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GLS2 Produits

(Glutaminase 2 (Liver, Mitochondrial) (GLS2))

Catégories

The protein encoded by this gene is a mitochondrial phosphate-activated glutaminase that catalyzes the hydrolysis of glutamine to stoichiometric amounts of glutamate and ammonia. This protein is functionally similar to the kidney glutaminase but is a little smaller in size. Originally thought to be liver-specific, this protein has been found in other tissues as well. At least one transcribed pseudogene has been found for this gene. [provided by RefSeq, Jul 2008].

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Catégories GLS2 en vedette

GLS2 Anticorps

High quality antibodies with extensive validation data.

GLS2 Kits ELISA

Reliable ELISA kits for a wide range of species.

GLS2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

GLS2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Application WB, IHC, ICC, IP
Validations
  • (6)
N° du produit ABIN7436594
Quantité 100 μL
Fiche technique Fiche technique

Application WB, IHC
Validations
  • (2)
  • (4)
N° du produit ABIN2781319
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (1)
  • (2)
N° du produit ABIN652216
Quantité 400 μL
Fiche technique Fiche technique

GLS2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6956184
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method
Validations
N° du produit ABIN1134923
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method
Validations
N° du produit ABIN1134924
Quantité 96 tests
Fiche technique Fiche technique

GLS2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1355246
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7399565
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN2722007
Quantité 50 μg
Fiche technique Fiche technique

Dernières publications sur nos produits GLS2

Wang, Liu, Yao, Li, Yang, Zhang, Chen, Wang: "18F-labeled magnetic nanoparticles for monitoring anti-angiogenic therapeutic effects in breast cancer xenografts." dans: Journal of nanobiotechnology, Vol. 17, Issue 1, pp. 105, (2019) (PubMed).

Shroff, Eberlin, Dang, Gouw, Gabay, Adam, Bellovin, Tran, Philbrick, Garcia-Ocana, Casey, Li, Dang, Zare, Felsher: "MYC oncogene overexpression drives renal cell carcinoma in a mouse model through glutamine metabolism." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 21, pp. 6539-44, (2015) (PubMed).

Gross, Demo, Dennison, Chen, Chernov-Rogan, Goyal, Janes, Laidig, Lewis, Li, Mackinnon, Parlati, Rodriguez, Shwonek, Sjogren, Stanton, Wang, Yang, Zhao, Bennett: "Antitumor activity of the glutaminase inhibitor CB-839 in triple-negative breast cancer." dans: Molecular cancer therapeutics, Vol. 13, Issue 4, pp. 890-901, (2014) (PubMed).

Hu, Lausted, Yoo, Yan, Brightman, Chen, Wang, Bu, Hood: "Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity." dans: Theranostics, Vol. 4, Issue 2, pp. 215-28, (2014) (PubMed).

Shimmura, Suzuki, Iwata, Tsuchiya, Ohno, Matsuzaki, Iwata, Kameno, Takahashi, Wakuda, Nakamura, Hashimoto, Mori: "Enzymes in the glutamate-glutamine cycle in the anterior cingulate cortex in postmortem brain of subjects with autism." dans: Molecular autism, Vol. 4, Issue 1, pp. 6, (2013) (PubMed).

Toriumi, Mouri, Narusawa, Aoyama, Ikawa, Lu, Nagai, Mamiya, Kim, Nabeshima: "Prenatal NMDA receptor antagonism impaired proliferation of neuronal progenitor, leading to fewer glutamatergic neurons in the prefrontal cortex." dans: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, Vol. 37, Issue 6, pp. 1387-96, (2012) (PubMed).

Zacharias, McCullough, Shanmugavelandy, Lee, Lee, Dutta, McHenry, Nguyen, Norton, Jones, Bhattacharya: "Metabolic Differences in Glutamine Utilization Lead to Metabolic Vulnerabilities in Prostate Cancer." dans: Scientific reports, Vol. 7, Issue 1, pp. 16159 (PubMed).

Synonymes et noms alternatifs relatifs à GLS2

glutaminase 2 (glsA2), glutaminase 2 (LOAG_03311), glutaminase 2a (liver, mitochondrial) (gls2a), glutaminase 2 (GLS2), glutaminase 2 (liver, mitochondrial) (Gls2), glutaminase 2 (Gls2), A330074B06Rik, AI195532, GA, Ga, GLS, hLGA, LGA, Lga, si:ch211-216k22.10

Protein level used designations for GLS2

  • glutaminase 2
  • L-glutamine amidohydrolase
  • breast cell glutaminase
  • glutaminase I
  • glutaminase liver isoform, mitochondrial
  • phosphate-activated glutaminase
  • phosphate-dependent glutaminase
  • L-glutaminase
  • liver mitochondrial glutaminase
  • GLS
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