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GNAQ Produits

(Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ))

Catégories

This locus encodes a guanine nucleotide-binding protein. The encoded protein, an alpha subunit in the Gq class, couples a seven-transmembrane domain receptor to activation of phospolipase C-beta. Mutations at this locus have been associated with problems in platelet activation and aggregation. A related pseudogene exists on chromosome 2.[provided by RefSeq, Nov 2010].

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Catégories GNAQ en vedette

GNAQ Anticorps

High quality antibodies with extensive validation data.

GNAQ Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

GNAQ recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IHC (p)
Validations
  • (1)
  • (6)
N° du produit ABIN2855848
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (1)
  • (5)
N° du produit ABIN516106
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (4)
N° du produit ABIN763181
Quantité 100 μL
Fiche technique Fiche technique

GNAQ recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7123242
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1355347
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1355345
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits GNAQ

Rushton, Korb, Kummer, Reichart, Fuchs-Baumgartinger, Tichy, Nell: "Protein expression of KIT, BRAF, GNA11, GNAQ and RASSF1 in feline diffuse iris melanomas." dans: Veterinary journal (London, England : 1997), Vol. 249, pp. 33-40, (2019) (PubMed).

Sánchez-Fernández, Cabezudo, Caballero, García-Hoz, Tall, Klett, Michnick, Mayor, Ribas: "Protein Kinase C ζ Interacts with a Novel Binding Region of Gαq to Act as a Functional Effector." dans: The Journal of biological chemistry, Vol. 291, Issue 18, pp. 9513-25, (2016) (PubMed).

Ngai, Inngjerdingen, Berge, Taskén: "Interplay between the heterotrimeric G-protein subunits Galphaq and Galphai2 sets the threshold for chemotaxis and TCR activation." dans: BMC immunology, Vol. 10, pp. 27, (2009) (PubMed).

Dutt, Kjoller, Giel, Hall, Toksoz: "Activated Galphaq family members induce Rho GTPase activation and Rho-dependent actin filament assembly." dans: FEBS letters, Vol. 531, Issue 3, pp. 565-9, (2002) (PubMed).

Li, Iyengar: "Calpain as an effector of the Gq signaling pathway for inhibition of Wnt/beta -catenin-regulated cell proliferation." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 20, pp. 13254-9, (2002) (PubMed).

Strathmann, Simon: "G protein diversity: a distinct class of alpha subunits is present in vertebrates and invertebrates." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, Issue 23, pp. 9113-7, (1991) (PubMed).

Synonymes et noms alternatifs relatifs à GNAQ

guanine nucleotide binding protein (G protein), q polypeptide (gnaq), G protein subunit alpha q (GNAQ), G protein subunit alpha q (Gnaq), guanine nucleotide binding protein (G protein), q polypeptide S homeolog (gnaq.S), guanine nucleotide binding protein, alpha q polypeptide (Gnaq), 1110005L02Rik, 6230401I02Rik, AA408290, AW060788, CMC1, Dsk1, Dsk10, G-ALPHA-q, g-alpha-q, Galphaq, GAQ, gaq, Gnaq, gnaqb, Gq, GqI, si:ch73-270f14.2, SWS

Protein level used designations for GNAQ

  • Galpha q
  • gnaqa
  • guanine nucleotide-binding protein G(q) subunit alpha
  • guanine nucleotide-binding protein alpha-q
  • G alpha q
  • guanine nucleotide binding protein alpha q subunit
  • guanine nucleotide binding protein, alpha q polypeptide
  • guanine nucleotide regulatory protein G alpha q
  • heterotrimeric guanine nucleotide-binding protein alpha q subunit
  • guanine nucleotide-binding protein G(q) alpha subunit
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