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GNRHR Produits

(Gonadotropin-Releasing Hormone Receptor (GNRHR))
This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene. [provided by RefSeq, Jul 2008].

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Catégories GNRHR en vedette

GNRHR Anticorps

High quality antibodies with extensive validation data.

GNRHR Kits ELISA

Reliable ELISA kits for a wide range of species.

GNRHR Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

GNRHR recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Rat
Application WB, ELISA, IHC (p), IHC (fro), ICC, IF (cc), IF (p)
Validations
  • (2)
  • (5)
N° du produit ABIN686917
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, ELISA, IHC
Validations
  • (3)
N° du produit ABIN7242191
Quantité 200 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, FACS, IHC (fro)
Validations
  • (4)
N° du produit ABIN966217
Quantité 0.5 mL
Fiche technique Fiche technique

GNRHR recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6967187
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6967186
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6967185
Quantité 96 tests
Fiche technique Fiche technique

GNRHR recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
N° du produit ABIN6964191
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7394573
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
N° du produit ABIN1330111
Quantité 2 μg
Fiche technique Fiche technique

Dernières publications sur nos produits GNRHR

Baek, Park, Park, Kim, Kim, Suh, Kim, Kim, Kim, Nam: "Androgen receptor as a prognostic biomarker and therapeutic target in uterine leiomyosarcoma." dans: Journal of gynecologic oncology, Vol. 29, Issue 3, pp. e30, (2019) (PubMed).

Ciechanowska, Łapot, Paruszewska, Radawiec, Przekop et al.: "The influence of dopaminergic system inhibition on biosynthesis of gonadotrophin-releasing hormone (GnRH) and GnRH receptor in anoestrous sheep; hierarchical role of kisspeptin and RFamide-related ..." dans: Reproduction, fertility, and development, (2018) (PubMed).

Park, Baek, Park, Kim, Nam: "Investigation of hormone receptor expression and its prognostic value in endometrial stromal sarcoma." dans: Virchows Archiv : an international journal of pathology, Vol. 473, Issue 1, pp. 61-69, (2018) (PubMed).

López-Doval, Salgado, Lafuente: "The expression of several reproductive hormone receptors can be modified by perfluorooctane sulfonate (PFOS) in adult male rats." dans: Chemosphere, Vol. 155, pp. 488-97, (2016) (PubMed).

Liu, Li, Zhu, Yu, Guo, Zhou, Zheng, Qu, Huang, Chen, Wang, Ye: "Effects of di-(2-ethylhexyl) phthalate on the hypothalamus-pituitary-ovarian axis in adult female rats." dans: Reproductive toxicology (Elmsford, N.Y.), Vol. 46, pp. 141-7, (2014) (PubMed).

Benz, Le Hir, Norez, Kerbiriou, Calvez, Becq, Trouvé, Férec: "Improvement of chloride transport defect by gonadotropin-releasing hormone (GnRH) in cystic fibrosis epithelial cells." dans: PLoS ONE, Vol. 9, Issue 2, pp. e88964, (2014) (PubMed).

Ko, Guo, Barengo, Naora: "Inhibition of ovarian cancer growth by a tumor-targeting peptide that binds eukaryotic translation initiation factor 4E." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 15, Issue 13, pp. 4336-47, (2009) (PubMed).

Yeung, An, Cheng, Chow, Leung: "Expression and transcriptional regulation of the GnRH receptor gene in human neuronal cells." dans: Molecular human reproduction, Vol. 11, Issue 11, pp. 837-42, (2006) (PubMed).

Cheng, Yeung, Chow, Leung: "Characterization of a new upstream GnRH receptor promoter in human ovarian granulosa-luteal cells." dans: Molecular endocrinology (Baltimore, Md.), Vol. 16, Issue 7, pp. 1552-64, (2002) (PubMed).

Wolfahrt, Kleine, Jarry, Rossmanith: "Endogenous regulation of the GnRH receptor by GnRH in the human placenta." dans: Molecular human reproduction, Vol. 7, Issue 1, pp. 89-95, (2001) (PubMed).

Synonymes et noms alternatifs relatifs à GNRHR

gonadotropin releasing hormone receptor (GNRHR), gonadotropin releasing hormone receptor (Gnrhr), gonadotropin releasing hormone receptor (gnrhr), gonadotropin-releasing hormone receptor (gnrh-r), GH1, gnrh-r, GNRHR, GNRHR1, GNRHR1/III, GNRHR2, gnrhr3/ii, GRHR, HH7, LHRHR, Lhrhr, LRHR, xgnrhr

Protein level used designations for GNRHR

  • gnRH receptor
  • gnRH-R
  • gonadotropin-releasing hormone (type 1) receptor 1
  • leutinizing hormone releasing horomone receptor
  • leutinizing-releasing hormone receptor
  • luliberin receptor
  • type I GnRH receptor
  • GnRH receptor
  • gonadotropin-releasing hormone receptor
  • gonadotropin releasing hormone receptor
  • growth hormone
  • luteinizing-releasing hormone receptor
  • gnoadotropin releasing hormone receptor 2
  • gonadotropin-releasing hormone II receptor
  • type 1/III gonadotropin-releasing hormone receptor hexahelical
  • type 3/II gonadotropin-releasing hormone receptor
  • pituitary GnRH receptor
  • pituitary gonadotropin-releasing hormone receptor
  • LHRH
  • luteinizing hormone-releasing hormone receptor
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