pang, Greenberg, David, Manser, Chernoff, McCarty: "The PAK system links Rho GTPase signaling to thrombin-mediated platelet activation." dans: American journal of physiology. Cell physiology, Vol. 305, Issue 5, pp. C519-28, (2013) (PubMed).

Won, Mah, Kim, Kim, Hahm, Kim, Cho, Kim, Jang, Cho, Kim, Shin, Seo, Jeong, Choi, Kim, Kang, Kim: "GIT1 is associated with ADHD in humans and ADHD-like behaviors in mice." dans: Nature medicine, Vol. 17, Issue 5, pp. 566-72, (2011) (PubMed).

Wade, Brimer, Lyons, Vande Pol: "Paxillin enables attachment-independent tyrosine phosphorylation of focal adhesion kinase and transformation by RAS." dans: The Journal of biological chemistry, Vol. 286, Issue 44, pp. 37932-44, (2011) (PubMed).

Moreau, Piguel, Papouin, Koehl, Durand, Rubio, Loll, Richard, Mazzocco, Racca, Oliet, Abrous, Montcouquiol, Sans: "The planar polarity protein Scribble1 is essential for neuronal plasticity and brain function." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 29, pp. 9738-52, (2010) (PubMed).

Klemmer, Smit, Li: "Proteomics analysis of immuno-precipitated synaptic protein complexes." dans: Journal of proteomics, Vol. 72, Issue 1, pp. 82-90, (2009) (PubMed).

Synonymes et noms alternatifs relatifs à GIT1

GIT ArfGAP 1 (GIT1), GIT ArfGAP 1 (Git1), G protein-coupled receptor kinase interacting ArfGAP 1 (GIT1), G protein-coupled receptor kinase-interactor 1 (Git1), Cat-1, p95Cat

Protein level used designations for GIT1

  • ARF GAP GIT1
  • ARF GTPase-activating protein GIT1
  • CAT-1
  • CAT1
  • G protein-coupled receptor kinase interactor 1
  • G protein-coupled receptor kinase-interactor 1
  • GRK-interacting protein 1
  • cool-associated and tyrosine-phosphorylated protein 1
  • G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein (GIT1)
  • G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein
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